dna history

Question 1

miescher

Answer 1

PUS CELLS
found NUCLEIN
(debate of proteins vs nuclein)

Question 2

hammerling

Answer 2

ACETABULARIA
caps regrew (according to foot), foot didnt

hereditary info = nucleus

Question 3

griffith

Answer 3

PNEUMONIA VACCINE
substance (transforming principle) could transfer virulence to non virulent bacteria

Question 4

hershey and chase

Answer 4

BACTERIOPHAGES with radioactive labels on DNA and proteins
DNA enter bacteria, not proteins (dna = transforming factor)

Question 5

LEVEN

Answer 5

Isolated 2 NUCLEIC ACIDS
found that each nucleotide = 1/4 N bases, sugar, phosphate group

BUT thought tetranucleotide

Question 6

chargaffs rule

Answer 6

AT, GC (% composition)

Question 7

pauling

Answer 7

many proteins have helix shapes

Question 8

franklin and maurice

Answer 8

x ray DIFFRACTION showed proteins structure (backbone and helix)

Question 9

x ray diffraction:

Answer 9

(franklin and maurice) x rays deflected by atoms in molecule = pattern of light and dark lines on film

Question 10

watson and crick

Answer 10

looked at C, F, W’s work, deduced LADDER HELIX (sugar phosphate sides, bases rungs