Diabetes pharm Flashcards

(59 cards)

1
Q

oral incretin mimetic

A

semaglutide

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2
Q

twice daily mimetics

A

exenatide

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3
Q

one daily mimetics

A

liraglutide, lixizenatide

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4
Q

once weekly mimetic

A

exenatide ER, Trulicity, ozempic

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5
Q

GLP-1 agonist MOA

A

enhances glucose dependent insulin secretion by the beta cells, suppresses glucagon secretion, slows gastric emptying, increases satiety

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6
Q

indication for incretin mimetics

A

monotherapy or adjunct therapy in patients taking metformin, SU, or TZD

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7
Q

3 day window for missed dose – glp agonist

A

exenatide ER, albigulutide, dulaglutide

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8
Q

5 day window for missed dose – glp agonist

A

5 day window for missed dose

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9
Q

rapid acting insulin types

A

insulin lispro, insulin aspart, insulin gluisine, inhaled human insulin

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10
Q

insulin lispro brand name

A

humalog

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11
Q

insulin lispro onset

A

15-30 minutes

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12
Q

insulin aspart brand name

A

novolog and fiasp

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13
Q

novolog onset

A

15-30 minutes

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14
Q

fiasp onset

A

5-20 minutes

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15
Q

insulin glulisine brand name

A

apidra

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16
Q

apidra onset

A

15-30 minutes

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17
Q

inhaled human insulin brand name

A

afrezza

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18
Q

afrezza onset

A

12-15 minutes

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19
Q

peak time for rapid-acting insulin

A

1-2 hours

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20
Q

duration for rapid acting insulin

A

3-5 hours

2.5-3 for afrezza

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21
Q

short acting insulin

A

regular insulin (U-100)

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22
Q

regular insulin brand name

A

Humulin R, Novolin R

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23
Q

onset for short acting

A

30-60 minutes

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24
Q

peak for short acting

25
duration for regular insulin
6-8 hours
26
intermediate-acting insulin
NPH insulin, regular insulin (U-500)
27
NPH insulin brand name
Humulin N, Novolin N
28
NPH onset
2-4 hours
29
NPH peak
4-6 hours
30
NPH duration
8-12 hours
31
regular insulin U-500 brand
Humulin R
32
Humulin R onset
30-60 minutes
33
Humulin R peak
2-3 hours
34
Humulin R duration
15-24 hours
35
long-acting insulin
insulin detemir, insulin glargine 100 and 300, insulin degludec
36
long acting insulin peaks
relative flat peak
37
insulin detemir brand
Levemir
38
insulin detemir onset
2-4 hours
39
insulin detemir duration
14-24 hours
40
insulin glargine 100 brand
lantus
41
lantus onset
2-4 hours
42
lantus duration
22-24 hours
43
insulin glargine 300 brand name
toujeo
44
toujeo onset
6 hours
45
toujeo duration
24-30
46
insulin degludec brand
tresiba
47
Tresiba onset
30-90 minutes
48
Tresiba duration
42 hours
49
Humulin 70/30
70% NPH and 30% regular insulin
50
Novolin 70/30
70% NPH and 30% regular insulin
51
Humalog 75/25
75% insulin lispro protamine suspension with 25% insulin lispro
52
Humalog 50/50
50% insulin lispro protamine suspension with 50% insulin lispro
53
NovoLog 70/30
70% insulin aspart protamine suspension with 30% insulin aspart
54
lispro timing before food
0-15 minutes
55
aspart timing before food
0-15 minutes | 5 ac; 20 pc
56
glulisine timing before food
0-15 min
57
afrezza timing before food
0 min
58
regular insulin 100 timing before food
30 min
59
NPH mix
lispro, aspart, regular