Disorders of the Endocrine System Flashcards

1
Q

What is the endocrine system?

A

interacts closely with nerves system and immune system to regulate all body functions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What does the endocrine system regulate?

A

all body processes including HR, BP, and elasticity of blood vessels.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What else does the endocrine system control?

A

-metabolism of water and nutrients
-controls physical growth and sexual development
-influence emotions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the endocrine glands?

A

-pituitary
-thyroid
-parathyroids
-adrenals: medulla and cortex
-pancreas
-ovaries
-testes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the characteristics of endocrine glands?

A

-ductless glands: release hormones directly into blood not through ducts
-glands are highly vascular

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What do hormones do in endocrine organs?

A

production and secretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is target tissue?

A

-when some hormones effect a specific site
-when other hormones effect multiple sites

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Why are hormones produced in endocrine glands?

A

to help regulate cellular and/ or chemical reactions that involve all bodily functions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are hormones released by?

A

signals from the nervous system, in response to hormone level changes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How do hormones know where to go?

A

it has its own receptor and will communicate only with specific target cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What do hormone disorders involve?

A

either hypo secretion or hyper secretion of a hormone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Why do nurses require general knowledge of hormones?

A

we administer drugs to replace or inhibit hormones and provide client education

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Hormones are produced and/ or released by endocrine organs in response to what?

A

a signal from the nervous system when a hormone level in the blood is too HIGH or too low

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

How does an endocrine hormone released?

A

-it is releases from the organ directly in the blood, not through a duct
-travels in blood and may not reach all cells although most have designated target cells, organ, or tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How can hormones be produced by neoplasms (tumors)?

A

-specific lung tumor produces ADH
-thyroid tumor produces thyroid hormone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Hyperfunction- Endocrine Problems

A

-excess hormone produced

-excessive gland stimulation and enlargement from autoimmune disorder

-gland tumor that produces hormone

-tumor outside a gland that produces hormones

-idiopathic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Hypofunction- Endocrine Problems

A

-congenital absence or defect of gland or enzyme needed for gland to produce hormone

-gland damage or destroyed by ischemia, infarctions, infection, inflammation or tumor

-gland atrophy that doesn’t produce hormone

-autoimmune disorder

-surgical removal

-hormone receptor deficits

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What are the functions of the hypothalamus?

A

-connects between endocrine and nervous system
-controls secretion of posterior pituitary hormones
-secrete releasing and inhibitory factor hormone that regulate anterior pituitary activities

19
Q

Why does the anterior pituitary act on target tissues or organs?

A

to stimulate the production of other hormones

20
Q

What is the role of the hypothalamus?

A

-maintains homeostasis

-regulates temperature, heart rate, blood pressure

-governs emotional behaviors

-secretes hormones that act on pituitary gland

21
Q

What does Syndrome of Inappropriate ADH look like?

A

-ADH EXCESS

-kidney tubules absorb more water resulting in fluid volume excess

-decreased serum osmolality

-concentrated urine

-hyponatremia

-hypertension

-weight gain

22
Q

What does Diabetes Insipidus (DI) look like?

A

-ADH deficiency

-kidney doesn’t reabsorb usual water resulting in fluid volume deficit

-increased serum osmolality

-large volume urine output

-hypernatremia

-hypotension

-weight loss

-possible shock due to decreased circulating volume

23
Q

What are the functions of the thyroid glands?

A

-regulates all aspects of metabolism

-nutrient metabolism

-temp

-growth and maturation

-blood vessel elasticity

24
Q

What is the role of thyroid stimulating hormone?

A

-stimulates the thyroid gland to secrete Thyroxine (T4) and Triiodothyronine (T3) into the blood for transport to target tissues

25
What micronutrient is essential for adequate thyroid function?
Iodine
26
What are sources of iodine?
salt and seafood
27
Hypothyroidism Clinical Manifestations
-low T3 and T4/ high TSH -inadequate thyroid functions hypometabolism -decreased appetite, weight gain -cold intolerance -fatigue -depression -reduced/ absent sweating -constipation -menstrual irregularity
28
What is myxedema?
-SEVERE life threatening hypothyroidism -widespread edema -enlarged tongue -hearing loss due to buildup of fluid in ear cavity
29
Hyperthyroidism- Clinical Manifestations
-high T3 and T4/ Low TSH -excess thyroid hormone -goiter if iodine deficiency -hypermetabolism -increased appetite, weight loss -heat intolerance -nervousness/ agitation -insomnia -expothalmos -menstrual irregularity
30
Thyrotoxic Crisis- Thyroid storm
-severe, life threatening hyperthyroidism -severe tachycardia -heart failure -severe hyperthermia -abdominal pain -delirium -coma -death
31
Where are the adrenal glands located?
atop each kidney
32
What is found in the outer part of the adrenals?
-glucocorticoids (raise BP) -aldosterone -testosterone
33
What do glucocorticoids control?
-carb, protein metabolism -emotional control -immune/ inflammatory response
34
What does the medulla (inner part) of the adrenals do?
Secretes epinephrine and norepinephrine
35
Hypercortisolism Etiology
-Cushing disease: excess adrenocorticotropic hormone (ACTH) from pituitary -adrenal tumor -non pituitary tumor that is secreting ACTH -Cushing syndrome: glucocorticoid drug therapy
36
Adrenal Cortical Insufficiency Etiology
-most common: rapid discontinuance of glucocorticoid drug therapy -primary: Addison disease: adrenal gland destruction
37
Hypercortisolism- Clinical Manifestations
-easy bruising -osteoporosis -hypokalemia -hyperglycemia -hypernatremia -hirsutism: excess hair -fat redistribution
38
Adrenal Cortical Insufficiency- Clinical Manifestations
-hypoglycemia -hyponatremia -hyperkalemia -hypotension -blotches of dark skin pigment -masculinization
39
What is the pancreas considered to be?
Both an exocrine and endocrine gland
40
What is the endocrine function of the pancreas?
secretes hormones that regulate glucose metabolism
41
What do beta cells release?
insulin
42
What do alpha cells release?
glucagon
43
What are the sources of glucose?
-food absorbed in small bowel -glucose administered IV -glucose converted from stored glycogen -metabolism of carbs, fat, protein
44