Diseases List Flashcards
(35 cards)
AIDS
HIV
- RNA (retrovirus)
- lysogeny
- gp120 attach to CD4+
- vacc: NONE, but ideally.. inihibitors of..
- reverse transcriptase
- protease
- integrase
- infect as “dsDNA provirus” (lysogeny)
- risk: pregnant patients
Zika
Zika virus
- pregnancy risk
- low mortality
- trans: mosquitos (aedes aegypti); STD; parenteral
- vacc: NONE
- microcephaly; Barre
Polio
poliomyelitis
- enterovirus
- trans: fecal-oral
- viremia, sore throat
- next to eradiacte
Mumps
Mumps virus
- target: lymphocytes
- orchitis (testes)
- meningitis
- swelling glands
Mono/Epstein-Barre
HSV-4
- Viral hepatitis
- Burkitt’s Lymphoma
- enlarged lymph node/spleen
Coccidiodomycosis/Valley Fever
C. arthroconodia
- airborne/systemic mycosis
- dimorphic
- inhalation of dust
Pneumocystis
P. jiroveci
- risk: immunocompromised patients
- opportunistic
Aspergillosis
A. fumigatus
- opportunistic
- risk: HIV patients
- lungs fill w/myecelia => Pulmonary Infection
Kaposi’s Sarcoma
HHV-8
- oncogenic
- risk: immunocompromised patients
Measles
- respiratory droplet
- Subacute Sclerosing Panencephalitis
- CNS degeneration
Trypanosomes
Chagas’/African Sleeping Sickness
- “true” protists
- flagellated
- vacc: NONE
- antigenic shift: accumulate mutations, change protein
- cysts
T. cruzi (Chagas’)
- kissing bug/triatome bug
T. gambiense/rhodesiense (ASS)
- tsetse flies
Candidiasis
C. albicans
- normal flora!
- dimorphic
- opportunistic
- risk: children; brushing mouth
Giardia
G. intestinalis
- flagellated
- ingestion
- diarrhea
- attach to intestinal epithelium
- interfere w/nutrient absorption => malnutrition
Chickenpox/Shingles
HSV-3
- droplet inhalation
- Chickenpox: conjunctiva, resp. mucous (Chickenpox)
- Shingles - latent stage, contagious
Toxoplasmosis
T. gondii
- cyst forming
- trans: fecal-oral, STD
- oocyst in feces
- ingestion
- risk: pregnancy, AIDS patients
CJD/Kuru
- cause of infection: proteins
- NO nucleic acids
- canabolism
- sporadic stage (85%)
- Eating cow meat infected w/Mad Cow => vCJD
- vCJD (progressive dementia, speech abnormality)
Cyclospora
C. cayentanesis
- ingestion
- diarrhea
Cryptococcosis
C. parvum
- airborne/systemic mycoses
- inhale pigeon droppings
- risk: pneumonia; HIV patients
Leishmaniasis
L. donovani
- sandflies
- slow-healing ulcers
- lifetime immunity
Keratitis
acanthameoba
- water borne (tap water)
- diarrhea
Tineas
- cutaneous mycosis
- direct contact
- T. capitis (hair)
- T. pedis (Athlete’s foot)
- T. unguium (nailbed)
- T. cruris (Jock itch)
Rubella
German measles virus
- risk: pregnant patients
- respiratory droplets
- Congenital Rubella Syndrome
Ebola
- trans: direct contact
- high mortality (80%)
HSV-1/HSV-2
- DNA
HSV-1 (Cold Sore)
HSV-2 (Genital Herpes)
- risk: pregnant patients