diabetes Flashcards

(40 cards)

1
Q

what is type I diabetes and what are the risk factors.

A

An autoimmune condition where the body is unable to produce insulin due to the destruction of beta cells in the pancreas.
Risk factors: genetic factors and environmental factors such as early life exposure to viruses

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2
Q

What is type II diabetes and what are the risk factors

A

It is a chronic condition where the pancreas either doesn’t produce enough insulin or the insulin it produces doesn’t work properly
risk factors: obesity, lack of physical activity, family history, ethnicity and diet.

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3
Q

What is gestational diabetes and what are the consequences

A

it is caused by increased insulin demand during pregnancy. It does not usually cause symptoms and mostly discovered when blood sugars are tested.
Consequences include a macrocosmic baby, excess amniotic fluid, pre-eclampsia and premature delivery.

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4
Q

What is MODY (maturity onset diabetes of the young) and what are the 3 main features.

A

It is a hereditary form of diabetes caused by mutation to the genes which effect insulin production.
3 main features include being diagnosed before the age of 25, it runs in families from 1 generation to the next and it can be treated by diet or tablets and doesn’t always need insulin treatment

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5
Q

What is LADA (latent autoimmune diabetes om adults

A

A type of diabetes that straddles type 1 and type 2. It a slow progressing form of autoimmune diabetes - symptoms appear much slower then type I but are more obvious and come on quicker then type 2. It can be managed by diet and exercise and eventually insulin.

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6
Q

What is type 3C

A

Develops because of damage to the pancreas which causes it to stop producing sufficient insulin. It is often linked to other conditions such as pancreatitis, pancreatic cancer and cystic fibrosis.

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7
Q

How is type I and II diabetes diagnosed

A

Random blood glucose of 11.1
Fasting blood glucose of >7
OGT of >11.1 - usually only done in pregnancy
HbA1c - monitors blood glucose control over a 3 month period - 48mmol or 6.5%

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8
Q

How is gestational diabetes diagnosed

A

Fasting blood glucose >5.6mmol
OGTT of >7.8 mmol

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9
Q

What are symptoms of type I

A

polyphagia, polydipsia, polyurea, weight loss, blurred vision, dizziness, fatigue ketoacidosis

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10
Q

What are the symptoms of type II diabetes

A

Polyphagia, polyurea, polydipsia, loss of feeling in the feet or tingling feet, blurred vision, hyperosmolar coma, slow wound healing

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11
Q

What is hypoglycemia and what are the symptoms

A

It occurs when blood glucose levels are <4 mmol/l
Symptoms including sweating, shaking, heart palpitations and feeling tired or confused

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12
Q

What should you do for a hypo

A

It is important to eat something that will raise blood sugar levels quickly such as a small glass of fruit juice, 4 jelly babies, 2 tubes of glucose gel or 5 glucose/dextrose tablets. Check blood sugar levels 10-15 mins later and once above 4mmol, eat something that will keep it up for longer such as biscuits or a sandwich.

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13
Q

What is hyperglycemia and what are the symptoms

A

It is when blood glucose levels are >7mmol before a meal (however target levels are different for everyone).
Symptoms include feeling very thirsty, excessive urination feeling tired tired or weak and weight loss.

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14
Q

What are the consequences of hyperglycemia

A

Retinopathy, neuropathy, nephropathy.

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15
Q

What causes hyperglycemia and how can it be prevented

A

It is caused by missing mediation, having more CHO then your body/medication can cope with, stress, illness/infection
It is prevented by taking medication, avoiding sugary and starchy foods, CHO portions and exercising.

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16
Q

Describe rapid acting insulin.

A

Rapid acting insulin starts to work very quickly and is usually given before a meal to stop blood glucose levels going too high. It starts working withing 10-20 minutes and lasts for up to 5 hours.
It is usually given 15 minutes before a meal but can be taken up 10 minutes after a meal.
It can be combined with intermediate or longer acting insulin for a longer period of blood glucose maintenance.
the 3 types of lisapro, aspart and insulin glulisine.

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17
Q

Give 3 brands of rapid acting insulin

A
  1. Humalog
  2. Lyumjev
  3. novorapid.
18
Q

What is short acting insulin

A

Short acting starts to work after 30-60 minutes and usually lasts for 8 hours. It is usually taken 30 minutes before a meal.

