DM Pharm

Question 1

Metformin

Answer 1

Glucophage

- biguanides

Question 2

Glimepiride

Answer 2

• amaryl

Sulfonylurea

Question 3

Glipizide

Answer 3

Glucotrol

Sulfonylurea

Question 4

Glyburide

Answer 4

• diabeta; micronase

- sulfonylurea

Question 5

Exenatide

Answer 5

Byetta
QD SC IJ
Short acting
GLP-1 analogs

Question 6

Liraglutide

Answer 6

Victoza
QD SC IJ
Short acting
GLP-1 analogs

Question 7

Lixisenatide

Answer 7

Adlyxin
QD SC IJ
Short acting
GLP-1 analog

Question 8

Exenatide

Answer 8

Bydureon
Qweekly SC IJ
Long acting
GLP-1 analog

Question 9

Albiglutide

Answer 9

Tanzeum
Qweekly SC IJ
Long acting
GLP-1 analog

Question 10

Dulaglutide

Answer 10

Trulicity
Qweekly SC IJ
Long acting
GLP-1 analog

Question 11

Sitagliptin

Answer 11

DPP-4
Januvia
PO qd

Question 12

Saxegliptin

Answer 12

Onglyza
DPP-4 inhibitors
PO qd

Question 13

Linagliptin

Answer 13

Tradjenta
DPP-4 inhibitors
PO qd

Question 14

Alogliptin

Answer 14

Nesina
DPP-4 inhibitors
PO qd

Question 15

Canagliflozin

Answer 15

Invokana
SGLT2- inhibitors
PO and titration up

Question 16

Dapagliflozin

Answer 16

Farxiga
SGLT2- inhibitors
PO qd

Question 17

Empagliflozin

Answer 17

Jardiance
SGLT2- inhibitors
PO qd

Question 18

Pioglitazone

Answer 18

Actos
TZD
PO qd

Question 19

Rosiglitazone

Answer 19

Avandia
TZD
PO qd

Question 20

Acarbose

Answer 20

Precose
Alpha-glucosidase inhibitors
AC TID

Question 21

Miglitol

Answer 21

Glyset
Alpha-glucosidase inhibitors
AC TID

Question 22

Repaglinide

Answer 22

Prandin
Meglitinides
ACHS

Question 23

Nateglinide

Answer 23

Starlix
Meglitinides
ACHS

Question 24

Insulin lispro

Answer 24

Humalog 
Rapid acting insulin
Onset of action: 5-10 min
Duration: 45-75 min
Lasts: 2-4 hr

Question 25

Regular insulin

Answer 25

- regular 100 U/mL - short acting Onset of action: 30 min Duration: 2.5-5 hr Lasts: 4-12 hr

Question 26

Insulin aspart

Answer 26

``` Novolog Rapid acting insulin Onset of action: 5-10 min Duration: 45-75 min Lasts: 2-4 hr ```

Question 27

Insulin glulisine

Answer 27

``` Apidra Rapid acting insulin Onset of action: 5-10 min Duration: 45-75 min Lasts: 2-4 hr ```

Question 28

Insulin glargine

Answer 28

Lantus Long acting insulin - basal bolus in SQ QD dosing

Question 29

U-300 insulin glargine

Answer 29

Toujeo Long-ultralong acting insulin For dosages >300 units/mL—> pt receives like 200 units/mL

Question 30

Insulin detemir

Answer 30

Levemir Intermediate to long acting insulin Duration 17-23 hours; rq. 2-3 qd bolus IJ

Question 31

Insulin degludec

Answer 31

``` Tresiba Ultra long acting insulin Peaks in 9 hours 1/2life: 25 hr; duration: 42 hr Start @ 0.2-0.4 units/mL in T1DM Start @ 10 U qd in T2DM—> steady state 3-4 days ```

Question 32

Inhaled insulin

Answer 32

Afrezza Pts unwilling to use SC insulin Peaks in plasma in 15 minutes and peaks action occurs in less than an hour

Question 33

Mixtures of insulins:

Answer 33

70% NPL, 30% Insulin lispro (humulin 70/30) 70% NPH, 30% Insulin aspart (novulin 70/30) 70% insulin degludec, 30% insulin aspart (Ryzodeg 70/30)