DNA damage + repair Flashcards

1
Q

BER- cause, enzyme + base changes

A

ROS; glycolase; G to T

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

NER- causes, solution

A

xeroderma pigmentosum; base flip

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Example of chemical instability

A

depurination + deamination of cytosine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How TLS works:

A

has large active site and swaps with machinery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

MMR disease

A

colorectal carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Non-homologus- stage; disease

A

G1 ; leukemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Homologus- stage; needs

A

S-G2; RAD51

How well did you know this?
1
Not at all
2
3
4
5
Perfectly