diabetic drugs

Question 1

what type of drug is metformin?

Answer 1

biguinive

Question 2

what are the side effects of metformin?

Answer 2

Nausea and vomiting
GI discomfort
Acute kidney injury
Lactic acidosis

Question 3

what are examples of sulphonyureas?

Answer 3

(gliclazide, glibenclamide)

Question 4

how does metformin work?

Answer 4

Reduces hepatic gluconeogenesis

increases insulin sensitivity

Question 5

how do sulphonylureas work?

Answer 5

Bind to and close ATP-K+ channel on Beta cells causing depolarisation and insulin release

Question 6

what are the side effects of sulphonyureas?

Answer 6

Weight gain

Hypoglycaemia

Question 7

what type of drug is pioglitazone?

Answer 7

thiazolidinedione

Question 8

how do thiazoladinediones work?

Answer 8

reduce peripheral insulin resistance

Question 9

what are the main side effects of thiazolidinediaones?

Answer 9

Weight gain
Fluid retention
Hepatotoxicity
Bladder cancer

Question 10

what are examples of DPP4 inhibitors?

Answer 10

sitagliptin

Question 11

how to DPP4 inhibitors work?

Answer 11

prevent degredation of incretins, thus promoting insulin secretion

Question 12

what is the main side effect of sitagliptin?

Answer 12

DPP4 inhibitors like sitagliptin can cause pancreatitis

Question 13

what are examples of SGLT-2 inhibitors?

Answer 13

dapagliflozin

empagliflozin

Question 14

what is the mechanism of action of SGLT2 inhibitors?

Answer 14

urinary exertion of glucose

Question 15

what is the main side effect of SGLT2 inhibitors?

Answer 15

UTIs sue to glucosuria increasing the risk of infection

Question 16

which type of antidiabetic causes weight loss?

Answer 16

GLP1 mimetic like liragutide

Question 17

wha type of anti diabetic is liragutide?

Answer 17

GLP1 mimetic

Question 18

wha are the main side effects of GLP-1 mimetics?

Answer 18

Reduced appetite
Nausea and vomiting
Pancreatitis