Disorders of the anus and rectum Flashcards

1
Q

Internal vs. external hemorrhoids

A

○ Internal: Originate inside the rectum
■ Above the dentate (pectinate) line
○ External: Originate outside the anus

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2
Q

Prolapsed vs. Thrombosed hemorrhoids

A

● Prolapsed Hemorrhoids: When internal
hemorrhoidal tissue bulges outside the anal
opening
● Thrombosed Hemorrhoids: when a blood clot forms inside a hemorrhoidal
vein, obstructing blood flow and causing a painful swelling of the anal
tissues.

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3
Q

T/F Hemorrhoidal tissue is pathologic

A

F - it is not pathologic itself

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4
Q

_____ increases anorectal venous pressure, causing abnormal
dilatation and engorgement of the anal cushions

A

Intra-abdominal pressure

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5
Q

Can improving risk factors for hemorrhoids improve the hemorrhoids themself?

A

Yes

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6
Q

Etiology/Risk Factors of Hemorrhoids

A

● Advancing Age
● Prolonged sitting
● Physical inactivity/Obesity
● Chronic Diarrhea
● Chronic Constipation
● Straining or lingering seated while stooling
● Elevated resting anal pressure (increased sphincter tone)
● Things that make you strain (heavy lifting, chronic cough…)
● Portal Hypertension
● Tumors
Pregnancy:
● Present in 25 to 35% of pregnancies

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7
Q

Symptoms of Internal hemorrhoids

A

● Don’t cause cutaneous pain
○ Not innervated by cutaneous nerves
● They can rupture and bleed
● Perianal itching/irritation
● Pain can be caused by:
○ Sphincter spasm
○ Irritation to sensitive perianal skin

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8
Q

Symptoms of External hemorrhoids

A

● Bleeding
● Irritation (itching/burning)
● Not usually painful unless there is a thrombus
● Hygiene difficulties

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9
Q

Presentation of hemorrhoids

A

● Often asymptomatic
● Rectal bleeding
● Discomfort or pain - Usually aching or throbbing
○ Usually associated with thrombosis
● Irritation or itching of perianal skin
● Sensation of a bulge (Prolapsed internal hemorrhoids)

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10
Q

Symptoms - Acute Thrombosis of a hemorrhoid

A

● More common with external hemorrhoids
● Presents with acute onset of perianal pain with central swelling, usually a bluish perianal nodule present
● Can cause excruciating pain due to distention and inflammation of overlying perianal skin, which is highly innervated

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11
Q

Physical Exam for hemorrhoids

A

● A general abdominal exam to rule out
other diagnosis
● Visual inspection of rectum
● Digital rectal exam (not always
required for diagnosis)
● Anoscopy (if available)
● Note the size and location of findings (skin tags, thromboses)
● Assess the anal wink reflex

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12
Q

Diagnostic Testing for hemorrhoids

A

Diagnosis is almost always based on the clinic picture
● Lab tests not usually needed
● Anoscopy and/or flexible sigmoidoscopy are recommended to evaluate bright red rectal bleeding if cause is not easily determined.
● Colonoscopy should be considered if rectal bleeding is present with a negative anorectal exam

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13
Q

Treatment for hemorrhoids

A

● The best treatment is preventive
● Treat Constipation: Increase Fiber and Water intake
● Weight loss and increased physical activity
● Toilet retraining
● Decrease time on toilet

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14
Q

Treatment for hemorrhoids if symptomatic

A

● Warm baths 2-3 times daily, +/- epsom salt
● Stool softeners
● Topical analgesics
● Systemic analgesics
● Topical steroid cream

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15
Q

Medications for hemorrhoids

A

● Lidocaine ointment 5% (RectiCare)
● Witch hazel
● Preparation H

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15
Q

Nonsurgical Procedures for hemorrhoids

A

● Rubber Band Ligation
● Coagulation
● Electrocautery
● Electrotherapy
● Sclerotherapy
● Cryotherapy
● Laser therapy
● Radiowave ablation

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16
Q

Rubber band ligation

A

● For Grade 2 and 3 Internal hemorrhoids. Does not treat grade 4
● Effective in 75% of patients short-term
● A band ligature is passed through an anoscope and placed on the rectal mucosa
● Tissue will necrose and sloughs off in 1-2 weeks
● No to little anesthesia required

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16
Q

What is this procedure called?

