Digestive System Flashcards
Main functions of the Digestive system
–Take in food (Ingestion)
–Break it down into nutrient molecules (Digestion)
–Absorb molecules into the bloodstream (Absorbtion)
–Rid body of any indigestible remains (Defecati
Organs of the digestive system fall into two groups:
Alimentary canal (gastrointestinal or GI tract or gut)
Accessory digestive organs
Gi tract
- Continuous muscular tube that runs from the mouth to anus
- Digests food: breaks down into smaller fragments
- Absorbs fragments through lining into blood
- Organs: mouth, pharynx, esophagus, stomach, small intestine, large intestine, anus
Accessory digestive organs
•Teeth •Tongue •Gallbladder •Digestive glands: produce secretions that help break down foodstuffs –Salivary glands –Liver –Pancreas
Ingestion
Eating
Propulsion
Propulsion: movement of food through the
alimentary canal, which includes:
•Swallowing
Peristalsis
Peristalsis
major means of propulsion of food that involves alternating waves of contraction and relaxation
Mechanical breakdown
includes chewing,
mixing food with saliva, churning food in
stomach, and segmentation
Segmentation
local constriction of intestine that mixes food with digestive juices
Digestion
series of catabolic steps that involves enzymes that break down complex food molecules into chemical building blocks
Absorption
passage of digested fragments from lumen of GI tract into blood or lymph
Defecation
elimination of indigestible substances via anus in form of feces
- Distension initiates spinal defecation reflex
- Parasympathetic signals
- Stimulate contraction of sigmoid colon and rectum
- Relax internal anal sphincter
- Conscious control allows relaxation of external anal sphincter
Appendix
Appendicitis: acute inflammation of appendix; usually results from a blockage by feces that traps infectious bacteria
•Venous drainage can be impaired, leading to ischemia and necrosis (tissue death)
•Ruptured appendix can cause peritonitis
•Symptoms: pain in umbilical region, moving to lower right abdominal quadrant
•loss of appetite, nausea, and vomiting are also seen
•Treatment: surgical removal (appendectomy)
Subdivisions of large intestine
Cecum: first part of large intestine
2. Appendix: masses of lymphoid tissue
•Part of MALT of immune system
•Bacterial storehouse capable of recolonizing gut when necessary
•Twisted shape of appendix makes it susceptible to blockages
Colon: has several regions, most which are
retroperitoneal (except for transverse and
sigmoid regions)
•Ascending colon: travels up right side of abdominal cavity to level of right kidney
•Transverse colon: travels across abdominal cavity
Modifications of small intestine for absorption
- Circular folds
- Villi
- Microvilli
Circular folds
•Permanent folds (~1 cm deep) that force chyme to slowly spiral through lumen, allowing more time for nutrient absorptio
Villi
•Fingerlike projections of mucosa (~1 mm high) with a core that contains dense capillary bed and lymphatic capillary called a lacteal for absorption
Microvilli
•Cytoplasmic extensions of mucosal cell that give fuzzy appearance called the brush border that contains membrane-bound enzymes brush border enzymes, used for final carbohydrate and protein digestion
Small intestine
the major organ of digestion and absorption
Hepatopancreatic sphincter
controls entry of bile and pancreatic juice into duodenum
Digestive enzymes
Proteases (for proteins): secreted in inactive form to prevent self-digestion
•Amylase (for carbohydrates)
•Lipases (for lipids)
•Nucleases (for nucleic acids)
The pancreas
Location: mostly retroperitoneal, deep to greater curvature of stomach
•Head is encircled by duodenum; tail abuts spleen
•Exocrine function: produce pancreatic juice
•Ducts: secrete to duodenum via main pancreatic duct; smaller duct cells produce water and bicarbonate
•Endocrine function: secretion of insulin and glucagon by pancreatic islet cells
The gallbladder
- Gallbladder is a thin-walled muscular sac on ventral surface of liver
- Functions to store and concentrate bile by absorbing water and ions
- Contains many honeycomb folds that allow it to expand as it fills
- Muscular contractions release bile via cystic duct, which flows into bile duct
Hepatitis
•Usually viral infection, drug toxicity, wild mushroom poiso