Disorders of Cranial Nerves Flashcards

(45 cards)

1
Q

What are the Functions of the Cranial Nerves?

A
  • Special” senses
  • “Ordinary” sensation
  • Control of muscle activity
  • Autonomic functions
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2
Q

What are the special sense?

A

Olfaction (I)

Vision (II)

Taste (VII, IX and X)

Hearing - and balance (VIII)

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3
Q

What is responsible for ordinary sensation?

A

Mainly the Vth (trigeminal nerve)

The ear from the VIIth (facial) and IXth (glossopharyneal) nerves

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4
Q

What is in control of msucle activity?

A

Eye muscles – III (oculomotor), IV (trochlear) and VI (abducence) (LR6,SO4, rest 3)

Muscles of mastication – V (trigeminal)

Muscles of facial expression – VII (facial)

Muscles of larynx and pharynx – mainly X (vagus)

Sternomastoid and trapezius muscles - XI (accessory)

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5
Q

What are the autonomic functions
(all parasympathetic) and what is respobisble for them?

A

Pupillary constriction – III (oculomotor)

Lacrimation – VII (facial)

Salivation – submandibular and sublingual glands – VII (facial)

Salivation – parotid gland - IX (glossopharyngeal)

Vagal (X) input to organs in thorax and abdomen

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6
Q

What is used to test CN I - Olfactory?

A

smell – unilateral or bilateral loss

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7
Q

What is used to test CN II – Optic?

A

visual acuity

visual fields

pupillary reactions

fundoscopy

colour vision

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8
Q

What dow e test in CN III, IV and VI – oculomotor, trochlear and abducence?

A

any evidence of ptosis?

pupil of equal size?

pupillary reactions

eye movements – vertical and horizontal

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9
Q

What do we for for in regards to CN V – Trigeminal?

A

sensation in the ophthalmic, maxillary and mandibular divisions

power in the muscles of mastication

corneal reflex

•aw jerk

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10
Q

What do we test for in CN VII – Facial?

A

Muscles of facial expression

Corneal reflex

Taste

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11
Q

What do we test for in CN VIII – Vestibulocochlear nerve?

A

Hearing using Rinne’s and Weber’s tests

Vestibular function using Dix-Hallpike manoevre and Untenberger’s test

(untenbergers test – close eyes and march on spot and will start to turn to side that is dyfunctioning and need to go to ENT clinic)

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12
Q

What do we test for in CN IX (glossopharyngeal) and CN X (vagal)?

A

movement of the palate

gag reflex

quality of speech

quality of cough

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13
Q

WHat do we test for in CN XI – Accessory nerve?

A

Head turning and shoulder shrugging - sternomastoid and trapezius function

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14
Q

How is CN XII – Hypoglossal nerve tested?

A

Appearance, movement and power of tongue

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15
Q

What cranial nerves are responsible for:

Pupillary light reaction

A

afferent – II ; efferent – III

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16
Q

What cranial nerves are responsible for:

Corneal reflex

A

afferent – V ; efferent – VII

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17
Q

What cranial nerves are responsible for:

jaw jerk

A

afferent and efferent – V

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18
Q

What cranial nerves are responsible for:

gag reflex

A

afferent – IX ; efferent - X

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19
Q

III and IV (Oculomotor and Trochlear) nuclei lie in the ________

20
Q

V, VI AND VII (Trigeminal, Abducent and Facial) lie in the ______

21
Q

VIII (Vestibulocochlear) lie at the __________ junction

A

PONTOMEDULLARY

22
Q

IX, X XI and XII (Glossopharyngeal, Vagus, Accessory and Hypoglossal ) lie in the ________

23
Q

What may be some Combinations of Cranial Nerve Signs?

A

Bilateral III - midbrain

III +IV+VI - superior orbital fissure

VI +VII -pons

V + VIII - cerebellopontine angle

Unusual combinations - ?chronic or malignant meningitis

Pure motor signs - ?myasthenia gravis - affects neuromuscular junction

24
Q

What different ways can cranial nerves be damaged?

