Development of Bio;ogy of Sex

Question 1

Genetic Female sex is determined by

Answer 1

Absence of SRY gene

Question 2

Definitive process for Sex Determination and Differentiation

Answer 2

Chromosomal or Genetic Sex

Question 3

Determined at time of fertilization

Answer 3

Chromosomal or Genetic Sex

Question 4

Single most consistent determinant of maleness

Answer 4

Presence of Y chomosomes

Question 5

Does presence of additional X chromosome alter fundamental maleness?

Answer 5

No, as long as you have Y chromosome -> Male

Question 6

Tests for Sex Determination

Answer 6

Sex Chromatin
Hair Root Test
Karyotyping

Question 7

One of the two copies of the X chromosome present in Females is inactivated (Lyon Hypothesis)

Answer 7

Sex Chromatin Test

Question 8

Sex Chromatin Test: 1 Barr body = 1 x chromosome

Answer 8

Normal Female

Question 9

Sex Chromatin Test: 2 Barr bodies = 2 x chromosome

Answer 9

Superfemale

Question 10

Florescent body (Y body) from hair strands
Used in screening large population in Sports

Answer 10

Hair Root Test

Question 11

Most accurate method of sexual determination

Indicated in:
Gender reassignment surgery
Ambiguous genitalia

Answer 11

Karyotyping

Question 12

Development of primary sex organs in response to genetic sex

Answer 12

Gonadal Sex

Question 13

Primitive gonad, outer cortex

Answer 13

Ovary

Question 14

Primitive organ, inner medulla

Answer 14

Testes

Question 15

AOG Formation of Leydig cells

Answer 15

8-9 weeks

Question 16

AOG presence of definitive testes

Answer 16

9 weeks

Question 17

AOG testes descends through inguinal ring

Answer 17

7-9 months

Question 18

AOG maximal development of ovaries

Answer 18

20-25weeks

Question 19

AOG developmental start of ovaries

Answer 19

9 weeks - in the absence of testes formation

Question 20

Regulation of gonadal sex of the differentiation of genital apparatus
Influenced mainly by genetics and hormonal factors

Answer 20

Phenotypic (Genital Sex)

Question 21

Testosterone -> external genitalia

Answer 21

Classic Endocrine Mechanism

Question 22

Testosterone -> Wolffian duct

MIF -> Mullerian duct

Answer 22

Local Paracrine Regulatory Mechanism

Question 23

Responsible for differentiation of Wolffian ducts -> Male internal genitalia

Answer 23

Testosterone - from Leydig Cell

Question 24

Required for conversion of testosterone -> dihydrotestosterone

Answer 24

5-a reductase activity

Question 25

Secretes Mullerian Inhibiting Factor

Answer 25

Sertoli cells

Question 26

Gonadotropic pattern of secretion in males

Answer 26

Tonic (Pulsatile, sustained)

Question 27

Gonadotropic pattern of secretion in Females

Answer 27

Cyclic (Pulsatile but cyclic)

Question 28

Growth and Development of male external genitalia require

Answer 28

Dihydrotestosterone

Question 29

Growth of labia requires

Answer 29

Estrogen

Question 30

Normal female fetus exposure to excess testosterone may cause

Answer 30

Virilization

Question 31

The Wolffian duct is also known as the

Answer 31

Mesonephric duct

Question 32

The Mullerian duct is also known as the

Answer 32

Paramesonephric duct

Question 33

The Wolffian ducts have the potential of differentiating into:

Answer 33

Epididymis Vas Deferens Ejaculatory Duct Seminal Vesicles The wolves Ndidi's Vast Defense Ejected Simon

Question 34

The Mullerian ducts serve as the anlagen of the

Answer 34

Upper Vagina Fallopian Tube Cervix Uterus Mullers upper bag fall from the Service UTE

Question 35

Derivatives of the genital tubercle in males

Answer 35

Glans penis Corpus spongiosum Corpora cavernosa Youtuber Glen's penis went spongy in the cave

Question 36

Derivatives of the genital tubercle in females

Answer 36

Clitoris Vestibular bulb May tubo si Clint sa investment nya sa bulb

Question 37

Derivatives of the urogenital folds in males

Answer 37

Ventral shaft of the penis Males fold their laundry in ventilation shafts

Question 38

Derivatives of the urogenital folds in females

Answer 38

Labia minora Females fold their laundry in Mining Labs

Question 39

Derivatives of the genital swelling or labioscrotal swelling in males

Answer 39

Scrotum and Prepuce

Question 40

Derivatives of the genital swelling or labioscrotal swelling in females

Answer 40

Labia Majora Prepare to be Scrutinized for the swelling in your labi by the Major

Question 41

Derivatives of the urogenital sinus in males

Answer 41

Urethra Cowper glands Prostate gland Sin of Ur Prostitute Cow

Question 42

Derivatives of the urogenital sinus in females

Answer 42

Urethra Lower vagina Bartholin glands Skene glands Sin of Ur Lowering Bag to Bart's Skin

Question 43

Growth of the labia to normal size requires

Answer 43

Estrogen

Question 44

Males or Females: tonic release of gonadotropins

Answer 44

Males

Question 45

Males or Females: cyclic release of gonadotropins

Answer 45

Female

Question 46

Usual distinguishable difference between triple X and normal females

Answer 46

None

Question 47

Disorder of sexual differentiation wherein there is both ovarian and testicular tissues

Answer 47

Hermaphroditism

Question 48

True or Pseudohermaphrodites: functional gonads

Answer 48

True