Diuretics Flashcards

1
Q

Drug that affect the Bladder?

A

Ketamine (Causes Cystitis)

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2
Q

Important Drugs within Dieuritics

A

Dapagliflozin
Mannitol
Furosemide
Bendroflumethazide
Spironolacton
Tamsulosin
Oxybutynin
Mirabegron

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3
Q

Mannitol

A

Given through IV

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4
Q

Mannitol

A
  • Dieuritics, usually inhibit Na reabsorption but mannitol stimulate Na secretion
  • Given through IV
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5
Q

Diuretics that’s most commonly used in the treatment of Chronic HF?

A

Furosemide

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6
Q

Which diuretics is commonly used in the treatment of HTN?

A

Bendroflumethazide

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7
Q

Which ion transporter is the target site for the action of the loop of diuretic, furosemide?

A

Na/K/2Cl Symporter

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8
Q

Where is the target site for furosemide in a cell of the thick ascending limb of the Loop of Henle?

A

Luminal Cell membrane

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9
Q

Which of the following diuretics might produce Hyperkalaemia as an adverse effect?

A

Spironolactone

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10
Q

Reversible deafness can be an adverse effect of which diuretic ?

A

Furosemide

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11
Q

Which mechanism explains the ability of furosemide to enhance the tpoxicity of digoxin in HR?

A

induces hypokalaemia

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12
Q

How does the drug Dapagliflozin reduce blood sugar in the treatment of T2DM ?

A

Reduces the reabsorption of glucose by the kidney

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13
Q

Which cholinergic muscarinic antagonist is used to promote bladder relaxation in treating urinary incontinence?

A

Oxybutynin

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14
Q

Which adrenoreceptor agonist is used to treat urinary incontinence?

A

Mirabegron

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15
Q

Intravenous Fluid

A

Weight/Volume
1% Solution = 1g in 100mL
10% solution =10g in 100mL

ointment/gel would be weight
(estradiol gel 0.6%)

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16
Q

What is the percentage (W/V) in relation to drug solutions?

A

Weight of drug in grams in 100mL solvent

17
Q

How many grams of sodium chloride are in 1 litre bag of 0.9% saline?

A

9

18
Q

How many grams of glucose are in a 1 litre of bag of 5% glucose?

A

50 grams