Disease of Salivary Glands Flashcards
(15 cards)
What are the two types of acini in normal salivary gland tissue?
Serous acini and mucous acini with excretory ducts.
What is a key microscopic feature of Pleomorphic Adenoma at low power?
A well-circumscribed, encapsulated tumor mass with variable microscopic patterns.
What cellular elements are seen in Pleomorphic Adenoma?
Chondroid material, ductal epithelium, myoepithelial cells, tubular and acinar structures, and myxoid stroma.
What pattern is typical in Basal Cell Adenoma?
Cords of basaloid cells in a trabecular pattern; jigsaw puzzle-like basaloid cell nests.
What characterizes Canalicular Adenoma?
Chains of columnar epithelial cells with tubules and duct-like forms.
What histological feature is seen in Warthin’s tumor?
Papillary cystic tumor with bilayered oncocytic epithelium and lymphoid stroma.
What cell type predominates in Acinic Cell Carcinoma?
Granular, basophilic serous acinar cells.
What are the four cell types in Acinic Cell Carcinoma?
Acinar, clear/vacuolated, intercalated duct-like, and non-specific glandular cells.
What distinguishes low-grade Mucoepidermoid Carcinoma?
Large mucous cells surrounding a cystic space.
What features define high-grade Mucoepidermoid Carcinoma?
Solid sheets of epidermoid and intermediate cells with atypia and brisk mitosis.
What is a hallmark of Adenoid Cystic Carcinoma?
Cribriform and tubular structures with mucopolysaccharide-filled spaces and hyalinized material.
What indicates malignancy in Carcinoma ex Pleomorphic Adenoma?
Pleomorphic epithelial cells with malignant features alongside benign plasmacytoid myoepithelial cells.
What are the histological features of Sjogren’s syndrome?
Intense lymphocytic infiltration and preserved lobular architecture.
What is a Mucocele?
A mucous extravasation or retention cyst caused by saliva leakage or duct obstruction.
What is seen in Necrotizing Sialometaplasia?
Squamous metaplasia of salivary ducts with mucous cells.