A

Rubber band ligation

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17
Q

Management of Thrombosis in hemorrhoids

A

● Acutely thrombosed external hemorrhoids may be
excised if patient presents within 48-72 hours of
symptoms onset (not that helpful after that)
● Local anesthetic with epinephrine
● Elliptical incision
● Excision of thrombosis in the hemorrhoid
● Pressure dressing for several hours
● Let wound heal by secondary intention

18
Q

Hemorrhoidectomy

A

● For severely swollen and prolapsed
hemorrhoids
● Grades 3 and 4
● Operative hemorrhoidectomy is safe in
pregnancy, but avoid if possible
● Refer to GI
● Roughly 5% recurrence rate

19
Q

Anal Fissures

A

● PAINFUL linear tear or crack
● Distal anal canal
● Common cause of rectal bleeding in infants
● Can be an indication of abuse in children

20
Q

Pathophysiology of anal fissures

A

○ Majority=Trauma. Can be caused by:
■ Constipation and passage of a hard/painful bowel movements
■ Anal Sex
■ Diarrhea
■ Vaginal delivery
○ Others: Low-fiber diet, Prior anal surgery,
Abnormality of anal sphincter, Hypertonicity,
Elevated resting pressure of internal anal
sphincter

21
Q

Disease Progression for anal fissures

A

● Pain with bowel movements
● Raw area, becomes stretched
● Injured mucosa is abraded by the stool and wiping
● Internal sphincter begins to spasm

22
Q

Acute vs. Chronic anal fissures

A

● Acute if present for less than 6 weeks
○ Superficial
○ Linear tear in mucosa
● Chronic if present for greater than 6 weeks
○ Deeper
○ Hypertrophied anal papillae present proximally
○ Fibers of the internal anal sphincter visible
○ Commonly, Skin tags present distally

