digestive system Flashcards

(82 cards)

1
Q

what is the main function of digestive system?

A

– Take in food
– Break it down into nutrient molecules
– Absorb molecules into the bloodstream
– Rid body of any indigestible remains

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2
Q

what are the 2 groups of the digestive system?

A

-– Alimentary canal (gastrointestinal or G I tract or gut)
- – Accessory digestive organs

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3
Q

– Alimentary canal (gastrointestinal or G I tract or gut) function

A

 Continuous muscular tube that runs from the mouth to anus
 Digests food: breaks down into smaller fragments
 Absorbs fragments through lining into blood
 Organs: mouth, pharynx, esophagus, stomach, small intestine, large intestine, anus

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4
Q

– Accessory digestive organs

A

 Teeth
 Tongue
 Gallbladder
 Digestive glands: produce secretions that help break down foodstuffs
– Salivary glands
– Liver
– Pancreas

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5
Q

what is digestion?

A

-Eating

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6
Q

what is propulsion?

A
  • movement of food through the alimentary canal, which includes:
     Swallowing
     Peristalsis: major means of propulsion of food that involves alternating waves of contraction and relaxation
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7
Q

what is mechanical breakdown?

A
  • includes chewing, mixing food with saliva, churning food in stomach, and segmentation
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8
Q

what is segmentation?

A
  • local constriction of intestine that mixes food with digestive juices
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9
Q

what is digestion?

A

series of catabolic steps that involves enzymes that break down complex food molecules into chemical building blocks

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10
Q

what is absorption?

A

passage of digested fragments from lumen of G I tract into blood or lymph

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11
Q

what is defecation?

A

elimination of indigestible substances via anus in form of feces

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12
Q

what is peritoneum?

A

serous membranes of abdominal cavity

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13
Q

what is visceral peritoneum?

A

membrane on external surface of most digestive organs

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14
Q

what is parietal peritoneum?

A

membrane that lines body wall

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15
Q

what peritoneal cavity?

A

– Fluid-filled space between two peritoneums
– Fluid lubricates mobile organs

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16
Q

what is mesentery?

A

double layer of peritoneum; layers are fused back to back
– Extends from body wall to digestive organs
– Provides routes for blood vessels, lymphatics, and nerves
– Holds organs in place and also stores fat

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17
Q

what is intraperitoneal (peritoneal) organs?

A

organs that are located within the peritoneum

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18
Q

what are retroperitoneal organs?

A

located outside, or posterior to, the peritoneum
– Includes most of pancreas, duodenum, and parts of large intestine

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19
Q

what is peritonitis?

A

– Inflammation of peritoneum
– Can be caused by piercing abdominal wound, perforating ulcer, or ruptured appendix
– Peritoneal coverings stick together, which helps localize infection
– Dangerous and lethal if it becomes widespread
– Treatment: debris removal and megadoses of antibiotics

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20
Q

what are the 4 layers all digestive organs have?

A

– Mucosa
– Submucosa
– Muscularis externa
– Serosa

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21
Q

what is mucosa?

A

– Tunic layer that lines lumen
– Functions: different layers perform one or all three
 Secretes mucus, digestive enzymes, and hormones
 Absorbs end products of digestion
 Protects against infectious disease

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22
Q

what are the sublayers of mucosa?

A

 Epithelium
 Lamina propria
 Muscularis mucosae

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23
Q

what is epithelium and its function?

A

 Simple columnar epithelium and mucus-secreting cells in most of tract
– Mouth, esophagus, and anus are made up of stratified squamous epithelium
 Secretes mucus
– Protects digestive organs from enzymes
– Eases food passage
 May secrete enzymes and hormones (e.g., in stomach and small intestine)

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24
Q

what is lamina propria?

A

 Made up of loose areolar connective tissue
 Rich supply of capillaries located here
– Needed for nourishment and absorption
 Also contains lymphoid follicles that help defend against microorganisms
– Follicles are part of M A L T (mucosa-associated lymphoid tissue)

