Diazepam (Valium)

Question 0

Actions

Answer 0

1. Anticonvulsants
2. Depresses CNS, PNS & ANS
3. Decreases recall (cardioversion)

Question 1

Classification

Answer 1

Anticonvulsant
Sedative
Muscle relaxant
(Benzodiazepine)

Question 2

Indications

Answer 2

1. Active seizure activity

2. Sedation prior to cardioversion

Question 3

Contraindications

Answer 3

1. Shock/hypotension
2. ETOH
3. Acute narrow-angle glaucoma

Question 4

Relative Contraindications

Answer 4

Head injury (w/ ⬇️ CNS function)

Question 5

Adverse effects

Answer 5

CARDIO- bradycardia, tachycardia, hypotension
RESP- depression/hypoventilation, apnea
NEURO- dizziness, confusion, blurred vision, restlessness, slurred speech
OTHER- worsens glaucoma, phlebitis

Question 6

Administration

Answer 6

5-10mg slow (5mg/min) IVP
Titrate to stop seizure activity or until sedation occurs for cardioversion.
May repeat 5mg/min to max 20mg

Question 7

PEDS ADMINISTRATION

Answer 7

0.1 to 0.3mg/kg slow (1mg/min) IVP or
0.5mg/kg per rectum (PR)
Titrate IV dose to stop seizure activity or until sedation occurs for cardioversion.
May repeat IVP prn to max
5mg (5 y/o)

Question 8

Onset

Answer 8

1-5min

Question 9

Duration

Answer 9

2-3 hours

Question 10

What gauge IV and what site?

Why?

Answer 10

Largest bore IV in a large vein and run wide open while administering med

May develop phlebitis, sclerosis or thrombosis of vein

Question 11

What should be monitored?

Answer 11

Respiration a

Question 12

What does it precipitate with?

Answer 12

D5W

Question 13

Why should it be injected as close to IV site as possible?

Answer 13

Easily absorbed by plastic

Question 14

Why slow in geriatrics?

Answer 14

Geriatrics may have increased incidence of adverse effects

Question 15

What is the antidote for resp depression?

Answer 15

Romazicon (flumazenil)

Question 16

Supplied?

Answer 16

10mg / 2ml predicted syringe or vial

Question 17

What schedule?

Answer 17

Schedule IV

Question 18

Adverse effects

Answer 18

CARDIO- bradycardia, tachycardia, hypotension
RESP- depression/hypoventilation, apnea
NEURO- dizziness, confusion, blurred vision, restlessness, slurred speech
OTHER- worsens glaucoma, phlebitis

Question 19

Administration

Answer 19

5-10mg slow (5mg/min) IVP
Titrate to stop seizure activity or until sedation occurs for cardioversion.
May repeat 5mg/min to max 20mg

Question 20

PEDS ADMINISTRATION

Answer 20

0.1 to 0.3mg/kg slow (1mg/min) IVP or
0.5mg/kg per rectum (PR)
Titrate IV dose to stop seizure activity or until sedation occurs for cardioversion.
May repeat IVP prn to max
5mg (5 y/o)

Question 21

Onset

Answer 21

1-5min

Question 22

Duration

Answer 22

2-3 hours

Question 23

What gauge IV and what site?

Why?

Answer 23

Largest bore IV in a large vein and run wide open while administering med

May develop phlebitis, sclerosis or thrombosis of vein

Question 24

What should be monitored?

Answer 24

Respiration a

Question 25

What does it precipitate with?

Answer 25

D5W

Question 26

Why should it be injected as close to IV site as possible?

Answer 26

Easily absorbed by plastic

Question 27

Why slow in geriatrics?

Answer 27

Geriatrics may have increased incidence of adverse effects

Question 28

What is the antidote for resp depression?

Answer 28

Romazicon (flumazenil)

Question 29

Supplied?

Answer 29

10mg / 2ml predicted syringe or vial

Question 30

What schedule?

Answer 30

Schedule IV