Diffusion And Osmosis Flashcards
What explains the additional structural components in the lipid bilayer that assists in transport of water soluble compounds, such as glucose and amino acids across the plasma membrane?
Fluid mosaic model of plasma or cell membrane
What is the movement of large molecules across but not through the cell membrane?
Vesicular transport
What is the random movement of molecules or ions or small particles in solution toward a uniform distribution throughout available volume?
Simple diffusion
Is simple diffusion passive or active transport?
Passive transport
What is the principle driving force for passive diffusion of an uncharged solute across the plasma membrane
The difference in concentration
Net flux of a molecule is directly proportional to?
The size of the chemical driving force (concentration gradient)
If an ion is involved, the met flux is proportional to both what?
The chemical and electrical driving forces (electrochemical gradient)
Describe Fick’s law
Rate of diffusion across a plane is proportional to the concentration gradient across the plane and to the area of the plane
What causes the diffusion constant to decrease?
Increase in size of the molecule
Decrease in solution temperature
Increase in viscosity of solvent
What has the strongest influence on permeability?
Lipid solubility, because most substances in body are hydrophilic and don’t easily cross lipid bilayer
What factors are included in the permeability coefficient (P)?
Membrane thickness, diffusion coefficient of solute within membrane, solubility of the solute in membrane
What affect does molecule size have on permeability?
The smaller the molecule the faster it penetrates
An electrical potential difference across a cell membrane will cause?
Movement of ions even if there is not a concentration gradient
Describe osmosis
Movement of water across cell membranes
What is the driving force for osmosis?
Osmotic pressure difference acorns cell membrane