19
Q

Name 2 brands of short acting insulin

A

Humulin S
actrapid

20
Q

What is intermediate acting insulin

A

It had gradual onset and a longer duration of action
It starts to work after 1-2 hours and lasts for 11-24 hours
It is usually taken once or twice a day and works throughout the day and night to give the body low levels of insulin all the time

20
Q

name 2 brands of intermediate acting insulin

A

Humulin I
insulatard

20
Q

What are the brands of long acting insulin

A

levemir
lantus

21
Q

What are diabetes UK guidelines

A

If over weight, lose weight and a low calorie diet of 800-1200 kcals can help achieve weight loss.
Helpful diets include a low CHO diet, Mediterranean diet, intermittent fasting, meal replacement plan.
It also recommends to chose healthier CHO, less salt, eat more fruit and veg, chose healthier fats, cut down on sugar, be smart with snacks, drink alcohol sensibly and avoid diabetic food

21
Q

What is long acting insulin

A

It is us ally injected once or twice a day and works throughout the day and night to give low levels of insulin all the time
It starts working after 30 minutes to 4 hours and usually lasts for 16-24 hours
May need to give short or rapid acting insulin before a meal to stop blood glucose levels going too high after eating CHO.

21
What are the NICE guidelines for type 2 diabetes
- A high fibre, low GI diet - Reduce salt intake - Eat 2 portions of oily fish a week - Choose low fat option - Control intake of sat fat and trans fat - increase physical activity - if overweight, lose 5-10% of body weight.
22
What is GI
GI is a scale ranging from 0-100 and describes how CHO in food effects blood glucose levels. low GI is <55
22
What are the NIH diabetes guidelines
Diabetes ABCs - manage blood sugar levels, manage blood pressure, manage cholesterol. Healthy living can help manage diabetes which involves planning healthy meals by including wholegrain CHO, fruit and veg, protein and dairy. Try to chose foods that include vitamins, Ca, fibre and healthy fat and less sat fat, salt and sugar.
23
what is glycemic load and give examples of low GL foods
GL gives a fuller picture then GI and reflects CHO quantity and quality. It uses GI and the amount of CHO in a serving to estimate how quickly a food causes blood glucose levels to rise and how much blood sugar levels will rise in total after eating. e.g. hummus, lentils, non-fat milk, low fat yoghurt.
24
How does CHO counting differ for patients with type I diabetes and type II diabetes
in type I diabetes, CHO counting helps individuals estimate how much bolus insulin to take with meals. In type 2 diabetes, it can be helpful for those taking insulin, but is less critical for overall diabetes control
25
what are the common complications associated with diabetes
retinopathy neuropathy nephropathy heart attack and stroke hypertension Food problems caused by nerve damage and decrease in circulation to the feet.
26
What methods can dietitians used to monitor and evaluate the effectiveness of dietary interventions in diabetic patients
anthro - BMI, waist circumference, weight - people with type II diabetes are prone to weight gain Biochem - HbA1c, lipids (HDL, LDL, cholesterol, triglycerides), kidneys (prealbumin, eGFR) Clinical - blood pressure, foot exam, eye exam, any symptoms dietary - investigate meal patterns, usual lifestyle, usual food choices and beliefs about food.
27
How can dietitians tailor dietary recommendations to accommodate cultural preferences
Assess individual cultural preferences, beliefs and lifestyles. Have an understanding of traditional foods and recipes and incorporate them in meal plans Help patients find wats to modify traditional recipes to be healthier Have an individual approach rather than applying generic recommendations
28
What dietary adjustments are recommend for patients with CVD
Management of blood pressure and lipids, smoking cessation and a healthy lifestyle are a priority of CVD risk management. This involves reducing trans fat, sat fat and sodium intake
29
What is the mode of action of metformin and what are the side effects
It is the first line therapy and its mode of action is to increase sensitivity to insulin and reduce hepatic gluconeogenesis. It does not usually cause weight gain or hypo's but can cause GI side effects such as nausea, vomiting, diarrhoea and stomach ache.
30
what is the mode of action of alpha-glucosidase inhibitor and what are the side effects
Reduces the rate of CHO digestion in the small intestine, controlling post prandial blood glucose levels Side effects include abdominal pain, bloating, diarrhea and flatulence - it is rarely prescribed in the UK
31
Mode of action of sulfonylureas and side effects
Acts directly on the pancreas to stimulate insulin production. Side effects can include weight gain and hypoglycemia.
32
Mode of action of DPP 4 inhibitors
Prevent the degradation of the enzyme, DPP-4, increasing the concentration incretin hormones which helps the body to produce more insulin. It is weight neutral and side effects include nausea and headaches.
33
mode of action of GLP-1
Increases levels of incretins which helps the body produce more insulin. It can also help with weight loss by reducing appetite and slowing gastric emptying.
34
SLGT2 inhibitor mode of action
prevent reabsorption of 30-50% of glucose in the proximal tubule of the kidney. This promote glucose excretion in urine. It can cause UTIs.
35
Mode of action of thiazolidinediones
Reduces insulin resistance but can cause weight gain and fluid retention