DIABETES TECHNOLOGY: PUMPS, SENSORS, AND BEYOND Flashcards

(60 cards)

1
Q

What is a continuous subcutaneous insulin infusion (CSII) device?

A

A small, wearable, portable device that delivers preprogrammed and user-adjusted doses of insulin both continuously and in boluses.

More commonly known as an ‘insulin pump’, this device is used in lieu of multiple daily injections (MDIs).

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2
Q

What are the components of a CSII device?

A

The main components include:
* Insulin pump
* Reservoir
* Infusion sets

Each component plays a crucial role in the delivery of insulin.

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3
Q

How does the insulin pump work?

A

It delivers basal insulin continuously and boluses based on user input for food intake and corrections.

Basal infusion rates and bolus settings are tailored to each patient’s needs.

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4
Q

What settings are programmed into the insulin pump?

A

The settings include:
* Carbohydrate-to-insulin (CI) ratio
* Correction factor (CF)
* Blood glucose targets

These settings help the pump calculate the necessary insulin for meals and corrections.

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5
Q

What type of insulin is used in a CSII device?

A

Rapid-acting insulin, such as:
* Lispro (Humalog)
* Aspart (Novolog)
* Glulisine (Apidra)

Rarely, concentrated insulin (U-500 regular insulin) is used for those with significant insulin resistance.

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6
Q

How does CSII improve glycemic control?

A

It improves glycemic control by:
* Better matching of basal insulin delivery
* More consistent and accurate bolus dosing

Preprogrammed CI ratios and CFs reduce the risk of calculation errors.

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7
Q

True or False: Long-acting insulins are used in insulin pumps.

A

False

Intermediate or long-acting insulins are not used in insulin pumps.

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8
Q

Fill in the blank: The _______ is a cartridge that holds a three-day supply of rapid-acting insulin.

A

reservoir

The reservoir is changed every three days when the insulin infusion site is changed.

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9
Q

What is the function of the infusion set in a CSII device?

A

It is inserted subcutaneously to deliver both basal and bolus insulin.

The infusion set includes a fine needle that is removed after insertion, leaving the cannula under the skin.

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10
Q

What is a carbohydrate-to-insulin (CI) ratio?

A

It is the grams of carbohydrates that will be covered by one unit of bolus insulin.

This ratio helps determine the amount of insulin needed for meals.

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11
Q

What is a correction factor (CF)?

A

An estimate of how much each additional unit of bolus insulin is expected to lower an elevated premeal blood glucose.

It is also known as the insulin sensitivity factor.

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12
Q

How does the insulin pump calculate bolus doses?

A

It uses preprogrammed settings for carbohydrate intake and blood glucose levels to determine the necessary bolus.

This automated calculation helps reduce manual errors.

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13
Q

Fill in the blank: Insulin pumps allow for bolus delivery in increments smaller than _______.

A

a half unit

This feature allows for more accurate dosing, particularly for insulin-sensitive patients.

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14
Q

What is the significance of varying basal insulin rates in insulin pumps?

A

They closely mimic true physiology by adjusting insulin delivery according to the body’s needs throughout the day.

This flexibility can enhance glycemic control.

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15
Q

What kind of insulin is used in a CSII device?

A

Rapid-acting insulin such as lispro (Humalog), aspart (Novolog), and glulisine (Apidra)

Rarely, concentrated insulin (U-500 regular insulin) is used for individuals with significant insulin resistance.

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16
Q

How does CSII improve glycemic control?

A

Through better matching of basal insulin delivery and more consistent bolus dosing

Reduces risk of math errors and allows for easier administration of insulin boluses.

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17
Q

Who is a good candidate for an insulin pump?

A

Patients with inadequate glycemic control despite intensive therapy with MDIs, high glucose variability, or those desiring more flexibility

Candidates must be motivated and knowledgeable about diabetes self-management.

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18
Q

Are insulin delivery settings on a CSII device universal?

A

No, they must be titrated to each patient’s individual needs

Frequent monitoring and consistent follow-up with healthcare professionals are essential.

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19
Q

What basic knowledge does a patient need to be started on an insulin pump?

A

Carbohydrate counting, understanding insulin pump functions, and responding to real-life scenarios

Awareness of how to avoid and respond to hypoglycemia is also important.

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20
Q

How much patient input is required to safely and effectively operate an insulin pump?

A

Considerable input is required, including frequent blood glucose testing and estimating carbohydrate contents

Patients must also change infusion sites every 3 days.

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21
Q

What are the major challenges for patients who use insulin pumps?

A

Accurately counting carbohydrates and frequently checking blood glucose levels

Challenges also include device-related issues like leaking insulin or kinking of the cannula.

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22
Q

What are the major complications that patients face while using a CSII device?

A

Inadequate glycemic control, hyperglycemia, and hypoglycemia

Correcting settings to eliminate hypoglycemia takes priority.

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23
Q

What are the major differences between the insulin pumps currently available on the market?

A

Major brands include Medtronic, T-Slim, and Omnipod

Omnipod pumps do not require tubing and can communicate with CGMs for continuous glucose monitoring.

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24
Q

Fill in the blank: The type of insulin that is NOT used in insulin pumps is _______.

