DM Drug BRAND/GENERIC and MoA Flashcards

(18 cards)

1
Q

Metformin

A

Glucophage or Glumeta (brand only)

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2
Q

pioglitazone

A

Actos

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3
Q

sitagliptin

A

Januvia

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4
Q

saxagliptin

A

Onglyza

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5
Q

linagliptin

A

Trajenta

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6
Q

alogliptin

A

Nesina

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7
Q

canagliflozin

A

Invokana

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8
Q

dapagliflozin

A

Farxiga

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9
Q

empagliflozin

A

Jardiance

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10
Q

exenatide

A

Byetta (BID) or Bydureon (QW)

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11
Q

liraglutide

A

Victoza

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12
Q

albiglutide

A

Tanzneum

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13
Q

dulaglutide

A

Trulicity

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14
Q

glipizide

A

Glucotrol

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15
Q

glyburide

A

Micronase

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16
Q

glimepiride

17
Q

What is the MoA for SGLT2 inhibitors

A

decreased reabsorption of renally filtered glucose and lowers the renal threshold for glucose increasing the glucose excreted in the urine

18
Q

What is the MoA of DPP4 inhibitors?

A

DPP4 inactivate incretins that are secreted in the intestine in response to a meal (GLP-1 and GIP); GLP-1 and GIP act as messages to the pancreas to release more insulin and decrease glucagon