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25
what is muscularis mucosae?
 Smooth muscle that produces local movements of mucosa
26
what is submucosa?
– Consists of areolar connective tissue – Contains blood and lymphatic vessels, lymphoid follicles, and submucosal nerve plexus that supply surrounding G I tract tissues – Has abundant amount of elastic tissues that help organs to regain shape after storing large meal
27
what is muscularis externa?
– Muscle layer responsible for segmentation and peristalsis – Contains inner circular muscle layer and outer longitudinal layers  Circular layer thickens in some areas to form sphincters
28
what is serosa?
– Outermost layer, which is made up of the visceral peritoneum  Formed from areolar connective tissue covered with mesothelium (single layer of squamous epithelium) in most organs  Replaced by fibrous adventitia in esophagus – Dense connective tissue that holds esophagus to surrounding structures  Retroperitoneal organs have both an adventitia and a serosa
29
what does splanchnic circulation include?
– Arteries that branch off aorta to serve digestive organs  Hepatic, splenic, and left gastric arteries  Inferior and superior mesenteric arteries – Hepatic portal circulation  Drains nutrient-rich blood from digestive organs  Delivers blood to liver for processing
30
what is enteric nervous system?
G I tract nervous system and it is also called gut brain.
31
gut brain
* Gut brain is made up of enteric neurons that communicate extensively with each other – Major nerve supply to G I tract wall that controls motility – Enteric neurons make up bulk of two main interconnecting intrinsic nerve plexuses: – Submucosal nerve plexus  Regulates glands and smooth muscle in mucosa – Myenteric nerve plexus  Controls G I tract motility
32
what is short flexes?
mediated by enteric nerve plexuses (gut brain); respond to stimuli in G I tract
33
what is long reflexes?
respond to stimuli arising inside or outside of gut, such as from autonomic nervous system  Parasympathetic system enhances digestive process  Sympathetic system inhibits digestion
34
3 key concepts to regulate G I activity?
digestive, effector and neurons activity
35
what is digestive activity?
* Digestive activity is provoked by a range of mechanical and chemical stimuli – Receptors located in walls of G I tract organs – Respond to stretch, changes in osmolarity and p H, and presence of substrate and end products of digestion
36
what is effector of digestive activity?
* Effectors of digestive activity are smooth muscle and glands – When stimulated, receptors initiate reflexes that stimulate smooth muscle to mix and move lumen contents – Reflexes can also activate or inhibit digestive glands that secrete digestive juices or hormones
37
what is neuron digestive activity?
* Neurons (intrinsic and extrinsic) and hormones control digestive activity – Nervous system control  Intrinsic controls: involve short reflexes (enteric nervous system)  Extrinsic controls: involve long reflexes (autonomic nervous system) – Hormonal controls  Hormones from cells in stomach and small intestine stimulate target cells in same or different organs to secrete or contract
38
what are the associated organs with mouth?
* Associated organs include: – Mouth – Tongue – Salivary glands – Teeth
39
what is mouth?
* Also called the oral (buccal) cavity – Bounded by lips anteriorly, cheeks laterally, palate superiorly, and tongue inferiorly – Oral orifice is the anterior opening – Walls of mouth lined with stratified squamous epithelium  Tough cells that resist abrasion  Cells of gums, hard palate, and part of tongue are keratinized for extra protection
40
lips and cheeks
– Lips (labia): composed of fleshy orbicularis oris muscle – Cheeks: composed of buccinator muscles – Oral vestibule: recess internal to lips and cheeks, external to teeth and gums – Oral cavity proper: lies within teeth and gums – Labial frenulum: median attachment of each lip to gum
41
what is palate?
– Palate forms the roof of the mouth and has two distinct parts
42
what is hard palate?
formed by palatine bones and palatine processes of maxillae with a midline ridge called raphe – Mucosa is slightly corrugated to help create friction against tongue
43
what is soft palate?
fold formed mostly of skeletal muscle – Closes off nasopharynx during swallowing – Laterally, soft palate anchored to tongue by palatoglossal arches – Also anchored to wall of oropharynx by palatopharyngeal arches – Area in between two arches is called fauces * Palatine tonsils are located in fauces
44
what is uvula?
: fingerlike projection that faces downward from free edge of soft palate
45
tongue and its function
* Tongue occupies floor of mouth * Composed of interlacing bundles of skeletal muscle * Functions include: – Gripping, repositioning, and mixing of food during chewing – Formation of bolus, mixture of food and saliva – Initiation of swallowing, speech, and taste * Intrinsic muscles change shape of tongue * Extrinsic muscles alter tongue’s position
46
what is lingual frenulum?
attachment to floor of mouth * Superior surface bears papillae, peglike projections of underlying mucosa
47
what is filiform papillae?
gives tongue roughness to provide friction; only one that does not contain taste buds; gives tongue a whitish appearance
48
what is fungiform papillae
mushroom shaped, scattered widely over tongue; vascular core causes reddish appearance of tongue
49
what is vallate (circumvallate) papillae?
: 8–12 form V-shaped row in back of tongue
50
what is foliate papillae?
located on lateral aspects of posterior tongue
51
what is terminal sulcus and it function?
groove located posterior to vallate papillae – Marks division between:  Body: portion of tongue that resides in oral cavity  Root: posterior third residing in oropharynx – Does not contain papillae, but still bumpy because of lingual tonsil, which lies deep to its mucosa
