Diarrhea Flashcards

(55 cards)

1
Q

What is Increased stool frequency

a) (more than 3 BM’s QD
(b) Liquidity of feces

A

Diarrhea

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2
Q

Diarrhea acute in onset and persisting for less than 2 weeks is most commonly caused by ___________, ___________
(either preformed or produced in the gut).

A

infectious agents, bacterial toxins

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3
Q

Infectious sources can be transmitted by __________, _______ and __________. Also usually has incubation periods between ________ hours.

A

fecal- oral contact, food and water

12 and 72 Hours

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4
Q

Pertinent Anatomy for diarrhea

A

(1) Small intestine
(2) Large intestine (colon)
(a) Cecum
(b) Rectosigmoid Colon

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5
Q

Pertinent Physiology

the ______ is the prime absorptive surface of the gastrointestinal tract.

A

Small intestine

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6
Q

Pertinent Physiology

>90% of all water absorbed in the GI tract takes place where

A

Small intestine

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7
Q

What part of the small intestine is the major site of water resorption

A

Jejunum

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8
Q

Disorders of the small intestine result in increased amounts of diarrheal fluid with a concomitantly greater loss of ______, ________ and ____

A

water, electrolytes, and nutrients

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9
Q

_______ are the most common causes of acute gastroenteritis

A

Infectious agents

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10
Q

Acute Infectious gastroenteritis is a common diarrheal illness seen in the _____ setting

A

Operational

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11
Q

What is the definition of diarrheal disease

A

three or more times per day or at least 200 g of stool per day

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12
Q

______ is defined as diarrheal disease of rapid onset that lasts less than two weeks and may be accompanied by nausea, vomiting, fever, or abdominal pain.

A

Acute gastroenteritis

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13
Q

Acute gastroenteritis involves the inflammation of the ____ and _____

A

stomach and portions of the small intestine

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14
Q

True/False

in acute Gastroenteritis both vomiting and diarrhea are usually present; however, either can occur alone.

A

True

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15
Q

Gastritis vs gastroenteritis

A

Gastritis involves ONLY the stomach

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16
Q

The two most common causes of gastritis are

A
  • Chronic NSAID use
  • Chronic alcohol use and/or large amounts of alcohol consumption
  • Other etiologies for gastritis include trauma and critically ill patients that are admitted to the ICU.
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17
Q

Gastritis is typically self limited but patients may benefit from what treatment?

A

PPI and removal of the offending agent

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18
Q

If gastritis does not resolve with conservative management, consider referral for what testing?

A

endoscopy and H. Pylori testing

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19
Q

Chronic Diarrheal illnesses may be classified as

A
Secretory
Inflammatory
Chronic Infections
Malabsorption syndromes
Osmotic
Motility disorders
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20
Q
What chronic diarrheal illness?
due to an increase in the osmotic load presented to the intestinal lumen, either through excessive intake or diminished absorption
Such as:
1) Medications
2) Zollinger- Ellison Syndrome
A

Osmotic

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21
Q

What chronic diarrheal illness?

when the mucosal lining of the intestine is inflamed

A

Inflammatory (or mucosal),

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22
Q

What chronic diarrheal illness?

when increased secretory activity occurs

A

Secretory

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23
Q

What is a parasite that can cause a chronic diarrheal illness

A

Giardia Lamblia

24
Q

Chronic Diarrheal illnesses
These are examples of what?
Celiac disease, Whipple, Crohn disease, Lactose
Intolerance

