direct Sympathomimetics

Question 1

acute asthma/COPD

Answer 1

albutarol

Question 2

serial (long-term) asthma/COPD

Answer 2

salmeterol

Question 3

acute bronchospasm in asthma and tocolysis

Answer 3

terbutaline

Question 4

Cardiac stress testing, acute decompensated
heart failure (HF) with cardiogenic shock
(inotrope)

Answer 4

Dobutamine β1 > β2, α

Question 5

Unstable bradycardia, shock; inotropic and
chronotropic effects at lower doses via β effects;
vasoconstriction at high doses via α effects

Answer 5

Dopamine D1 = D2 > β > α

Question 6

Anaphylaxis, asthma, shock, open-angle
glaucoma; α effects predominate at high
doses. Stronger effect at β2-receptor than
norepinephrine.

Answer 6

Epinephrine β > α

Question 7

Postoperative hypertension, hypertensive crisis.
Vasodilator (coronary, peripheral, renal, and
splanchnic). Promotes natriuresis. Can cause
hypotension, tachycardia, flushing, headache

Answer 7

Fenoldopam D1

Question 8

Electrophysiologic evaluation of
tachyarrhythmias. Can worsen ischemia. Has
negligible α effect.

Answer 8

Isoproterenol β1 = β2

Question 9

Autonomic insufficiency and postural
hypotension. May exacerbate supine
hypertension

Answer 9

Midodrine α1

Question 10

Urinary urgency or incontinence or overactive
bladder. Think “mirab3gron.”

Answer 10

Mirabegron β3

Question 11

Hypotension, septic shock

Answer 11

Norepinephrine α1 > α2 > β1

Question 12

Hypotension (vasoconstrictor), ocular procedures
(mydriatic), rhinitis (decongestant), ischemic
priapism

Answer 12

Phenylephrine α1 > α2