Diabetes Medication Flashcards

(56 cards)

1
Q

action of secretagogues

A

increases insulin secretion from pancreas

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2
Q

2 types of secretagogues

A

sulfonylureas

meglitinidine analogues

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3
Q

3 actions of sulfonylureas

A

stimulates insulin secretion

prevents glycogenolysis

improves insulin sensitivity

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4
Q

action of meglitinide analogues

A

stimulates insulin secretion

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5
Q

type of starch blocker

A

alpha glucosidase inhibitor

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6
Q

2 actions of alpha glucosidase inhibitors

A

slows carbohydrate absorption

slows digestion of starch

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7
Q

2 types of meds that improve insulins effect

A

biguanides

thiazolidinediones

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8
Q

3 actions of biguanides

A

reduces glycogenolysis in the liver

reduces GI glucose absorption

improves insulin sensitivity

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9
Q

3 actions of thiazolidinediones

A

improves insulin sensitivity

reduces hepatic glycogenolysis

decreases appetite

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10
Q

type of incretin mimetic

A

GLP-1 agonist

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11
Q

3 actions of GLP-1 agonists

A

promotes insulin secretion

decreases glucagon

decreases gastric emptying

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12
Q

type of insulin support medication

A

amylin analogues

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13
Q

3 actions of amylin analogues

A

inhibit glucagon release

decrease gastric emptying

decrease hunger and food intake

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14
Q

type of medication that improves the action of incretins

A

DPP-4 Inhibitors

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15
Q

3 actions of DPP4 inhibitors

A

promote insulin secretion

promote glucagon suppression

prolongs incretin actions

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16
Q

type of renal glucose resorption blockers

A

SGLT2 inhibitors

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17
Q

2 actions of SGLT2 inhibitors

A

block resorption of glucose in the kidneys

increases renal excretion of glucose

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18
Q

3 types of rapid acting insulin

A

Humalog

Novalog

Apidra

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19
Q

Rapid acting insulin

onset, peak, duration

A

5-15 minutes

1-1.5 hours

3-5 hours

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20
Q

type of short acting insulin

A

regular

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21
Q

short acting insulin (regular)

onset, peak, duration

A

0.5-1 hour

2-4 hour

5-8 hour

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22
Q

type of intermediate acting insulin

A

NPH

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23
Q

intermediate acting insulin (NPH)

onset, peak, duration

A

2-4 hours

4-10 hours

10-16 hours

24
Q

3 types of long acting insulin

A

Lantus

Levemir

Toujeo

25
onset and duration of Lantus
2-4 hours 20-24 hours
26
onset and duration of Toujeo
6 hours 24-36 hours
27
onset and duration of Levemir
2-4 hours 6-23 hours
28
can reduce A1C by 1-2% can become less effective as beta cell destruction progresses
sulfonylureas
29
must be given before meals prescribed when sulfonylureas are not effective or when hypoglycemia occurs with them
meglitinidine analogues
30
do not have a potent glucose effect lower post-prandial sugar levels (affect absorption)
alpha glucosidase inhibitors
31
first line of treatment for type 2 diabetes and prediabetes
biguanides | (ex: metformin)
32
medication type that causes less of a chance of hypoglycemia used more in geriatric populations
DPP4 inhibitors
33
long acting insulin meets body's metabolic needs
basal insulin
34
prevents post prandial hyperglycemia
pre-prandial insulin
35
2 types of pre-prandial insulin
regular (short) NPH (intermediate)
36
prevents post-prandial hyperglycemia shoot and eat
prandial
37
3 types of prandial insulin
humalog novalog apidra
38
order of absorption speeds for injections
abdomen arm thigh buttocks
39
order of mixing insulins
shorter acting first, then longer | (first clear, then cloudy)
40
lipodystrophy
degenerative changes to adipose tissue
41
lipoatrophy
small depression develops under skin
42
lipohypertrophy
raised area in skin seen when injection is given in the same site over a long period of time
43
somogyi effect
low blood glucose in the evening causes a rebound effect in the body causes hyperglycemia in the early morning seen with long acting insulin
44
dawn phenomenon
normal nighttime BGL hyperglycemia in the AM
45
how to prevent dawn phenomenon
excercise later in the day limit carbs before bed adjust insulin
46
how to prevent somogyi effect
high carb snack before bed check BGL in middle of night adjust insulin dose
47
amount of insulin needed for 24 hour period
0.5-0.7 units per kg
48
amount of insulin needed in 24 hour period if patient is 150% of normal body weight
1.5-2 units/kg
49
5 goals of nutrition therapy
portion sizes nutrient dense foods low glycemic index reduce calories, sodium, fatty red meats limit alcohol
50
recommendation of protein per day
15-20% of calories
51
how much protein per day should someone with nephropathy eat
0.8mg/kg
52
recommendation of fats per day
20-30% type is more important than the amount (Omega 3)
53
recommendation of sodium per day
2,300mg (salt substitute not recommended)
54
recommendation of fiber per day
20-35g
55
Can help rapid alleviate the increase of post-prandial BGL
fiber
56
\_\_\_\_\_ can occur after exercise
hypoglycemia