A

Malabsorption syndromes

25
Irritable bowel syndrome is what type of disorder?
Motility disorder
26
From a diagnostic and therapeutic standpoint, it is helpful to classify infectious diarrhea into syndromes that
1) produce inflammatory or bloody diarrhea | 2) non- inflammatory, non-bloody, or watery
27
The term _________ suggests colonic involvement by invasive bacteria or parasites or by toxin production
"inflammatory diarrhea"
28
What classification of Acute Infectious Diarrhea Patients complain of frequent bloody, small-volume stools, often associated with fever, abdominal cramps, tenesmus, and fecal urgency.
"inflammatory diarrhea"
29
Common organisms that cause "inflammatory diarrhea" are
Shigella, Salmonella, Escherichia coli, E coli O157:H7
30
What is a common protozoal cause of Inflammatory diarrhea?
Entamoeba histolytica
31
Community outbreaks (including nursing homes, schools, cruise ships) suggest a .........
viral etiology or a common food source
32
Similar recent illnesses in family members suggest
an infectious origin
33
Ingestion of improperly stored or prepared food implicates
food poisoning
34
What type of diarrhea is generally milder and is caused by viruses or toxins that affect the small intestine.
Acute Non-inflammatory diarrhea
35
What type of diarrhea interferes with salt and water balance, resulting in large-volume watery diarrhea, often with nausea, vomiting, and cramps
Acute Non-inflammatory diarrhea
36
Acute Non-inflammatory diarrhea | Common causes
-rotavirus -Norwalk virus Vibrio cholerae virus Vibrio parahaemolyticus -enterotoxin- producing E coli -other agents that can cause food-borne gastroenteritis
37
Common Protozoal causes of acute Non- inflammatory diarrhea
Giardia Lamblia, cryptosporidium cyclospora
38
What term denotes diseases caused by toxins present in consumed foods
"food poisoning"
39
When should a stool sample should be sent for fecal leukocyte, ovum and parasite evaluation, and bacterial culture
If diarrhea worsens or persists for more than 7 days
40
What is indicated for these (a) Signs of inflammatory diarrhea manifested by any of the following: fever (> 38.5 degree Celcius), bloody diarrhea, or abdominal pain. (b) The passage of six or more unformed stools in 24 hours. (c) Profuse watery diarrhea and signs or symptoms of dehydration.
Prompt medical evaluation
41
What labs would you get for Diarrhea
(1) CBC/DIFF (2) Fecal leukocyte (3) Fecal O/P (4) Stool culture (5) C difficile assay, if recent hospitalization or antibiotics (6) Stool examination for Giardia Lamblia if Giardias is suspected
42
What is an important cause of waterborne and foodborne disease, daycare center outbreaks, and illness in international travelers?
Giardia Lamblia (Giardiasis)
43
The goal of treatment for diarrhea is what
to allow for symptoms to subside
44
Stopping the diarrhea abruptly with antidiarrheal could do what?
prolong symptom relief if causes are ingested bacteria, parasites, etc.
45
True/ False Most mild diarrhea will not lead to dehydration provided the patient takes adequate oral fluids containing carbohydrates and electrolytes.
True
46
_______may be used safely in patients with mild to moderate diarrheal illnesses to improve patient comfort.
Antidiarrheal agents
47
True/False | Empiric Antibiotic therapy is normally indicated in patients with acute, community-acquired diarrhea
False | normally not indicated
48
The infectious bacterial diarrheas for which for which antibiotic treatment is recommended are:
``` shigellosis cholera salmonellosis listeriosis C. difficile ```
49
The parasitic infection treatment is required for......
amebiasis giardiasis cryptosporidiosis
50
how do you treat Chronic Non-Infectious Diarrheal illnesses
Treat the underlying causes.....
51
What is preferred in patients with severe dehydration or those that cannot drink enough orally?
Intravenous fluids (lactated Ringer injection)
52
What diet would you recommend to your patient?
BRAT diet; avoid irritating foods
53
Antidiarrheal Agents used
- Loperamide (Imodium) | - Bismuth subsalicylate (Pepto- Bismol) - anti-diarrhea
54
Bismuth subsalicylate (Pepto- Bismol) - anti-diarrheal dose
Dose: 2 tablets or 30 mL PO q 30-60 min as needed, | Max 16 tablets or 240 mL/24 hours
55
Loperamide (Imodium) - anti- diarrheal, Dose
4mg initially, then followed by 2mg after each loose stool | maximum dose of 16mg/day