Disease Dilemmas

Question 1

Define infectious

Answer 1

a disease spread by parasites, bateria, viruses, fungi etc.

Question 2

define non-infectious

Answer 2

a non-communicable disease due to age, genetic defects e.g. cancer

Question 3

define communicable

Answer 3

an infectious disease that spreads from host to host

Question 4

define non-communicable

Answer 4

an infectious disease that cannot be spread between people e.g. malaria

Question 5

define contagious

Answer 5

a disease spread by contact or indirect contact between people e.g. Ebola

Question 6

define non-contagious

Answer 6

a disease that cannot be spread by contact between people

Question 7

define epidemic

Answer 7

a disease outbreak that spreads quickly through the population of a geographical area

Question 8

define endemic disease

Answer 8

a widespread occurrence of an infectious disease in a community permanently

Question 9

Define pandemic

Answer 9

an epidemic which spreads worldwide e.g. Spanish flu

Question 10

What are the main patterns of disease?

Answer 10

Non-infectious disease causes most death in developed countries
Increasingly developing countries are being affected
Other disease spread is determined by several factors

Question 11

Define disease diffusion

Answer 11

when a disease is transmitted to a new location. It implies that a disease spreads from a central source.
Diffusion models attempt to show how infection can spread from a central point.

Question 12

define expansion diffusion

Answer 12

from source to new areas

Question 13

define contagious diffusion

Answer 13

infection by direct contact. infection risk is lessened with distance e.g. measles epidemic

Question 14

define hierarchical diffusion

Answer 14

infection spread through a sequence of places e.g. spread of HIV/AIDS from larger to smaller centres in the US.

Question 15

define relocation diffusion

Answer 15

an infection spreads to a new area but leaves its source behind

Question 16

define network diffusion

Answer 16

spread via transport and social networks

Question 17

What does Hagerstrand’s diffusion model examine and what are the main ideas?

Answer 17

Examines probable reasons why a disease spreads
Several ideas:
Neighbourhood effect – unsurprisingly, proximity to carriers affects probability of contraction
Numbers infected in an epidemic shows an S curve over time
Physical barriers interrupt diffusion

Question 18

what are the 4 different stages of the hagerstrand model?

Answer 18

Primary stage - strong contrast in disease incidence between the area of outbreak and remote areas
Diffusion stage - new centres of disease outbreak occur at distance from the source reduing the spatial variation in stage 1
Condensing stage - number of new cases is more equal in all locations, irrespective of distance from the source
Saturation stage - diffusion decelerates as the incidence of disease reaches its peak

Question 19

What are the physical barriers to disease spread

Answer 19

distance, mountains, seas, deserts, climatic change, amount of water stagnant
distance decay –
the further from the source the lower the incidence of disease.
remoteness –
spread into rural peripheries (low pop density, few transport links)/mountainous regions (low pop, few transport links, colder)/extreme climate areas less likely
Mountains, oceans are major natural barriers to diffusion.

Question 20

What are the socio-economic barriers to disease spread?

Answer 20

political border checks, imposition of curfews or quarantining (mostly implemented by international organisations or governments)
management of disease e.g. COVID19, H1N1 people isolated, awareness programmes, hygiene, face masks, cancelling public events, curfews, quarantining etc
mass vaccination, drug provision

Question 21

How do seasonal variations influence disease spread?

Answer 21

Epidemics of influenza etc peak in winter months in northern hemisphere
Temperature - determines rates of vector development, viral replication. Warm (32 degrees), humid (95%) dengue etc
Precipitation - seasonal, ponds/pools for breeding, exceptional events
Diseases are concentrated in humid lowlands
Winter flu - low temperature, humidity
Rainy seasons - vector populations increase
bilharzia - seasonal snail life cycle

Question 22

How does climate change influence the spread of disease

Answer 22

anthrax in Siberian permafrost
brackish water and vibrio vulnificus
increased vector range - WNV, malaria, dengue, lyme, sleeping sickness (WHO 77 million more affected 2090)
vectors mentioned - mosquito, tick, tsetse
may disappear from areas where temperature is too high

Question 23

define zoonotic diseases

Answer 23

disease passed from animals to humans and are caused by bacteria, parasites and fungi
e.g. malaria, sleeping sickness, dengue fever, rabies

Question 24

When can zoonotic diseases increase?

Answer 24

free movement of infected animals
urbanisation creates habitats for animals
closer contact
no vaccination programmes
hygeine/sanitation are poor
prolonged close contact between humans/animals (poultry farms)

Question 25

How does development affect disease spread?

Answer 25

developed countries have better wellbeing and healthcare as well as more money to spend on agriculture, health and infrastructure

Question 26

How does economic development reduce disease spread?

Answer 26

Agriculture investment raises yields and efficiency to provide good quality food improved infrastructure so food can be stored and distributed efficiently and basic services can reach the whole population investment in the health service

Question 27

how does social development reduce disease spread?

Answer 27

better education on sanitation, healthy diet and disease spread advances in medical care and availability of basic medicines and vaccinations better education and more oppotunities to become a healthcare proffesional reduced IMR

Question 28

what is the epidemiological transition model?

Answer 28

suggests that, as a country develops, over time there will be a transition from infectious disease as the main cause of death to chronic and degenerative diseases Omran 1971

Question 29

What are the 4 stages of the ETM?

