DM

Question 1

sitagliptin phosphate

Answer 1

Januvia

DPP4 Inhibitor (stop met of GLP-1)

Question 2

saxagliptin

Answer 2

Onglyza

DPP4 Inhibitor (Stop met of GLP-1)

Question 3

linagliptin

Answer 3

Tradjenta

DPP4 Inhibitor (stop met of GLP-1)

Question 4

alogliptin

Answer 4

Nesina

DPP4 Inhibitor (stop met of GLP-1)

Question 5

exenatide

Answer 5

Byetta or Bydureon (ER)

GLP-1 AGonist
Weight loss

Question 6

liraglutide

Answer 6

Victoza

GLP-1 AGonist
Weight loss

Question 7

dulaglutide

Answer 7

Trulicity

GLP-1 AGonist
Weight loss

Question 8

albiglutide

Answer 8

Tanzeum

GLP-1 AGonist
Weight loss

Question 9

lixisenatide

Answer 9

Adlyxin

GLP-1 AGonist
Weight loss

Question 10

canagliflozin

Answer 10

Invokana

SLGT2 Inhibitor (pee glu)

Question 11

dapagliflozin

Answer 11

Farxiga

SLGT2 Inhibitor (pee glu)

Question 12

empagliflozin

Answer 12

Jardiance

SLGT2 Inhibitor (pee out glu)

Question 13

bromocriptine

Answer 13

Cycloset

Dopamine AGonist

Question 14

DPP4 Inhibitors MOA

Answer 14

Stop metabolism of GLP-1

Weight neutral

Question 15

DPP4 Inhibitors Brands

Answer 15

Januvia - sitagliptin phosphate
Onglyza - saxagliptin
Nesina - alogliptin
Tradjenta - linagliptin

DPP4 Inhibitors (stop met of GLP-1)
Weight neutral

Question 16

GLP-1 AGonist Brands

Answer 16

ATT By Victoria (the tides = loss)
Byetta and Bydureon  - exenatide
Victoza        - liraglutide 
Trulicity       - dulaglutide 
Tanzeum     - albiglutide
Adlyxin        - lixisenatide

GLP-1 AGonist
Weight loss

Question 17

SLGT2 Inhibitors Brands

Answer 17

Invokana - canagliflozen
Farxiga - dapagliflozen
Jardiance - empagliflozen

Pee out glucose - FLOWzen

Question 18

glimepiride

Answer 18

Amaryl

Safe in renal failure (100% liver)
- reduce dose
Sulfonylurea
Secrete insulin

Question 19

glipizide

Answer 19

Glucotrol

DOC in RENAL FAILURE (no dose adj)
EMPTY STOMACH (30 min before meal)

Sulfonylurea
Secrete insulin

Question 20

glyburide

Answer 20

Micronase - DiaBeta
Micronized - Glynase

Sulfonylurea
Secrets insulin

Question 21

List Biguanides Brands

Answer 21

Metformin brands:
Glucophage - 2550/d
Glucophage XR - 2500/d
Fortamet ER - 2500/d - full glass water
Glumetza ER - 2000/d

QD with evening meal

Question 22

Biguanide Combos

Answer 22

Glucovance (glyburide/met)
Avandamet (rosiglitazone/M)
Jentaduo (linagliptin/M)
Actoplus Met (pioglitazone/M)
Prandimet (repaglinide/M)
Kombiglyze XR (saxagliptin/M)
Kazano (alogliptin/M)
Invokamet (canagliflozen/M)
Xigduo (dapagliflozen/M)
Synjardy (empagliglozen/M)

Question 23

Thiazolidinedione Brands

Answer 23

Avandia - rosiglitazone
Actos - pioglitazone

XXX CHF II/III
Work on receptors

Question 24

Alpha-Glucosidase Inhibitor Brands

Answer 24

Precose - acarbose
Glyset- miglitol

Bind sucrose
Lower post prandial hyperglycemia

Question 25

acarbose

Answer 25

Precose Alpha-glycosidase Inhibitor Bind sucrose Lower post prandial hyperglycemia

Question 26

miglitol

Answer 26

Glyset Alpha-Glucosidase Inhibitor Bind sucrose Lower post prandial hyperglycemia

Question 27

Meglitinides Brands

Answer 27

Prandin - repaglinide Starlix - nateglinide Secrete insulin (like sulfonylureas)

Question 28

repaglinide

Answer 28

Prandin ``` Meglitinide Secrete insulin (like sulfonylureas) ```

Question 29

nateglinide

Answer 29

Starlix ``` Meglitinide Secrete insulin (like sulfonylureas) ```

Question 30

Biguanide MOA

Answer 30

Metformin Decrease hepatic glucose production Stim glycolysis in liver Improves insulin sensitivity Does NOT cause hypoglycemia Does NOT cause weight gain (weight loss) Favorable lipid effects

Question 31

rosiglitazone

Answer 31

Avandia Thiazolidinedione XXX - CHF Work on receptors

Question 32

pioglitazone

Answer 32

Actos Thiazolidinedione XXX CHF Work on receptors

Question 33

GLP-1 Agonists MOA

Answer 33

Increase insulin production Stop liver from making too much glu Reduce appetite - weight loss

Question 34

Any med that increases insulin secretion can...?

Answer 34

Cause hypoglycemia Examples: Insulin Sulfonylurea Most except metformin