Diseases Of Skin

Question 1

What is Christ - Siemen’s Tourian Syndrome?

Answer 1

Type I : Hyponidrotic form of
Ectodermal Dysplasia.

3 H seen here
• Hypohydrosis
• Hypotrichasis
• Hypodontia

Question 2

Genetic nature of Christ - Siemens Tourian
Syndrome

Answer 2

X- linked recessive disorder.

Question 3

Only condition where Anodontia is seen is

Answer 3

Ectodermal Dysplasia (although very rarely)

Question 4

What is Lyon’s hypothesis /
Lyonization

Answer 4

It is a hypothesis for any
✗ -linked recessive
disorder

Question 5

Genetic nature of Psoriasis

Answer 5

Auto immune skin
disease

Question 6

What is Koebner’s phenomenon

Answer 6

Aka Isomorphic effect

→ trauma induced lesion
formation

(also seen in lichen Planus but is characteristic of
Psoriasis)

Question 7

What is AUSPITZ’s Sign

Answer 7

Seen with psoriasis

pinpoint bleeding spots
when silvery white scale is removed.

Question 8

Which is the sign that shows

pinpoint bleeding spots
when silvery white scale is removed..

And is seen with which condition.

Answer 8

AUSPITZ’s Sign seen in psoriasis

Question 9

Histopathology of psoriasis shows

Answer 9

test tube shaped rete ridges

Is also seen with:
Gingival fibromatosis and
Drug induced gingival enlargement

Question 10

-Test tube shape Rete Ridges
Shape seen with

Answer 10

• Psoriasis
• Gingival fibromatosis
• Drug induced gingival
enlargement

Question 11

What are Munro’s micro abscess

Answer 11

Intra epithelial micro abscess
Seen in psoriasis

Question 12

What is Psoriasiform lesion

Answer 12

Geographic tonge
• Not related to Psoriasis.

Question 13

LICHEN PLANUS
• first described by

Answer 13

Erasmus Wilson

Question 14

Genetic nature of

LICHEN PLANUS

Answer 14

Auto immune
(T- lymphocyte mediated)

Question 15

What is Grinspan Syndrome

Answer 15

lichen Planers + Diabetes Mellitus + Hypertension

Question 16

What is Greenspan lesion

Answer 16

Is another name for Oral Hairy leukoplakia.

Not related to lichen Planus

Question 17

Whicham’s striae /
honitons lace

Answer 17

.. seen ONLY in lichen
Planus.

Question 18

Whicham’s striae baker.

Answer 18

honitons lace
seen ONLY in lichen
Planus.

Question 19

honitons lace
Aka

Answer 19

Whicham’s striae

seen ONLY in lichen
Planus.

Question 20

Which is the most common clinical type of lichen plants

Answer 20

Reticular lichen planus

Question 21

What is the confirmatory diagnosis of lichen Planus.

Answer 21

DIF
Direct immuno flourescence

(DIF can be done for an
autoimmune disease)

Question 22

Saw tooth Rete pegs seen in

Answer 22

Hypertrophic lichen Planus

Question 23

Max-Jacob /Max-Joseph
space seen in

Answer 23

Hypertrophic lichen Planus

between the epithelium and connective tissue

Question 24

Which type of lichen Planus is a premalignant condition

Answer 24

Erosive lichen planus

(here squamous cell carcinoma eventually develops)

Question 25

Genetic nature of PEMPHIGUS

Answer 25

' Autoimmune

Question 26

cerebriform tongue seen with

Answer 26

Pemphigus vegetans

Question 27

Histopathology of Pemphigus shows:

Answer 27

Tzank cells

Question 28

Tzank test is done for diagnosis o

Answer 28

① Pemphigus ② Herpes simplex

Question 29

DIF (direct immunofluorescence) of Pemphigus shows

Answer 29

IgG in the Intercellular area with Chicken wire pattern or fish net pattern.

Question 30

Chicken wire pattern or fish net pattern seen in the histopathology of

Answer 30

DIF (direct immunofluorescence) of Pemphigus

Question 31

Treatment of Pemphigus

Answer 31

Pulse Therapy → DCP pulse therapy (Dexamethasone cyclophosphamide) [DCP can cause testicular diseases in males and hence Azathioprine is used instead]

Question 32

Nikolsky's sign seen in

Answer 32

Pemphigus

Question 33

Asboe Hansen sign Aka and seen in

Answer 33

Nikolsky's sign seen in Pemphigus

Question 34

Pemphigus foliaceus aka brazilian wildfire

Answer 34

brazilian wildfire

Question 35

brazilian wildfire aka

Answer 35

Pemphigus foliaceus

Question 36

pemphigus erythematosus aka

Answer 36

Senear- usher - syndrome

Question 37

Senear- usher - syndrome aka

Answer 37

pemphigus erythematosus

Question 38

Hailey Hailey disease aka

Answer 38

familial benign Pemphigus

Question 39

familial benign Pemphigus aka

Answer 39

Hailey Hailey disease

Question 40

Genetic nature of PEMPHIGOID

Answer 40

Autoimmune (Ig G4)

Question 41

DIF in PEMPHIGOID shows

Answer 41

deposition of IG g and C 3 in the basement membrane zone in Linear pattern.

Question 42

Stevens Johnson syndrome aka

Answer 42

Erythema Multiforme major

Question 43

Erythema Multiforme major aka

Answer 43

Stevens Johnson syndrome

Question 44

Lyell's disease aka

Answer 44

TENS (toxic epidermal necrolysis)

Question 45

Target-like/Iris/ bulls eye lesions seen in

Answer 45

Erythema Multiforme

Question 46

BLOODY ENCRUSTATIONS seen on lips in

Answer 46

Erythema Multiforme