Diabetes Mellitus

Question 1

Lispro

Answer 1

rapid-acting insulin, meal time insulin

Question 2

Regular insulin

Answer 2

short acting, meal time

Question 3

Neutral protamien hagedorn

Answer 3

intermediate acting, controls glucose levels between meals

Question 4

secretagogues: sulphonylureas (Glyburide)

Answer 4

stimulate beta cells in pancreas to increase insulin production, with breakfast

Question 5

Secretagogues: Non-sulphonylureas

Answer 5

stimulate beta cells in pancreas to increase insulin production, meal time drugs

Question 6

Metformin

Answer 6

decreases hepatic production of glucose and increase tissue sensitivity to insulin, 1st line treatment for type 2

Question 7

rosiglitazone

Answer 7

decrease insulin resistances

Question 8

DPP-4 inhibitors

Answer 8

blocks DPP-4, reducing incretin metabolism and longer breakdown, increases plasma incretin level and decrease glucose

Question 9

exenatide

Answer 9

mimics GLP-1 incretin which stimulates insulin and inhibits glucagon to lower blood glucose

Question 10

canagliflozin

Answer 10

inhibit SGLT2 in proximal tubule and causes glucose to no be reabsorbed in and glucose is lost in the urine