All DNA viruses are dsDNA except the Parvoviridae Memory aid: All DNA viruses are LID except All are dsDNA (like our cells), except “part-of-avirus” (parvovirus) is ssDNA Etymology: Parvo means small: small and single

All are linear except: papilloma- (circular, supercoiled) polyoma- (circular, supercoiled) hepadnaviruses (circular) Memory aid: All DNA viruses are LID except He’s not in line; so hep pop and pol

Herpesvirus Strand Envelope Symmetry Shape

Strand Double stranded Envelope Yes Symmetry Icosahedral Shape Liner Summary: All DNA viruses are LID except

1. Which herpesvirus most often causes oral lesions as well as keratoconjunctivitis? 2. Which herpesvirus most often causes genital lesions in humans?

1. Herpes simplex virus type 1 2. Herpes simplex virus type 2

Hepadnavirus Strand Envelope Symmetry Shape Example

Strand Partially ds Envelope Yes Symmetry Icosahedral Shape Circular Example Hepatitis B Memory aid: All DNA viruses are _LID_ except – _L_inear, _I_cosahedral, _D_ouble stranded All DNA viruses are linear except papillomavirus, polyomavirus, and hepadnavirus All DNA viruses icosahedral except poxvirus All DNA viruses are DS except parvovirus

DNA viruses overview Flashcards by Julius Riazonda

What are the DNA viruses?

Hepadnavirus
Herpesvirus
Adenovirus
Poxvirus
Parvovirus
Papillomavirus
Polyomavirus

Memory aid:

DNA viruses are _HHAPPPP_y viruses!
- Heppy (Hepadna)
- Herpes
- Adelle
- Fucks
- Pervy
- Pappi
- Polyo

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All DNA viruses are ____, ____ and ____ with some exceptions

Linear
Icosahedral
DsDNA

Memory aid:

All DNA viruses are LID except – Linear, Icosahedral, Double stranded
- All DNA viruses are linear except papillomavirus, polyomavirus, and hepadnavirus
- All DNA viruses icosahedral except poxvirus
- All DNA viruses are DS except parvovirus

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DNA strands

All DNA viruses are dsDNA except the Parvoviridae

Memory aid:

All DNA viruses are LID except
All are dsDNA (like our cells), except “part-of-avirus” (parvovirus) is ssDNA
Etymology:*
Parvo means small: small and single

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Genome shape

All are linear except:
- papilloma- (circular, supercoiled)
- polyoma- (circular, supercoiled)
- hepadnaviruses (circular)

Memory aid:

All DNA viruses are LID except
He’s not in line; so hep pop and pol

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Site of DNA virus replication

All DNA viruses replicate in the nucleus (except poxvirus – carries own DNA-dependent RNA polymerase and can replicate without nuclear enzymes)

Memory aid:

DNA
Dun sa Nucleus
Pox is out of the box (nucleus)

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DNA symmetry

Are icosahedral except pox which is complex

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Only DNA virus that produces DNA by reverse transcription

Hepadnavirus

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Which are enveloped DNA viruses?

All are naked except:
- Hepadnavirus
- Herpesviruses
- Poxvirus

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Herpesvirus

Strand
Envelope
Symmetry
Shape

Strand
- Double stranded
Envelope
- Yes
Symmetry
- Icosahedral
Shape
- Liner
Summary:*
All DNA viruses are LID except

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Examples of herpesvirus

Herpes simplex virus-1
Herpes simplex virus-2
Varicella-Zoster virus (HHV-3)
Epstein-Barrvirus (HHV-4)
Cytomegalovirus (HHV-5)
Human herpesviruses 6 and 7
Human herpesviruses 8

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Herpesvirus that is not medically significant

Human herpesvirus 7 is not clinically significant

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Which herpesvirus most often causes oral lesions as well as keratoconjunctivitis?
Which herpesvirus most often causes genital lesions in humans?

Herpes simplex virus type 1
Herpes simplex virus type 2

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All DNA viruses contain double-stranded DNA, except for which family?

Parvoviridae, which has single-stranded DNA

Remember:*
Part-of-a-virus

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Hepadnavirus

Strand
Envelope
Symmetry
Shape
Example

Strand
- Partially ds
Envelope
- Yes
Symmetry
- Icosahedral
Shape
- Circular
Example
- Hepatitis B

Memory aid:

All DNA viruses are LID except – _L_inear, _I_cosahedral, _D_ouble stranded
All DNA viruses are linear except papillomavirus, polyomavirus, and hepadnavirus
All DNA viruses icosahedral except poxvirus
All DNA viruses are DS except parvovirus

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Unique property of hepadnavirus

Not a retrovirus but has reverse transcriptase

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Spherical particle found in the serum in hepatitis B

Study These Flashcards

Dane particle

Poxvirus

Strand
Envelope
Symmetry
Shape

Study These Flashcards

Strand
- DS
Envelope
- Yes
Symmetry
- Complex
Shape
- Linear

Memory aid:

