Diuretics

Question 1

How do carbonic anhydrase inhibitors work? Name an example

Answer 1

They act on the proximal convoluted tubule and inhibit the reabsorption of bicarbonate –> alkaline diuresis.
Example is acetazolamide

Question 2

How do loop diuretics work? Name an example

Answer 2

Work on the ascending limb of the loop of Henle to inhibit reabsorption of sodium, chloride and potassium. Furosemide and bumetanide are examples

Question 3

How do thiazide diuretics work? Name an example

Answer 3

Work on the distal convoluted tubule to inhibit reabsorption of sodium and chloride. Example is Bendroflumethiazide

Question 4

How do aldosterone antagonists work? Name an example

Answer 4

Work on the collecting duct to inhibit reabsorption of sodium and inhibit secretion of potassium. Example is spironolactone