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Three underlying mechanisms for ACS
plaque rupture,
plaque erosion, and calcified nodule
Which one is most common and how many %
plaque rupture is
the most common cause (60%) of ACS
plaque erosion is responsible
for how many percent?
22–44% of patients
plaque erosion occurs over lesions
- over lesions rich in smooth muscle cells proteoglycans,
2. with superficial endothelial denudation
The hallmarks
of plaque erosion
- preserved vascular integrity (intact fibrous cap),
- larger residual lumen,
- and platelet-rich thrombus.