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Development of the eye Flashcards

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1
Q

The Ectoderm of the eye gives rise to what?

A
  • Lens
  • Part of the Cornea

portion of The eyelids

eyelashes and glands in the eyelids

the lacrimal glands

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2
Q

The neuroectoderm forms the

A
  • Retina
  • Pigmented epithelium of the Irirs
  • Optic Nerve
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3
Q

Mesoderm Forms what in the eye?

A

Cornia Angioblasts of the Chorioid Layer

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4
Q

Neural crest cells migrate into the mesenchyme from the neural crest and differentiate into

A

choroid

and

sclera part of the cornea (corneal endothelium)

The chorid is the innder vascularized layer under the scalera

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5
Q

When does eye development begin?

A

The Start of the 4th week

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6
Q

What is the initial events of formation of the eye

A

Optic Groove

Optic Vesicle

Optic Stalk

GVS

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7
Q

Anophotalmia

A

Optic Vesicle does not form correctly.

Lack of eyes

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8
Q

What is the primordia of the lenses?

A

Lense Placodes Lense Pits Lense Vesicles (PPV)

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9
Q

How are Optic Cups formed

A

The Optic Vesicle invaginates to form a “CUP”

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10
Q

What are “Linear grooves - retinal fissures”

A

Form in the Optic Stalk Future site of the Centeral Artery and Vessel of the retina

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11
Q

When is the Optic Stock Lumen obliterated to become the Optic Nerve?

A

Week 8

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12
Q

What is COLOCBOMA

A

A defect in the eye Caused by incomplete closure of the Retinal Fissures during week 6 Autosomal Dominate

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13
Q

primary vitreous body Where is it found?

A

Between the Optic Cup and the Lens Vesicle.

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14
Q

primary vitreous body What does it do?

A

Lubricates and provides nutrients to the Lens Called Vitreous Humor

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15
Q

What is the pupillary membrane?

A

Branches of the Hyaloid artery called the Tunica Vasculosa Lentis. The Pupillary Membrane is the most anterior portion of this structure.

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16
Q

The pupil forms before/after the degradation of the pupillary membrane?

A

After the degradation of the membrane

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17
Q

What is persistent pupillary membrane?

A

When the pupillary membrane does not completely disintegrate.

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18
Q

What is the cause of congenital cataracts?

A

The most common causes are

  • Trisomy 21
  • Maternal Diabetes
  • Rubella
  • Galactosemia
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19
Q

What are the two layers of the retina?

A

The thick inner layer - holds the nerves for vision The thin outer layer - pigmentation of the retina.

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20
Q

What are the two layers of the retina separated by?

A

Intraretinal Space

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21
Q

When does the intraretinal space disappear?

A

by the 7th week.

(space between the thick and thin membrane)

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22
Q

What is caused by a blow to the eye or head?

A

Retinal detachment.

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23
Q

What is the light sensitive part of the retina?

A

The thick inner layer. - becomes the neural retina

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24
Q

What does the neuro retinal contain?

