Diphenhydramine Flashcards

1
Q

Benadryl

Class

A
  • Antihistamine
  • Anticholinergic
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2
Q

Benadryl

Mechanism of action

A
  • Blocks cellular histamine receptors
  • Decrease vasodilation
  • Reduce motion sickness
  • Reverse extrapyramidal reactions
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3
Q

Benadryl

Indications

A
  • Symptomatic relief of allergies, allergic reactions & anaphylaxis
  • Acute dystonic reactions (phenothiazines)
  • Motion sickness and hayfever
  • Blood administration reactions
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4
Q

Benadryl

Contraindications

A
  • Asthma
  • Glaucoma
  • Pregnancy
  • Infants
  • PT taking MAOI’s (monamine oxidase inhibitors)
  • HTN
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5
Q

Benadryl

Adverse reactions

A
  • Sedation
  • Hypotension
  • SZ
  • Visual disturbances
  • Paradoxical CNS excitation in children
  • Palpitations and arrythmias
  • Dry mouth and throat
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6
Q

Benadryl

Drug interactions

A
  • Potentiates ETOH and anticholinergics
  • Inhibits corticosteroids
  • MAOI’s may prolong anticholinergic effects
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7
Q

Benadryl

Dosage and administration

A
  • Adult:
    • 25-50mg IM, IV
  • Ped:
    • 1-2 mg/kg slow IV or IM
  • If given PO: 5mg/kg/24 hrs
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8
Q

Benadryl

Duration of action

A
  • Onset: 15-30 min
  • Peak effect: 1 hr
  • **Duration: **3-12 hrs
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9
Q

Benadryl

Special considerations

A
  • Pregnancy: Cat B
  • Not used in infants or in pregancy
  • If used in anaphylaxis, will be used in conjuction with Epi & corticosteroids
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