Directing Effects of EAS Substituents Flashcards
1
Q
-OR
A
Moderate/strong activator (O/P)
2
Q
-carboxylic acid
A
Moderate deactivator (M)
3
Q
-NO2
A
Strong deactivator (M)
4
Q
-I
A
Weak deactivator (O/P)
5
Q
-CH3
A
Weak activator (O/P)
6
Q
-1° alkyl
A
Weak activator (O/P)
7
Q
-O(-)
A
Strong activator (O/P)
8
Q
-ketone
A
Moderate deactivator (M)
9
Q
-4° alkyl
A
Weak activator (O/P)
10
Q
-NH-carbonyl
A
Moderate activator (O/P)
11
Q
-3° alkyl
A
Weak activator (O/P)
12
Q
-NHR
A
Strong activator (O/P)
13
Q
-SO3H
A
Moderate deactivator (M)
14
Q
-amide
A
Moderate deactivator (M)
15
Q
-aldehyde
A
Moderate deactivator (M)
16
Q
-CN
A
Moderate deactivator (M)
17
Q
-Br
A
Weak deactivator (O/P)
18
Q
-CX3
A
Strong deactivator (M)
19
Q
-OH
A
Strong activator (O/P)
20
Q
-Cl
A
Weak deactivator (O/P)
21
Q
-NR3(+)
A
Strong deactivator (M)
22
Q
-NH2
A
Strong activator (O/P)
23
Q
-NR2
A
Strong activator (O/P)
24
Q
-2° alkyl
A
Weak activator (O/P)
25
-O-carbonyl
Moderate activator (O/P)
26
-NR-carbonyl
Moderate activator (O/P)
