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Diabetes Flashcards

(12 cards)

1
Q

Insulins never to mix

A

Detemir or glargine

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2
Q

Mixing Rule Insulins

A

Clear before Cloudy (NPH = cloudy, regular = clear, fast-acting = clear)

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3
Q

Rapid Acting Insulins

A

Aspart - NovoLog
Lispro - Humalog
Glulisine - Apridra

Give 15 mins before eating

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4
Q

Short Acting Insulins and Intermediate (Basal)

A

Regular - Humulin R (OTC)
Give 30 minutes before eating

NPH - Humulin N (OTC)

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5
Q

Long Acting Insulins

A

Glargine - Lantus

Detemir - Levemir

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6
Q

Sulfonyureas, Meglitinides, Amino acid derivative MOA

A
stimulate release of insulin from pancreatic beta cells
Glyburide - Micronase/DiaBeta
Glipizide - Glucotrol/XL
Glimepiride
Repaglinide - Prandin
Nateglinide - Starlix
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7
Q

Biguanide

A

Metformin - Glucophage
MOA - dec hep glucose prod, dec intest absorp glucose, improves insulin sensitivity
BB - Lactic Acidosis

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8
Q

Alpha-glucosidae inhib

A

Acarbose
Miglitol

MOA - inhib pancreatice alpha-amylase and alpha glucosidaes, block carbs hydrolysis to glucose

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9
Q

THZDs

A

Rosioglitazone - Avandia
Pioglitazone - Actos

MOS - PPAR gamma activator, improve insulin sensitivty

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10
Q

Amylinomimetic

A

Pramlintide - Symlin

MOA - reduce postprand blood sugar, prolong gastric emptying, reduce postprand glucgon secretion, and caloric intake, appetite suppression

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11
Q

GLP-1 Inhib

A

Exenatide - Byetta (BB warn acute pancreatitis and contraind type 1 DM)
Liraglutide - Victoza

MOA - inc insulin secretion, increase B-cell growth/replication, slows gastric emptying, dec food intake

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12
Q

Dipeptidyl-pep 4 inhibitors

A

Sitagliptin - Januvia (Contraind Type 1 DM)
Saxagliptin

MOA - prolong active incretin levels of GLP and GIP

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