Dermatophyte fungal infections Flashcards

(25 cards)

1
Q

Hair invasion types

A

Endothrix meaning fungal hyphae inside the hair shaft vs. exothrix meaning fungal hyphae inside the hair shaft and on the hair itself

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Classification of dermatophyte infections

A

All ringworm fungi: Microsporum, Trichophyton, and Epidermophyton

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Wet mount prep

A

For skin sample: heat up and then can look at it
For nail: can be left with KOH for 24hrs prior to examining
For hair: no need to prep it, just look under scope

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Mosaic artifact

A

lipid droplets in a line between cells that can look like hyphae, will disappear with more heat and presssure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What type of hyphase in dermatophyte infection

A

branching hyphae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Wood’s light examination

A

On hair:
- microsporum infection and trichophyton floresce blue-green to pale green
On skin:
- tinea versicolor turns white-yello
- Bacterium infection Corneybacterium minuteissiumum causing erythrasma turns bright coral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Two-feet one hand syndrome

A

Usually caused by trichophyton rubrum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Treatment of tinea pedis

A
  • Lamisil (terbinafine) is very effective
  • 2/2 ID reactions may need topical steroids
  • if entire plantar surface affected, more difficult to tx
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Pitted keratolysis

A

Disease mimicking tinea pedis but Bacterial in etiology

on weight bearing part of soles of feet (slimy skin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Pitted keratolysis clinical presentation

A

circular pits &/ furrows

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Pitted keratolysis tx

A

Keep feet dry and antibacterial washing of feet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Tinea cruris vs. candida of the groin

A

Tinea cruris typically presents as unilateral hald moon shaped plaque that does not extend onto scrotum.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

DDx of tinea cruris

A

Candida, intertrigo, erythrasma (scaly throughout not just at advancing border and a more red/brown)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Erythrasma tx

A

Topical azole (but not ketoconazole) or PO erythromycin/clarithromycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Special fungal infections

A
Tinea verrucosum (very red and inflammed, caught from barn animals)
Tinea rubrum (granulomatous rxn)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Is tinea capitis contagious

A

Yes, it can be spread by direct contact/through contaminated clothes unlike other fungal infections

17
Q

Kerion

A

severe inflammatory version of tinea capitis with a boggy, tumor like mass

18
Q

Lab medium for tinea capitis dx

A

Mycosels medium

19
Q

Clinical patterns of tinea capitis

A
Diffuse scale (DDx: seb/atopic derm, psoriasis)
Gray patch (DDx: seb/atopic derm, psoriasis)
Black dot (DDX: alopecia areata, trichotillomania)
Diffuse pustular (bacterial/dissecting folliculitis)
Kerion (DDx: abscess/neoplasia)
20
Q

Tineal capitis tx

A

Need oral antifungals (griseo is drug of choice in kids for 8-10 weeks)

21
Q

MCC of scalp ringworm

A

Trichophyton tonsurans (does not flouresce)

22
Q

Tinea amiantacea

A

Form of seb derm in kids with localized 2-8cm patches of large, brown polygonal shaped scale that adheres to the head and hair as it grows out

23
Q

Tinea barbae tx

A

oral antifungals

24
Q

Tinea barbae differentiation from bacterial folliculitis

A

Tinea usually starts in small area and grows, folliculitis outbreaks widely after shaving. And hair removal is easy and painless in tinea infection but difficult in folliculitis

25
MOA of ntifungals
Azoles: P450 inhibitors Griseo: fungistatic Terbinafine: inhibits squalene epoxidase