A

Rods and cones, Cell bodies of neurons

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25
What does the thin-outer wall become?
cuboidal melanin-containing pigmented epithelium.
26
myelination of the eye nerve takes place when?
After 10-12 weeks of light exposure.
27
The mesenchyme (nuero crest orgin) surrounding the optic cup differentiates into what?
inner vascular layer- the choroid outer fibrous layer - the sclera
28
What is the ciliary body?
Wedged shape extention of the Choroid.
29
What function does the ciliary body have?
Ciliary Muscle - focusing the lens Ciliary Process - producing aqueous humor
30
Dranage of the Aqueous Humor is done by the
trabecular Meshwork - Venus drainage and Canal of schlemm-
31
Congenital Glaucoma
Over production of the aqueous Humor ( Ciliary Process) Under drainage problem (Trabecular Meshwork or Canal of Schlemm. Can also be caused by Rubella during pregnancy.
32
The iris is derived from what structure?
The Optic Cup. Both Layers Thick inner and Thin outer
33
Connective tissue of the iris is derived from what/
Neurocrest cells
34
The dilator pupillae is derived from what?
neuroectoderm of the optic cup.
35
What innervates the dilator Pupillae?
Sympathetic nerves from the Superior cervical Ganglion
36
What innervates the sphincter pupillae
Parasympathetic nerves from Edinger Weshphal
37
Eye color is determined by ?
The level of pigment in each layer in the iris Posterior only - blue throughout Iris - brown
38
Cornia formation is induced by what?
The Lens Vesicle.
39
What three sources make up the cornia
* Ecoderm, * Mesoderm * Nurocrest cells
40
When do the eyelids develop?
During the 6th week
41
What makes up the eye lids
* neural crest cell * mesenchyme * Cutanious folds of ectoderm.
42
What is forming during the 26-28 weeks as the eyes are opening?
bulbar conjunctiva and palpebral conjunctiva
43
eyelashes and glands in the eyelids are derived from what?
surface ectoderm.
44
When do the eyes start to open
Week 26-28
45
lacrimal glands develop from
surface ectoderm
46
solid buds from the surface ectoderm canalize to form
nasolacrimal ducts
47
Symptoms of retinal detachment
Phototobia - flashes of light Myopia
48
Lens Part of the Cornea
The Ectoderm of the eye gives rise to what?
49
Retina Pigmented epithelium of the Irirs Optic Nerve
The neuroectoderm forms the
50
Cornia Angioblasts of the Chorioid Layer
Mesoderm Forms what in the eye?
51
choroid sclera part of the cornea (corneal endothelium)
Neural crest cells migrate into the mesenchyme from the neural crest and differentiate into
52
The Start of the 4th week
When does eye development begin?
53
Optic Groove Optic Vesicle Optic Stalk
What is the initial events of formation of the eye
54
Optic Vesicle does not form correctly.
Anophotalmia
55
Lense Placodes Lense Pits Lense Vesicles (PPV)
What is the primordia of the lenses?
56
The Optic Vesicle invaginates to form a "CUP"
How are Optic Cups formed
57
Form in the Optic Stalk Future site of the Centeral Artery and Vessel of the retina
What are "Linear grooves - retinal fissures"
58
Week 8
When is the Optic Stock Lumen obliterated to become the Optic Nerve?
59
A defect in the eye Caused by incomplete closure of the Retinal Fissures during week 6 Autosomal Dominate
What is COLOCBOMA
60
Between the Optic Cup and the Lens Vesicle.
primary vitreous body Where is it found?
61
Lubricates and provides nutrients to the Lens Called Vitreous Humor
primary vitreous body What does it do?
62
Branches of the Hyaloid artery called the Tunica Vasculosa Lentis. The Pupillary Membrane is the most anterior portion of this structure.
What is the pupillary membrane?
63
After the degradation of the membrane
The pupil forms before/after the degradation of the pupillary membrane?
64
When the pupillary membrane does not completely disintegrate.
What is persistent pupillary membrane?
65
The most common causes are Trisomy 21 Maternal Diabetes Rubella Galactosemia
What is the cause of congenital cataracts?
66
The thick inner layer - holds the nerves for vision The thin outer layer - pigmentation of the retina.
What are the two layers of the retina?
67
Intraretinal Space
What are the two layers of the retina separated by?
68
by the 7th week.
When does the intraretinal space disappear?
69
Retinal detachment.
What is caused by a blow to the eye or head?
70
The thick inner layer. - becomes the neural retina
What is the light sensitive part of the retina?
71
Rods and cones, Cell bodies of neurons
What does the neuro retinal contain?
72
cuboidal melanin-containing pigmented epithelium.
What does the thin-outer wall become?
73
After 10-12 weeks of light exposure.
myelination of the eye nerve takes place when
74
inner vascular layer- the choroid outer fibrous layer - the sclera
The mesenchyme surrounding the optic cup differentiates into what?
75
Wedged shape extention of the Choroid.
What is the ciliary body?
76
Ciliary Muscle - focusing the lens Ciliary Process - producing aqueous humor
What function does the ciliary body have?
77
trabecular Meshwork - Venus drainage Canal of schlemm-
Dranage of the Aqueous Humor is done by the
78
Over production of the aqueous Humor ( Ciliary Process) Under drainage problem (Trabecular Meshwork or Canal of Schlemm. Can also be caused by Rubella during pregnancy.
Congenital Glaucoma
79
The Optic Cup. Both Layers Thick inner and Thin outer
The iris is derived from what structure?
80
Neurocrest cells
Connective tissue of the iris is derived from what/
81
neuroectoderm of the optic cup.
The dilator pupillae is derived from what?
82
Sympathetic nerves from the Superior cervical Ganglion
What innervates the dilator Pupillae?
83
Parasympathetic nerves from Edinger Weshphal
What innervates the sphincter pupillae
84
The level of pigment in each layer in the iris Posterior only - blue throughout Iris - brown
Eye color is determined by ?
85
The Lens Vesicle.
Cornia formation is induced by what?
86
Ecoderm, Mesoderm Nurocrest cells
What three sources make up the cornia
87
During the 6th week
When do the eyelids develop?
88
neural crest cell mesenchyme Cutanious folds of ectoderm.
What makes up the eye lids
89
bulbar conjunctiva and palpebral conjunctiva
What is forming during the 26-28 weeks as the eyes are opening?
90
surface ectoderm.
eyelashes and glands in the eyelids are derived from what?
91
Week 26-28
When do the eyes start to open
92
surface ectoderm
lacrimal glands develop from
93
nasolacrimal ducts
solid buds from the surface ectoderm canalize to form
94
Phototobia - flashes of light Myopia
Symptoms of retinal detachment

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