Diffusion And Osmosis Flashcards

1
Q

What explains the additional structural components in the lipid bilayer that assists in transport of water soluble compounds, such as glucose and amino acids across the plasma membrane?

A

Fluid mosaic model of plasma or cell membrane

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2
Q

What is the movement of large molecules across but not through the cell membrane?

A

Vesicular transport

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3
Q

What is the random movement of molecules or ions or small particles in solution toward a uniform distribution throughout available volume?

A

Simple diffusion

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4
Q

Is simple diffusion passive or active transport?

A

Passive transport

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5
Q

What is the principle driving force for passive diffusion of an uncharged solute across the plasma membrane

A

The difference in concentration

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6
Q

Net flux of a molecule is directly proportional to?

A

The size of the chemical driving force (concentration gradient)

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7
Q

If an ion is involved, the met flux is proportional to both what?

A

The chemical and electrical driving forces (electrochemical gradient)

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8
Q

Describe Fick’s law

A

Rate of diffusion across a plane is proportional to the concentration gradient across the plane and to the area of the plane

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9
Q

What causes the diffusion constant to decrease?

A

Increase in size of the molecule
Decrease in solution temperature
Increase in viscosity of solvent

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10
Q

What has the strongest influence on permeability?

A

Lipid solubility, because most substances in body are hydrophilic and don’t easily cross lipid bilayer

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11
Q

What factors are included in the permeability coefficient (P)?

A

Membrane thickness, diffusion coefficient of solute within membrane, solubility of the solute in membrane

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12
Q

What affect does molecule size have on permeability?

A

The smaller the molecule the faster it penetrates

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13
Q

An electrical potential difference across a cell membrane will cause?

A

Movement of ions even if there is not a concentration gradient

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14
Q

Describe osmosis

A

Movement of water across cell membranes

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15
Q

What is the driving force for osmosis?

A

Osmotic pressure difference acorns cell membrane

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16
Q

Osmosis occurs from a solution of _______ to ______

A

High water concentration to low water concentration

17
Q

Does water move up or down its concentration gradient during osmosis?

A

Down

18
Q

Osmotic pressure is determined by?

A

Number of particles dissolved in a solution (the concentration of all solutes)

19
Q

What does the Van’t Hoff equation calculate?

A

Osmotic pressure in biological systems

20
Q

Osmotic pressure of a solution is directly proportional to?

A

The osmotic ally effective concentration or osmolar concentration

21
Q

The osmolarity of a solution is determined by?

A

The concentration of osmotically active particles

22
Q

Water is in steady state balance across cell membranes only when?

A

Osmolality inside and outside the cell is the same

23
Q

What is the effect of ADH?

A

Renal retention of water and vascular smooth muscle contraction

24
Q

Define isoosmotic

A

Total osmotic pressure of solution is equal to that of the cell or another solution (no water movement in or out of cell)

25
Q

Define hyperosmotic

A

Solution has greater osmotic pressure than the cell or another solution (water moves out of cell and cell shrinks in volume) ICF volume decreases

26
Q

Define hypoosmotic

A

If the solution has less osmotic pressure than the cell or another solution (water moves into cell and swells in cell volume)

27
Q

Permeant changes are?

A

Temporary changes in osmotic pressure

28
Q

Transient changes in cell volume occur via?

A

Response to changes in extracellular concentration of permeant solutes

29
Q

Adding a permeant solute such as urea or glycerol to ECF will do what?

A

Increase ECF osmolality

30
Q

What is the must abundant lipid in the membrane of cells?

A

Phospholipids