Answer 29

1. Age of infection and famine 20-40 year LE, poor sanitation and hygeine, bad food supply, infections 2. age of reducing pandemics 30-50 LE, improved sanitation, better diet, reduced infectious increase in strokes/heart disease 3. age of degenerative and human-made diseases 50-60 LE, increased ageing, lifestyles associated with poor diet, less activity and addictions, high BP, obesity, type 2 diabetes etc 4. age of delayed degenerative diseases 70+ LE, reduced risk behaviours, health promotion and new treatment, cancer and strokes can causes, more aeging diseases e.g. dementia

Question 30

how is the ETM contextualised on a global scale (3)

Answer 30

Western/classical model - slow decline in death rate followed by lower fertility accelerated model - falls in mortality are more rapid (Latin America e.g.) contemporary/delayed model - decreases in mortality are not accompanied by decline in fertility e.g. Sub-Saharan Africa

Question 31

Why do ACs have higher levels of non-communicable diseases?

Answer 31

eliminated communicable disease through diagnosis, treatment, high standards of living, clean water and good nutrition prolonged life overnutrition and excess consumption of sugar, fats and salts has increased levels such as CPD and diabetes

Question 32

Why do LIDCs have higher levels of communicable diseases?

Answer 32

overnutrition is becoming a problem as affluence increases - non-communicable increasing geography - tropical and sub-tropical locations cause more communicable disease such as ebola, sleeping sickness etc communicable disease accounts for majority of deaths in poor countries due to poverty, lack of resources, nutritional issues, water pollution, lack of sanitation and hygeine

Question 33

How does increasing global mobility affect disease spread?

Answer 33

leads to wider disease diffusion because of greater international flows of people but improvements in transport and a 'shrinking world' can also cause international organisations to respond rapidly to outbreaks

Question 34

How do international organisations affect disease spread?

Answer 34

predict and mitigate disease WHO, UNICEF, NGOs

Question 35

How does WHO affect disease spread?

Answer 35

1948 194 member states data collection, leadership in health matters, technical support, research and mointoring, publishes world stats annually - allow for planning, funds research projects, emergency aid

Question 36

Covid-19 and disease spread

Answer 36

WHO declared it a pandemic 2020 advised governments to lockdown before vaccinations were available governments responded differently depending on preparedness and previous experience high pop density had worse issues death rates have not always been accurate or available

Question 37

what are the positives of barriers to disease diffusion (physical or soco-economic)

Answer 37

physical barriers isolate communities and reduce the risk of disease spread physical barriers restrict population movements

Question 38

what are the negatives of barriers to disease diffusion (physical or socio-economic)?

Answer 38

isolation may delay medical care arriving lack of contact with other people may reduce immunity large water bodies in certain physical contexts (flood plains) may be more susceptible to flooding, leading to increased waterbourne diseases

Question 39

government mitigation of disease

Answer 39

COVID - WHO 2020 pandemic causes, impacts and responses varied globally due to government decisions and ability of nations to take action quarantine, vaccination, masks, public information and government announcements, LFTs and PCRs, global cooperation in scientific research and development

Question 40

how can medicines from nature be used to prevent disease spread and example?

Answer 40

many modern medications originate from wild plants and natural sources for example: morphine dried latex from seed pods of several species of opium poppy deep, clay-loam, well-drained solid rich in humus pH 6-7.5 clear sunny days with temperatures 30-38 degrees. susceptible to frost and wet weather pain reliever warm, humid conditions.

Question 41

what are the conservation issues relating to the international trade in medicinal plants?

Answer 41

- mainly derived from wild populations, many of which are extinct (reliance is greater in developing countries 80%) - habitat destruction (deforestation), rainforests contain 70% terrestrial plant species, only 1% screened - we are too late? - concerns over biopiracy - pharmaceutical companies need to work with local people in return for conservation profits can fund community projects - sourcing supplies unsustainable - over-harvesting - slow-growing plants and some are grown in niche environments - 4000 threatened

Question 42

what are global scale strategies for disease eradication?

Answer 42

campaigns have had limited impact apart from smallpox eradication 1980 current focus on polio and guinea worm

Question 43

what are national campaigns for disease eradication?

Answer 43

'top-down' malaria 1948-51 government campaign - Mauritius became malaria free but reintroduced by migrant workers - further initiatives - spraying mosquito breeding sites and giving anti-malaria drugs - remains malaria free due to airport screening and spraying

Question 44

what are some local campaigns (grassroots strategies) associated with disease eradication?

Answer 44

- local communities often resist top-down strategies - grassroots strategies - small, community-based projects that focus on need of people and favoured by NGOs - education, assistance and engagement of local people, empower locals (women) Guinea worm - first parasitic disease set for eradication: - diagnosis is easy (visual), intermediate host restricted to stagnant water, simple and cheap intervention, limited geographical distribution GHANA - Ghana Red Cross Women's clubs has eradicated it: - women volunteered to be taught how it is transmitted and how to prevent it - volunteers educated locals - volunteers reported all new cases, distribute and replace water filters, identify water sources used by community and treat them

Question 45

what is the role of women in grassroots strategies to combat disease risk?

Answer 45

huge - often primary carers for kids and key to vaccination and health awareness programmes - female front line health workers seen to have greater impact than male counterparts because they can engage and relate with other women more e.g. understand sourcing water and cleaning it - may play a specific role where a disease is passed on through pregnancy e.g. Zika - in many societies - women have primary responsibility for maintaining hygiene in home and food preparation - can prevent disease spread