Disturbances of Consciousness Flashcards

(36 cards)

1
Q

Define consciousness

A

is the state of being aware of self and the environment

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2
Q

Describe an “alert” patient

A

full wakefulness and immediate and appropriate responsiveness

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3
Q

Describe a “confused” patient

A

inability to think with the usual speed and clarity

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4
Q

What is obtundation?

A

the patient is drowsy and indifferent to the environment, but responsive to verbal stimuli

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5
Q

What is stupor?

A

the patient is unconscious but rousable when stimulated

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6
Q

When would a patient be described as being in a coma?

A

the patient is unaware of self and the environment and is not rousable

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7
Q

What is important for forming a Dx relating to impaired consciousness?

A

the duration of impaired consciousness

- can be transient or ongoing

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8
Q

What does the normal conscious state depend on?

A

the integrity of the brainstem reticular activating system and the cerebral hemispheres

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9
Q

What are the most common causes of transient loss of consciousness (LOC) ?

A
  • Syncope
  • Seizures
  • Psychogenic/’non-epileptic’ attacks
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10
Q

What are uncommon causes of transient LOC?

A
  • Hypoglycaemia
  • Narcolepsy/cataplexy
  • Hyperventilation
  • Vertebrobasilar ischaemia
  • Vertebrobasilar migraine
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11
Q

What is syncope?

A

transient LOC and posture that results from a global reduction in blood flow to the brain

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12
Q

What are the main symptoms of syncope?

A
  • usually when standing
  • hypotensive symptoms: light-headed, faint, blurred/dim vision, sounds seem distant, nausea, hot/cold, sweating
  • pale skin colour
  • shallow respiration
  • floppy tone
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13
Q

What are the features of recovery from syncope?

A
  • Recovery is usually rapid with no confusion
  • Pallor may persist
  • No focal neurological signs
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14
Q

What are the 5 main causes of syncope?

A
  • Vasovagal syncope
  • Situational syncope; micturition/cough
  • Postural hypotension
  • Primary cardiac dysfunction
  • Carotid Sinus disease
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15
Q

What causes vasovagal syncope?

A

caused by a sudden drop in BP due to peripheral vasodilation (systolic drops to <60mmHg)

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16
Q

Describe micturition syncope

A

Men who get up to urinate in the middle of the night. it is a combination of vasodilation (from emptying of the bladder), postural hypotension (from standing) and bradycardia

17
Q

Describe cough syncope?

A

sustained coughing can increase intrathroacic pressure, which impairs venous return to the heart (valsalva). Increase in CSF pressure, reduction in pCO2 and resultant vasoconstriction may be contributory

18
Q

What is postural hypotension

A

upright posture is accompanied by an uncompensated fall in BP

19
Q

Who is postural hypotension likely to occur in?

A
  • Normal individuals
  • Drugs (antihypertensives)
  • Autonomic neuropathy (diabetes, Guillian-Barre)
  • Hypovolemia (blood loss, sepsis, hypoadrenalism)
  • Neurodegenerative disease (Parkinsons, mutlisystem atrophy)
20
Q

What conditions are likely to cause primary cardiac dysfunction syncope?

A
  • arrhythmias
  • LV outflow obstruction (aortic stenosis, hypertrophic obstructive cardiomyopathy)
  • RV outflow obstruction (pulmonary stenosis, pulmonary hypertension, PE)
  • Ventricular failure (acute anterior MI, dilated cardiomyopathy)
21
Q

How does carotid sinus disease cause syncope?

A

Hypertensive - less stretch needed for reflex bradycardia/decreased BP

22
Q

What are the prodromal symptoms for syncope caused by hypoglycaemia?

A
  • feeling tremulous and sweaty
  • palpitations
  • confusion
23
Q

What are the main causes of syncope caused by hypoglycaemia?

A
  • over treatment of diabetes
  • liver failure
  • hypopituitarism
  • Addison’s disease
  • insulinsomas
24
Q

What is narcolepsy?

A

excessive sleepiness and sleep attacks at inappropriate times

25
what is catoplexy?
attacks of sudden relaxation of muscle tone; usually precipitated by emotion/laughing
26
What is hyperventilation?
over breathing | This results In decreased pCO2, cerebral vasoconstriction, metabolic alkalosis and decreased ionised Ca2+
27
What are the main features of hyperventilation?
- breathlessness and air hunger with rapid respiration - light-headed - perineal and digital parasethesia - carpopedal spasm - anxiety and fatigue
28
What is vertebrobasilar ischaemia and what are the main symptoms?
- brainstem = supplied by the vertebrobasilar system - vertigo, nausea and diplopia VERY RARE
29
When are non-epileptic attacks diagnosed as a reason for LOC?
diagnosis of exclusion | A specialist should be consulted before giving this diagnosis
30
How does syncope differ from seizures?
unrelated to posture
31
What are the symptoms the precede a focal seizure/aura?
- deja vu - epigastric rising sensation - anxiety and fear - focal sensory symptoms - focal twitching
32
What are the clinical signs of a seizure?
- Skin = blue/normal - respiration = stertorous (noisy) - tone = tonic-clonic - convulsions and urinary incontinence - tongue biting - occasional focal neurological symptoms
33
What is a coma?
state of impaired consciousness in which the patient is not rousable despite external stimuli
34
Define a minimally conscious state
reduced cerebral metabolism on fMRI | Increased medial parietal lobe and posterior cingulate activity compared with more severe comas
35
Define persistent vegetative state
have lost neurological cognitive function and awareness of the environment but retain non cognitive function and preserved sleep-wake cycle
36
Define a permanent vegetative state
remain in a vegetative state for more than 6 months if caused by a non-TBI or more than 12 months if caused by a TBI