52
what is ankyloglossia?
: congenital condition in which children are born with an extremely short lingual frenulum – Often referred to as “tongue-tied” or “fused tongue” – Restricted tongue movement distorts speech – Treatment: surgical snipping of frenulum
53
what is the function saliva?
– Cleanses mouth – Dissolves food chemicals for taste – Moistens food; compacts into bolus – Begins breakdown of starch with enzyme amylase
54
what is minor salivary glands?
are scattered throughout oral cavity; augment slightly.
55
what major salivary glands?
parotid, submandibular, and sublingual?
56
what is parotid?
anterior to ear and external to masseter muscle  Parotid duct opens into oral vestibule next to the second upper molar
57
what is submandibular and its function?
medial to body of mandible  Duct opens at base of lingual frenulum
58
what is sublingual and its function?
: anterior to submandibular gland under tongue  Opens via 10–12 ducts into floor of mouth
59
what is serous cells?
produce watery secretion, enzymes, ions, bit of mucin
60
what is mucous cells function?
produce mucus
61
what is Xerostomia?
dry mouth, uncomfortable condition caused by too little saliva being made
62
what is the composition of saliva?
– Mostly water (97–99.5%), so hypo-osmotic – Slightly acidic (p H 6.75 to 7.00) – Electrolytes: N a+, K+, C l−, P O42−, H C O3− – Salivary amylase and lingual lipase – Proteins: mucin, lysozyme, and I g A – Metabolic wastes: urea and uric acid – Lysozyme, I g A, defensins, and nitric oxide from nitrates in food protect against microorganisms – 1500 m l/day can be produced – Minor glands continuously keep mouth moist
63
– Major salivary glands are activated by parasympathetic nervous system when:
 Ingested food stimulates chemoreceptors and mechanoreceptors in mouth, sending signals to Salivatory nuclei: – Salivatory nuclei in brain stem that stimulate parasympathetic impulses along fibers in cranial nerves VII and IX to glands – Strong sympathetic stimulation inhibits salivation and results in dry mouth (xerostomia) – Smell/sight of food or upset G I can act as stimuli
64
Teeth
* Teeth lie in sockets in gum-covered margins of mandible and maxilla
65
what is mastication?
process of chewing that tears and grinds food into smaller fragments
66
what is the definition and dental formula?
– Primary dentition consists of 20 deciduous teeth, or milk or baby teeth, that erupt between 6 and 24 months of age – 32 deep-lying permanent teeth enlarge and develop while roots of milk teeth are resorbed from below, causing them to loosen and fall out  Occurs around 6–12 years of age – All but third molars (wisdom teeth) are in by the end of adolescence  Third molars may or may not emerge around 17–25 years of age
67
what are the 3 teeth' classified shapes?
– Incisors: chisel shaped for cutting – Canines: fanglike teeth that tear or pierce – Premolars (bicuspids): broad crowns with rounded cusps used to grind or crush  Molars: broad crowns, rounded cusps: best grinders – During chewing, upper and lower molars lock together, creating tremendous crushing force
68
what is the dental formula?
shorthand indicator of number and position of teeth – Shows ratio of upper to lower teeth for only half of mouth; other side is mirror image – Primary – Permanent
69
what is the crown and its function?
exposed part above gingiva (gum) – Covered by enamel, the hardest substance in body * Heavily mineralized with calcium salts and hydroxyapatite crystals * Enamel-producing cells degenerate when tooth erupts, so no healing if tooth decays or cracks; needs artificial repair by filling
70
what is root?
portion embedded in jawbone – Connected to crown by neck – Canines, incisors, and premolars have only one root  First upper premolar often has two – First two upper molars have three roots – First two lower molars have two roots – Third molar roots vary; often single fused root
71
what is cement and its function?
calcified connective tissue – Covers root; attaches it to periodontal ligament
72
what is periodontal ligament?
– Forms fibrous joint called gomphosis – Anchors tooth in bony socket (alveolus)
73
what is gingival sulcus?
: groove where gingiva borders tooth
74
what is dentin?
bonelike material under enamel – Maintained by odontoblasts of pulp cavity
75
what is pulp activity?
surrounded by dentin
76
what is pulp?
connective tissue, blood vessels, and nerves
77
what is root canal?
as pulp cavity extends to root
78
what is apical foramen?
– Entry for blood vessels, nerves, etc.
79
what is impacted tooth?
a tooth that remains trapped in the jawbone * Can cause a good deal of pressure and pain * Wisdom teeth are most commonly involved. * Treatment: surgical removal
80
what is dental caries?
demineralization of enamel and dentin from bacterial action – Dental plaque (film of sugar, bacteria, and debris) adheres to teeth – Acid from bacteria dissolves calcium salts – Proteolytic enzymes digest organic matter – Prevention: daily flossing and brushing
81
what is gingivitis?
– Plaque calcifies to form calculus (tartar) – Calculus disrupts seal between gingivae and teeth – Anaerobic bacteria infect gums – Infection is reversible if calculus removed
82
what is periodontitis?
– Neglected gingivitis can escalate to disease – Immune cells attack not only bacterial intruders, but also body tissues  Can destroy periodontal ligament  Can activate osteoclasts, which leads to dissolving of bone and possible tooth loss – May increase heart disease and stroke two ways:  Promotes atherosclerotic plaque formation  Bacteria entering blood can cause clot formation in coronary and cerebral arteries – Risk factors: smoking, diabetes mellitus, oral piercings