Diabetes/Insulin Flashcards

(51 cards)

1
Q

action of amylin

A

works with insulin to lower glucose and delay emptying

increases sensation of satiety (person feels full and stops eating/consuming more carbs)
surpresses glucagon secretion (stops the body from releasing more sugar)
stimulates insulin release (getting rid of the blood glucose thats already there)

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2
Q

glucagon action

A

hormone that causes glycogen to break down energy –> hyperglycemia

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3
Q

glucogen

A

storage form of glucose

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4
Q

long term effects of diabetes

A
angiopathy
PVD peripheral vascular dx
retinopathy
neuropathy
infections
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5
Q

signs and symptoms of diabetes

A
polyphagia
polydipsia    3Ps
polyuria
fatigue 
UTI's
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6
Q

hemoglobin a1c should be at

A

under 6

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7
Q

fasting blood glucose

A

under 100

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8
Q

prediabetes blood glucose

A

100-125

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9
Q

diabetes blood glucose

A

over 125

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10
Q

route insulin therapy is given

A

IV (IV push for severely hyperglycemic)
subQ
inhaled

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11
Q

What type of insulin can we use for needle-phobic people?

A

Insulin Human (afreeza)

insulin pump (is just one needle)

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12
Q

how will type I diabetics use afreeza

A

use with a long-acting insulin

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13
Q

how will type 2 diabetics use afreeza?

A

use in combination with oral anti diabetic therapy

(Notes: Type II receives oral therapy because their hyperglycemia can be caused by other reasons than their beta cells not working)

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14
Q

which is the only insulin i can give VIA IV?

A

Humulin R

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15
Q

Which is the insulin that cannot be mixed with any other insulin?

A

Glargine (Lantus)

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16
Q

dawn phenomenom

A

Early morning spike in blood sugar which can be frustrating to the patient, in spite of them not eating at night

(leaves patient feeling discouraged)

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17
Q

Which two things interfere with early morning spike?

*TEST Q

A

Dawn phenomenom

Somogyi phenomenom

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18
Q

what type of insulin would we use for supplemental insulin coverage?

A

Insulin Regular (novolin R)

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19
Q

what do Sulfonylureas do?

SE?

A

increase secretion of insulin
(can only be effective if theres functioning beta cells)

pt education: monitor for s/s for hypoglycemia

think: since ur increasing insulin production

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20
Q

alpha-glucosidase inhibitor action

A

delay glucose absorption in GI tract causing smaller increase post prandially (

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21
Q

anti-hyperglycemic drug, why?

type?

A

metformin- b/c it increases glucose use by muscle and fat cells

type: biguanide

22
Q

SE of glitzaones (thiazolidinediones)**

A

risk of CHF and edema

23
Q

CI for meglitinides

A

skip dose if u skip meal

24
Q

which drug can i use that causes the growth of beta cells?

type

A

Sitagliptin (Januvia)

dipeptidyl peptidase-4 (DPP-4 Inhibitors)

25
which is the drug that causes you to urinate blood glucose? | type?
Empagliflozin (Jardiance) Canaglifozin (invokana) Dapagliflozin (Farxiga) hint: it will be out in a jiffy, jif sodium glucose transporter 2 inhibitor
26
which drug activates dopamine receptors in the CNS? ******
Bromocriptine (Clycoset) neurotransmitter manipulation- IN BRAIN to control blood glucose
27
How often is eventide (byetta) given
daily
28
How often is Exematide ER (bydureon) given
once a week | subQ
29
amylin drug type SE
Pramlintide (symlin) nausea and *hypoglycemia* Reminder: amylin delays gastric emptying (not going in the SI where glucose is absorbed) creates sensation of fullness
30
route Pramlintide (Symlin) is injected
subcutaneous injection do not mix in the same syringe with insulin
31
What type of medical condition can use an amylin analog?
type II diabetics
32
type II diabetic with needle eversion can use
Pramlintide (symlin)
33
how often is Victoza (liraglutide) taken what type of drug is it
daily VA= daily TTO= weekly GLP
34
how often is Adlyxin (lixisenatide) taken?
daily | VA= daily TTO= weekly
35
Which are the types of GLPs need to be taken weekly
Trulicity (Dulaglutide) Tanzeum (albiglutide) ozempic (semaglutide)
36
SE of GLP's risk of GLP's
hypoglycemia, weight loss Thyroid CA, pancreatitis
37
Xultopgy (IDeglira) is a combination ____(drug type), composed of ___ and ____
GLP Tresiba Victoza (liraglutide)
38
Soliqua (Lixilan) is a combination drug ____ (drug type), composed of ___ and ____
Lantus (insulin glargine) Adlyxin (lixisenatide) (Hint: Lauras initials)
39
Causes hyperglycemia
Bee pollen Gingo biloba glucosamine (impaired beta cell function)
40
How can we treat DKA?
NS for dehydration** | insulin IV drip
41
post up patient meds
insulin with IV dextrose
42
how is glucose gel administered?
buccal
43
pt education for sulfonylureas
pt education: monitor for s/s for hypoglycemia
44
which type of diabetic can use sulfonylureas
type 2- can only work if person has functioning beta cells
45
metformin (type?) | CI?
``` fever sepsis trauma major surgery acidosis hepatic/renal dx CV ot respiratory insufficency hypoxia lactic acidosis ```
46
how often is metformin given
1-2 times a day
47
Januvia type | action
blocks an enzyme that degrades insulin | beta cell neogenesis
48
CI for DD4 drug? | example of drug
Januvia | cannot take with exogenous insulin
49
CI of sodium glucose cotransporter 2 inhibitor
hypoglycemia | DKA- monitor carefully!
50
Dopamine Receptor Agonist- name of drug? CI?
Bromocriptine (Clycoset) taper* *Do not use with ergot drugs
51
Dopamine Receptor Agonist- name of drug? SE?
Bromocriptine (Clycoset) Decreases fatty acids, Decreased bp dec triglycerides dizziness GI symptoms