A

Intermediate or long-acting insulins

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25
True or False: Insulin pumps can independently control blood glucose levels.
False
26
What is a CGM?
A CGM is a device that allows for real-time monitoring of glucose levels every 5 minutes or more, using a subcutaneous catheter to sample extracellular fluid.
27
What are the three major CGM brands available in the United States?
* Dexcom * Libre * Guardian
28
How does a CGM work?
A glucose sensor inserted under the skin measures glucose levels in interstitial fluid and transmits the data via wireless radiofrequency to a display device.
29
What information do CGM systems provide apart from blood glucose levels?
They provide information on the rate of blood glucose change, indicated by arrows showing direction and rate of change.
30
What do one arrow up or down indicate in CGM readings?
One arrow indicates a change of approximately 1 mg/dL/min (60 mg/dL/hr).
31
What do two arrows up or down indicate in CGM readings?
Two arrows indicate a change of about 2 mg/dL/min (120 mg/dL/hr).
32
What is a benefit of CGM devices providing audible alarms?
They warn patients before hyperglycemic or hypoglycemic values occur, allowing for preemptive actions.
33
How can CGM data be used in patient care?
Data can be downloaded and reviewed during visits, leading to informed changes in insulin regimens and improved HbA1c values.
34
What are two major problems with CGM systems?
* Glucose in extracellular fluid lags behind capillary blood glucose by approximately 15 minutes * Certain medications can interfere with accurate readings.
35
What is a hybrid closed-loop insulin delivery system?
It consists of an insulin pump and a CGM that communicate to automate basal insulin delivery adjustments.
36
What is an example of a hybrid closed-loop insulin delivery system available in the U.S.?
Medtronic 670G.
37
How does a hybrid closed-loop insulin delivery system work?
The CGM senses real-time glucose values and transmits them to the insulin pump, which adjusts basal insulin delivery accordingly.
38
What must patients estimate when using a hybrid closed-loop system?
The carbohydrate content of food to be consumed for accurate mealtime insulin boluses.
39
What happens if a patient does not enter carbohydrate intake for a mealtime bolus?
The system will detect increasing blood glucose levels and temporarily increase the basal insulin delivery rate.
40
Is titration of insulin required in a hybrid closed-loop system?
Yes, titration is required but is less intensive compared to traditional insulin delivery methods.
41
What must be preprogrammed for traditional pump settings in manual mode?
Traditional pump settings must be preprogrammed for periods when the system exits automatic mode.
42
What needs to be assessed and adjusted due to patient input requirements in a hybrid closed-loop system?
The carbohydrate-to-insulin (CI) ratio needs to be assessed and adjusted as needed.
43
What is a disadvantage of the hybrid closed-loop insulin delivery system?
It may not be ideal for more intensive glycemic targets such as pregnancy or patient preference. ## Footnote Currently, the only hybrid closed-loop system approved by the FDA is the Medtronic 670G, designed to maintain a stable blood glucose level of 120 mg/dL.
44
What is a smart insulin pen?
A device that records the date, time, and amount of insulin taken and can communicate via Bluetooth with a smartphone app. ## Footnote Smart insulin pens may also allow for half-unit insulin dosing.
45
How do smart insulin pens assist patients?
They provide a record of insulin administration and can give reminders or recommendations on dosing through a smartphone app. ## Footnote Smart pens do not directly attach to the body and offer portability without the disadvantages of a vial and syringe.
46
Who is a good candidate for a smart insulin pen?
Patients not candidates for insulin pumps or those who decline pump therapy but need more intensive insulin administration. ## Footnote Smart pens are not often used due to the availability of insulin pumps.
47
What types of apps are available for people with diabetes?
Apps for carb counting and tracking blood glucose, activity levels, meals, and insulin doses. ## Footnote Common free apps include MyFitnessPal, Calorie King, and SparkPeople. Paid apps include Dario and Diabetes:M.
48
Fill in the blank: Smart insulin pens can communicate via _______ with a smartphone.
Bluetooth
49
True or False: Smart insulin pens directly attach to the body.
False
50
List three common free apps for helping with carb counting.
* MyFitnessPal * Calorie King * SparkPeople
51
What is the primary purpose of a smart insulin pen?
To record insulin administration and improve dosing management.
52
What is a continuous subcutaneous insulin infusion device commonly known as?
Insulin pump ## Footnote A wearable, portable device that delivers preprogrammed and user-adjusted doses of rapid-acting insulin.
53
How can an insulin pump benefit diabetes management?
It may improve hemoglobin A1c and glucose variability ## Footnote Through optimized matching of basal insulin delivery to basal insulin requirements and improved meal-time insulin management.
54
What factors require adjustments to insulin pump settings over time?
Glucose patterns from daily fingersticks or CGM data ## Footnote Patients should have close follow-up with a diabetes care provider to review glucose data.
55
What does CGM stand for?
Continuous Glucose Monitor ## Footnote A device that allows for real-time monitoring of glucose levels throughout the day and night.
56
How frequently can a CGM take glucose readings?
As often as every 5 minutes ## Footnote This allows patients to make changes to prevent episodes of hyper- or hypoglycemia.
57
What is a key limitation of CGM readings?
There is a 15-minute lag behind blood glucose values ## Footnote Because the CGM measures glucose in the interstitial fluid.
58
What is a hybrid closed-loop system?
An insulin pump and CGM that communicate to maintain glucose within a target range ## Footnote The user must input carbohydrate content of food for mealtime insulin delivery.
59
True or False: A CGM provides immediate blood glucose readings.
False ## Footnote There is a 15-minute lag in readings.
60
Fill in the blank: The user of a hybrid closed-loop system is required to input _______ content of food.
carbohydrate ## Footnote This is necessary for the pump to deliver mealtime insulin boluses.