All DNA viruses are LID except – _L_inear, _I_cosahedral, _D_ouble stranded
All DNA viruses are linear except papillomavirus, polyomavirus, and hepadnavirus
All DNA viruses icosahedral except poxvirus
All DNA viruses are DS except parvovirus

Disease (s) caused by poxvirus

Study These Flashcards

Smallpox
Cowpox (“milkmaid blisters”)
Molluscum contagiosum

Adenovirus

Strand
Envelope
Symmetry
Shape

Study These Flashcards

Strand
- DS
Envelope
- No
Symmetry
- Icosahedral
Shape
- Linear

Memory aid:

All DNA viruses are LID except – _L_inear, _I_cosahedral, _D_ouble stranded
All DNA viruses are linear except papillomavirus, polyomavirus, and hepadnavirus
All DNA viruses icosahedral except poxvirus
All DNA viruses are DS except parvovirus

Diseases caused by adenovirus

Study These Flashcards

Conjunctivitis (“pink eye”)
- Most common cause is adenovirus
URT infections
- Coryza, febrile pharyngitis
GUT infection
- Acute hemorrhagic cystitis
LRT infection
- Bronchitis, atypical pneumonia
GIT infection
- Acute gastroenteritis

Memory aid:

Just imagine adelle cancelling her concert because of these!
- Hindi maka-kanta d/t sore throat
- Hindi maka-eye-to-eye d/t conjunctivitis
- Hindi makahinga d/t pneumonia
- Nag-iihi ng dugo
- Nagtatae

Histopath finding in adenovirus infection

Study These Flashcards

Cowdry type B intranuclear eosinophilic inclusions

Papillomavirus

Strand
Envelope
Symmetry
Shape

Study These Flashcards

Strand
- DS
Envelope
- No
Symmetry
- Icosahedral
Shape
- Circular

Mnemonic:

All DNA viruses are LID except
- Linear except hepadnavirus, papillomavirus and polyomavirus
- Icosahedral except poxvirus
- Double stranded except parvovirus

Parvovirus

Strand
Envelope
Structure
Shape
Example

Study These Flashcards

Strand
- SS
Envelope
- No
Structure
- Icosahedral
Shape
- Linear
Example
- B19

Mnemonic:

All DNA viruses are LID except
- Linear except hepadnavirus, papillomavirus and polyomavirus
- Icosahedral except poxvirus
- Double stranded except parvovirus

Diseases caused by parvovirus

Study These Flashcards

Pure RBC aplasia
Aplastic crises
Rheumatoid arthritis-like symptoms
V^th (5^th) disease
hydrOps fetalis (d/t RBC destruction)

What skin exanthem does parvovirus B19 cause in children?

Erythema infectiosum ("slapped-cheek" rash) * Memory aid:* * *slaPParvo*

Sequela of parvovirus fetal infections in relation to AOG

* 1^st trimester – fetal death * 2^nd trimester – hydrops fetalis

Chickenpox, zoster, and shingles are caused by what DNA virus?

Varicella zoster virus

All DNA viruses are icosahedral except which one?

Poxvirus; it is complex

Which types of patients are particularly vulnerable to significant cytomegalovirus infection?

Immunosuppressed patients (especially transplant recipients) and the fetuses of infected mothers

EBV * Another name * Strand * Envelope * Symmetry * Shape

* Another name * HHV 4 * Strand * Double stranded * Envelope * Yes * Symmetry * Icosahedral * Shape * Linear *Memory aid:* * *All DNA viruses are LID except* * *Hepadna, Papilloma and Polyoma which are not linear* * *Icosahedral except pox which is complex* * *Double stranded except parvovirus which is single stranded*

Epstein-Barr virus causes what conditions?

* Infectious mononucleosis * Burkitts lymphoma * Nasopharyngeal carcinoma

Disease caused by HHV 6 and 7

Roseola infantum (exanthem subitum) * Note:* * *HHV-7 is less common cause of roseola* * Memory aid:* * *HHV-_6_ | Ro-_6_-la | Exanthem _6_-bitum*

Which DNA virus is associated with Kaposi sarcoma?

Human herpesvirus type 8 (Kaposi’s sarcoma-associated herpesvirus)

Polyomavirus * Strand * Envelope * Symmetry * Shape * Examples

* Strand * DS * Envelope * No * Symmetry * Icosahedral * Shape * Circular * Examples * JC virus * BK virus * Memory aid:* * *All DNA viruses are LID except*

Example (s) of polyomavirus virus and disease (s) caused

* JC virus * Progressive multifocal leukoencephalopathy (PML) in HIV * BK virus * Transplant patients, commonly targets kidney *Memory aid:* * *JC: Junky Cerebrum* * *BK: Bad Kidney*

HSV-infected cells contain inclusion bodies known as what?

Cowdry A intranuclear inclusions

DNA viruses overview Flashcards

(36 cards)