23
Presentation for anal fissures
● Severe pain with bowel movements ○ Minutes to hours ● Usually occurs with every bowel movement ● Patient begins to avoid bowel movements out of fear/apprehension. Worse with Constipation and Harder stools ● 70-75% of patients note bright red blood, especially with wiping
24
Labs for anal fissures
● Not indicated for an ordinary fissure, if Anterior midline or posterior midline ● If irregular, not midline, or if underlying pathology suspected ○ ESR ○ Culture ○ STD testing (including HIV) ○ Biopsy
25
visual examination for Anal fissures
○ Acute fissures appear as fresh, superficial lacerations, almost like a paper cut. ○ Chronic fissures have raised edges exposing the white, horizontally oriented fibers of the internal anal sphincter muscle fibers
26
Diagnostic imaging for anal fissures
Just visual exam needed ususally ● Digital rectal exam - Avoid ○ WILL BE PAINFUL - May worsen inflammation ● Anoscopy/rigid proctosigmoidoscopy ○ WILL BE PAINFUL ○ Only perform once symptoms have improved ● Chronic fissures are less painful, exam techniques are better tolerated and can be included
27
Initial Treatment of Anal fissures
○ Fiber supplementation ○ Stool softeners (like Docusate) ○ Laxatives as needed (like Senna) ○ Mineral oil ● Lidocaine-hydrocortisone rectal for pain ● Sitz baths - Provides good relief, helps heal Next step? ● Intra-anal nitroglycerin 0.4%
28
More Invasive Treatments for anal fissures
Botox (Botulinum toxin) ● Acute or chronic fissures ● Injected directly into the internal anal sphincter ● Effect lasts for 3 months Subcutaneous fissurectomy ● Cuts out the fissure without affecting the sphincters ● Less chance of incontinence than sphincterotomy
29
Surgical Treatment of anal fissures
● Lateral internal anal sphincterotomy
30
Lateral internal anal sphincterotomy
SOC for Anal fissures ○ Avoid on those with high risk of incontinence (like multiparous women or older patients) ○ Surgical procedure of choice ○ General or local anesthesia ○ Only the internal sphincter is cut ○ Continence disturbance rate at 2 years, about 14 percent (flatus incontinence 9 %, soilage/seepage 6 %, accidental defecation 1 %, solid stool incontinence 0.83 %)
31
Anorectal Abscess and Fistula
● Arise from infection of the epithelium lining of the anal canal ● Severity and depth of abscesses vary ● Abscess cavity often associated with the development of a fistula
32
Anal Fistula classifiecations
○ Intersphincteric (70%) - Found between the internal and external sphincters ○ Transsphincteric (23%) - Extends through the external sphincter into the ischiorectal fossa ○ Extrasphincteric (5%) - Passes from the rectum to the skin through the levator ani ○ Suprasphincteric (2%) - Extends from the intersphincteric plane through the puborectalis, exiting the skin after traversing the levator ani
33
Pathophysiology/Etiology of abscesses
● Anaerobes ○ Bacteroides fragilis, Peptostreptococcus, Prevotella, Fusobacterium, Porphyromonas, Clostridium ● Aerobes ○ Staphylococcus aureus, Streptococcus, Escherichia coli, MRSA ● 10% of anorectal abscesses form for reasons other than bacterial infection ○ Crohn’s, HIV, tuberculosis, cancer, STD, IBD, diverticular disease, foreign body, appendicitis
34
Presentation - Abscess
● Perianal pain, varies with abscess location ● Swelling around the rectum ● Perirectal drainage that is bloody, purulent, or mucoid ● Constipation ● Diarrhea
35
Presentation - Fistulas
○ Recurrent, malodorous perianal drainage ○ Pruritis ○ Perianal pain (if occluded) ○ Recurrent abscess ○ Pain occurs with sitting, moving, defecating, and coughing and is throbbing in nature ○ Patient may feel indent
36
What will you find on Digital Rectal Exam for an abscess?
A fluctuant, indurated mass
37
What will you find on Digital Rectal Exam for a fistula?
○ A fibrous tract or cord beneath the skin ○ Pus or blood may be expressible
38
Labs for abscesses
● Immunocompromised patients are at an increased risk of sepsis as a results of anorectal abscess ○ CBC with diff ○ ESR ● Cultures - VERY IMPORTANT ○ All I&D patients
39
Imaging for fistulas and abscesses
● Usually not necessary in the evaluation of simple perianal abscesses and fistulas ● Clinical suspicion of an intersphincteric or supralevator abscess may require confirmation ○ CT is readily available in most ERs and is commonly used ○ MRI is the best (if available) for imaging of anorectal abscesses (91% sensitivity)
40
Fistulography is used for what cases?
● To evaluate anal fistulas ○ Injection of contrast into the internal opening, radiographs performed ○ Can be painful when injecting the contrast material into fistulous ○ Generally reserved for cases in which there is a concern about a fistulous connection between the rectum and adjacent organs such as the bladder
41
Endosonography (perianal sonography) use for imaging
● Emerging as an excellent way of evaluating complex cases of perianal abscess and fistula ● Extent and configuration of the abscess and fistulas can be clearly visualized ● Becoming a test of choice where available
42
T/F it is okay to watch and wait anorectal abscesses
F - ○ Urgent incision and drainage with culture collection ○ No “watchful waiting” while administering antibiotics. It is inadequate ○ Delaying surgical intervention results in chronic tissue destruction, fibrosis, and stricture formation and may impair anal continence
43
Treatment of abscesses
○ Routine antibiotic treatment (in addition to drainage) ○ Bactrim DS or vancomycin ● Acute abscesses recur in roughly 10% of patients ○ Patients should be advised to return to the clinic or ER if symptoms of an abscess recur
44
Treatment of anal fistulas
○ Treat intra-abdominal disease ■ Crohn’s ○ Surgical intervention indicated for symptomatic patients ■ Fistulotomy vs. fistulectomy ■ Marsupialization ■ Anal flaps ○ Alternatively, a draining seton may be used to keep the fistula tract open, which often prevents recurrent abscess.