digestion Flashcards
what is digestion
the process in which large, complex molecules are hydrolysed into smaller, soluble molecules that can be absorbed across cell membranes
what are the two types of amylase and where are they found
salivary amylase - in mouth
pancreatic amylase - in small intestine
what is maltase and what does it digest
membrane bound enzymes
hydrolyse disaccharides into monosaccharides
what molecules are absorbed by co transport
glucose and amino acids
what do amylases digest
starch into maltose by hydrolysing glycosidic bonds
describe the mechanism of cotransport
- sodium ions are actively transported out of epithelial cells into blood to provide concentration gradient
- this allows sodium ions to diffuse from lumen into epithelial cells by facilitated diffusion
- glucose / amino acid is taken with the sodium ion as it diffuses, in a specific carrier protein
- glucose / amino acid exits cell into blood down a concentration gradient via facilitated diffusion
what are endopeptidases
found in the stomach / ileum
hydrolyse peptide bonds between amino acids in the central region of a polypeptide
forming shorter polypeptides
what are exopeptidases
found in the ileum
hydrolyse peptide bonds between terminal amino acids
forming dipeptides / amino acids
what are dipeptidases
membrane bound enzymes
hydrolyse peptide bonds in dipeptides
forming amino acids
what is the emulsification of lipids
bile salts break large lipid droplets into smaller ones, increasing the surface area
what do lipases do
hydrolyse ester bonds in triglycerides
forming fatty acids, glycerol, monoglycerides
how are lipids absorbed
- bile salts stay associated with products of digestion forming micelles
- micelles transport contents to epithelial cells where they dissociate
- the non-polar products diffuse simply across the cell surface membrane
- once inside, the smooth endoplasmic reticulum and golgi apparatus reform triglycerides, forming chylomicrons
- chylomicrons are transported into lacteals via exocytosis before entering the blood