A

within the brain - e.g. by ischaemia, tumour

crossing the sub-arachnoid space - e.g by meningitis

outside the skull e.g. by base of skull tumours arising in nasopharynx

25
What is optic neuritis?
demyelination within the optic nerve an inflammation that damages the optic nerve
26
What are the signs and symptoms of optic neuritis?
monocular visual loss pain on eye movement reduced visual acuity reduced colour vision optic disc may be swollen often associated with multiple sclerosis
27
How does parasympathetic effect pupillary response?
constriction of the pupil loss of parasympathetic input results in a fixed, dilated pupil e.g. complete third nerve palsy
28
How would sympathetic effect pupillary response?
pupillary dilatation damage anywhere within the sympathetic pathway can lead to a constricted pupil
29
What are causes of dilated pupils?
Youth Dim lighting Anxiety, excitement “Mydriatic” eye drops Amphetamine, cocaine overdose Third nerve palsy Brain death
30
What are the causes of small pupils?
Old age Bright light “Miotic” eye drops Opiate overdose Horner’s Syndrome - rare disorder characterized by a constricted pupil (miosis), drooping of the upper eyelid (ptosis), absence of sweating of the face (anhidrosis), and sinking of the eyeball into the bony cavity that protects the eye (enophthalmos)
31
What are some eye movement disorders?
Isolated third nerve palsy Isolated fourth nerve palsy Isolated sixth nerve palsy Combination of the above Supranuclear gaze palsy Nystagmus
32
WHat are the causes of isolated third nerve palsy?
• Microvascular - diabetes, hypertension Painless, pupil spared • Compressive - posterior communicating artery aneurysm, raised ICP Painful, pupil affected
33
What are the causes of isolated sixth nerve palsy?
Numerous causes including: * idiopathic * diabetes * meningitis * raised intracranial pressure
34
What is nystahmus?
Congenital Serious visual impairment Peripheral vestibular problem Central vestibular/brainstem disease Cerebellar disease Toxins (medication and alcohol)
35
What is Trigeminal Neuralgia?
Paroxysmal attacks of lancinating pain a chronic pain condition that affects the trigeminal nerve, which carries sensation from your face to your brain
36
What causes Trigeminal Neuralgia?
Triggers Middle age and older Caused by vascular loop - Compression fifth nerve in the posterior fossa
37
What is the treatment of Trigeminal Neuralgia?
Treated medically with carbamazepine Surgical options if medication resistant
38
What is bells palsy, cause, symptoms and treatment?
Idiopathic facial nerve palsy Unilateral facial weakness Lower motor neurone type Often preceded by pain behind ear Eye closure affected Risk of corneal damage Treated with steroids Usually good recovery
39
What are examples of UMN and LMN disease?
UMN - stroke or tumour LMN - Bell’s Palsy, Lyme, sarcoid
40
What is Vestibular Neuronitis?
Sudden onset Disabling vertigo Vomiting Gradual recovery Cause uncertain ? viral
41
What is dysarthria ?
disordered articulation, slurring of speech
42
What is dysphagia?
difficulty swallowing
43
Both dysarthia and dysphagia occur in bulbar and pseudobulbar palsy, are they UMN or LMN?
Bulbar – lower motor neurone Pseudobulbar palsy – upper motor neurone
44
What is Pseudobulbar Palsy and what does it cause?
Bilateral UMN lesions e.g. in vascular lesions of both internal capsules, MND - dysarthria - dysphonia - difficulty in speaking due to a physical disorder of the mouth, tongue, throat, or vocal cords. refers to sound production - dysphagia - spastic, immobile tongue - brisk jaw jerk - brisk gag reflex
45
WHat is bulbar palsy and what does it cause?
Bilateral LMN lesions affecting IX - XII, eg. MND, polio, tumours, vascular lesions of the medulla and syphilis - wasted, fasciculating tongue - dysarthria - dysphonia - dysphagia BEWARE OF FEEDING THESE PATIENTS