Diabetic Medications Flashcards
(26 cards)
Actions of Metformin
Actually decreases insulin resistance.
Reduces hepatic glucose production.
Improves insulin sensitivity.
Reduces intestinal absorption of glucose.
Metformin has a low risk of
hypoglycemia
Metformin has a high risk of
lactic acidosis
Metformin can cause:
Weight Loss
GI Side Effects
Dose dependent diarrhea
Metformin requires a safe level of
kidney function
Suflonylurea has a high risk of
hypoglycemia - specifically the long acting forms.
Mechanism of Sulfonylurea
stimulates insulin release of pancreatic beta cells and reduces glucose output from the liver.
Thiazolidones improves
insulin resistance.
Thiazolidones are contraindicated for
Class III and IV heart failure.
Thiazolidones can cause
weight gain.
Best time to give Maglitinides
before meals.
Action length of Maglitinidines
SHORT!
Maglitinides are given with
meals.
What insulin is preferred in renal failure?
Maglitinides.
Maglitinides have a low risk of
hypoglycemia.
Maglitinides are metabolized by…
the liver.
Side effects of Alpha-glucosidase inhibitors
Bloating and Diarrhea
Mechanism of Action for Alpha-glucosidase inhibitors
Reduces absorption of glucose.
Facts about DPP-IV Inhibitors
Weak in general
Weight neutral
No risk of hypoglycemia
GLP-1 Agonist can cause
weight loss.
GLP-1 Agonist have no risk of
hypoglycemia.
Most common side effects of GLP-1 Agonists
Nausea and Vomiting
Few reports of pancreatitis cases.
What drug helps reduce postprandial hyperglycemia?
Bramlintiede.
Bramlintiede helps prolong…
gastric emptying time.
