Diuretics Flashcards

1
Q

what are Diuretics used for

A

Treat HTN and Mobilize edematous fluid to prevent renal fail, also high altitude sickness

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2
Q

3 functions of Diuretic

A

Maintain acid-base balance, Excrete metabolic waste and foriegn substance, Cleanse ECF and maintain ECF Vol.

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3
Q

how do diuretics work

A

prevent reabsorbtion of Na and Chloride

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4
Q

Acetazolaminde used to treat

A

Glaucoma, edema, high altitude sickness

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5
Q

Acetazolamide side effects that can be good

A

induce metabolic acidosis=seizure prevention also induces respiratory acidosis=increased O2 during hypoxia

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6
Q

Acetazolamide: side effects

A

elevate blood glucose, drowsy, anorexia, photosensitivity, itching, melena, hematuria

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7
Q

Acetazolamide more or less potent than loop and thiazide diuretic?

A

Less

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8
Q

Acetazolamide can cause an decrease in what?

A

Potassium

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9
Q

Acetazolamide toxic with what drug

A

digitalis

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10
Q

name 2 loop diuretics

A

Furosemide and Bumetanide

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11
Q

5 Major effects of Loop Diuretic

A

lower BP, Reduce Pulmonary vascular resistance, reduce central venous pressure, reduce left ventricular end-diastolic pressure

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12
Q

Loop Diurets cause a major loss of

A

electrolytes (Na & K+) also some CA+ and Chloride

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13
Q

Loop Diuretics treat :

A

Pulmonary edema, also edema assoc. w/ liver and renal disease. control HTN, inc. secretion of Ca

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14
Q

Loop Diuretics Adverse effects:

A

HoNatremia, HoChloremia, Dehydration, excessive weight loss

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15
Q

Can Loop Diuretics be used with low GFR?

A

Yes

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16
Q

what are the effects of Dehydration w/ loop diuretics

A

thrombosis, embolism: symptoms=pain in chest, calves, or pelvis

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17
Q

Furosemide is reserved for:

A

rapid or massive mobilization of fluid. pulmonary edema and ascites

18
Q

Furosemide adverse effects

A

Ototoxicity, HoKalemia, Electrolyte loss

19
Q

With Loop Diurectics watch out for what allergy

20
Q

Nursing Implications for Diuretics: monitor for

A

Monitor I&O, K+, weight, vitals, hearing loss (1-24hr)

21
Q

Nursing Implications for Diuretics: teach

A

medicate early in day=decrease nocturia, report hearing loss or signs of gout

22
Q

Osmotic diuretic

23
Q

Mannitol produces

A

rapid diureses

24
Q

How does Mannitol work on kidney

A

induce vasodilation which increase GFR and renal plasma flow=preven kidney damage

25
Mannitol treats
intracranial and intraocular pressure
26
What happens to manitol at low levels
crystalize
27
how to administer Mannitol
Parenterally through IV fliter
28
SE of Mannitol
Convulsions, thrombophlebitis, & pulmonary congestion
29
Sprinalactone and triamterene are what type of Diuretic
Potassuim- Sparing
30
Sprinalactone and Triamteren are given for
Edema, HTN, HF, ascites
31
Sprinalctone: the ugly
Gynecomastia, amenorrhea, hyperkalemia
32
Triamterene adverse effects
reduce folic acid and cause kidney stone, leg cramps
33
Interactions with potassium sparing diuretic
Ace-inhibitor, K+ supplement=hyperkalemia. lithium=lithium toxicity NSAIDS=decreases blood flow to kidney=diminished response
34
spironolactone monitor for
I&O, K+ and Na+, cardiac dysrhythmias
35
Spironolactone Teach pt.
restrict K+ food, take meds w/or after meal for GI upset, notify DR. of menstral irregularities and gynecomastia and impotence
36
Hydrochlorothiazide-what do they do?
Increase output of Na+, K+, H2O Also elevate glucose and uric acid
37
Are Thiazides More or less effective than loop diuretic
less
38
Thiazides are used w/ what drug to conteract adverse metabolic effects
Potassium sparing Diuretic
39
Thiazide AE:
HoNatremia, HoChloremia, HoKalemia, Dehydration
40
Thiazide drug interaction
Digoxin=slow HR&increase Hrt squeeze also HoKalemia, NSAIDS=decreased diuretic activity, Lithium =accumulation of lithium
41
Thiazide identify high risk pt.
Digoxin, Lithium, ant-HTN drugs, CVD, renal impairment, Diabetes, Hx of gout