Disorders of Esophagus Flashcards
Dysphagia
difficulty swallowing
most common symptom
Odynophagia
painful swallowing
Common Problem and Malfunction
Achalasia
absent or ineffective peristalsis of the distal esophagus
lower 2/3 of esophagus
- most often in 40 year olds
- incomplete relaxation of LES
Achalasia
Signs & Symptoms
- Dysphagia
- Sensation of food sticking in LES
- Noncardiac chest/epigastric pain or heartburn
- Secondary Pulmonary Complications
Achalasia
Assessment
- X-ray studies
- Barium swallow
- CT scan of chest and endoscopy
- Manometry
Manometry = confirmatory diagnostic examination
Achalasia
Management
- Small frequent feedings
- Ca channel blockers and nitrates
- Pneumatic dilation
- Esophagomyotomy
- Endoscopic myotomy
Achalasia (Management)
Ca channel blockers and nitrates
- ↓ esophageal pressure
- improve swallowing
- smooth muscle relaxants
Achalasia (Management)
Pneumatic dilation
stretch narrowed area
Achalasia (Management)
Esophagomyotomy
relax gastroesophageal junction
Achalasia (Management)
Endoscopic myotomy
pre-oral endoscopic myotomy (POEM)
Esophageal Spasm
abnormal muscle contractions in the esophagus
Esophageal Spasm
Types
- Diffuse Esophageal Spasm
- Hypertensive Peristalsis (Nutcracker Esophagus)
according to the book:
* DES
* Jackhammer esophagus
* Type III (spastic) achalasia
Type of Esophageal Spasm
Diffuse Esophageal Spasm
- uncoordinated spasms
- normal amplitude
- moves quickly and upwards
- only a portion is affected
regurgitate
Type of Esophageal Spasm
Jackhammer Esophagus (Hypercontractile Esophagus)
under Hypertensive Peristalsis
- extreme form
- coordinated movement
- entire is affected
Esophageal Spasm
Signs & Symptoms
- dysphagia
- odynophagia
- chest pain
Esophageal Spasm
Assessment
Esophageal Manometry
- measures motility and internal pressure
- LES
- standard test
- in side-lying position
Esophageal Spasm
Management
- Ca channel blockers
- nitrates
- smooth muscle relaxnts
- anti-cholinergics
- anti-anxiety
- PPIs
- soft diet
- Heller myotomy/POEM
Esophageal Spasm
Management
- Ca channel blockers
- nitrates
- smooth muscle relaxnts
- anti-cholinergics
- anti-anxiety
- PPIs
- soft diet
- Heller myotomy/POEM
Esophageal Spasm (Management)
Ca channel blockers
- first line of therapy
- nifedipine, verapamil
Esophageal Spasm (Management)
Ca channel blockers
- first line of therapy
- nifedipine, verapamil
Esophageal Spasm (Management)
Smooth Muscle Relaxants
- sildenafil/viagra
- after relaxing effect
Esophageal Spasm (Management)
Anticholinergics
Botulinum toxin
Esophageal Spasm (Management)
Anti-anxiety
tricyclic antidepressants
Esophageal Spasm (Management)
PPIs
omeprazole