development of the heart Flashcards
1
Q
Mutations in ……….. cause atrial septal defects in humans.
A
NKX2.5
2
Q
The yolk sac is surrounded by
mesoderm populated with blood islands, which contain stem cells that will form the embryonic blood and vasculature. This can be seen in the chick embryo on the left, where these stem cells express a gene called ………….
A
Cpeb4
3
Q
Most common defects include
A
Ventricular septal defects (25% of heart defects, commonest) Atrial septal defects Patent ductus arteriosus Pulmonic stenosis Teratology of Fallot Coarctation of the aorta Aortic stenosis Atrioventricular septal defects
