Dinitrato de isosorbida Flashcards

(6 cards)

1
Q

MECANISMO DE ACCIÓN

A

Libera óxido nítrico,

y estimula guanilato ciclasa—> vasodilatación

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2
Q

INDICACIONES TERAPÉUTICAS

A

Angina de pecho

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3
Q

FARMACOCINÉTICA

A

A - Sublingial, oral
D - UP: 30%
M - Hígado
E - Riñon

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4
Q

REACCIONES ADVERSAS

A
  • Cefalea
  • Mareo
  • Astenia
  • Hipotensión
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5
Q

INTERACCIONES

A
  • Tadafilo (antihipertensivo, urología)
  • Vardenafilo
  • Sildenafilo (antihipertensivo, urología)
  • Avanafilo
  • Nitroglicerina (rectal)
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6
Q

CONTRAINDICACIONES

A
  • Síncope
  • Anemia grave
  • Traumatismo craneoencefálico
  • Hemorragia cerebral
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