Digoxin Overdose/Poisoning

Question 1

What are the symptoms of digoxin poisoning. (9)

Answer 1

Drowsiness. 
Confusion (rarely).
Yellow-green visual halos (rarely). 
Diarrhoea. 
Nausea and vomiting. 
Dizziness. 
Anorexia. 
Sinus bradycardia. 
There may be serious tachyarrhythmias.

Question 2

What do you first do if there are serious arrhythmias in the context of digoxin toxicity.

Answer 2

Correct hypokalaemia.

Question 3

When does digoxin toxicity commonly occur.

Answer 3

During chronic administration.

Acute poisoning is infrequent.

Question 4

What are the typical causes of digoxin poisoning. (3)

Answer 4

Usually accidental, arising from:
Prescription of an excessive dose.
Impairment of renal function.
Drug interactions.