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Junior - Pharm II - 3 > DOC > Flashcards

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1
Q

Syphilis (T. Pallidum)

A

Penicillin G Bicillin La

Natural penicillins - 1st gen

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2
Q

PCN sensitive gangrene (c. Perfringen)

A

Natural PCN - 1st gen

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3
Q

Animal bites

A

Amoxicillin/clavulanate (augmentin)

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4
Q

Human bites

A

Early: amoxicillin/clauvalante PO x 5 days

Later: Ampicillin/Sulbactam IV Q6H or Cefoxitin 2 grams IV q 8h.

PCN allergic​: Clindamycin + either Ciprofloxacin or TMP/SMX

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5
Q

n. Gonorrhea “coming out of their wherever”

A

Ceftriaxone (rocephin) IV

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6
Q

Meningitis

A

3rd gen cephalosporin

Ceftriaxone

Not for neonate: ca2+ crystals in lungs and biliary slugging

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7
Q

Pre/post surg not in abdomen

A

Cefazolin (ancef)

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8
Q

Mild or moderate C. Difficile

A

Metronidazole x 10-14 days

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9
Q

Severe C. Difficile

A

Vancomycin PO x 10-14 days

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10
Q

Mild to moderate CAP

A

Macrolides: clarith or azithro

Doxy

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11
Q

E. Coli, klebsiella, P. Areuginosa, acinobacter (gram -)

A

Aminoglycosides

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12
Q

Anthrax (inhalation, cutaneous and GI)

A

Ciprofloxacin

Or

Doxycycline

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13
Q

Impetigo

A

Mupirocin (bactroban)

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14
Q

Tularemia (francisella tularensis)

A

Streptomycin IV or gentamicin

Alt doxy/ciprofloxacin

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15
Q

Brucellosis

A

Doxycycline

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16
Q

Q-fever (coxiella burnetii)

A

Doxycycline

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17
Q

Uncomplicated cystitis

A 
TMP/SMX x 3 days
Or
Nitrofuratonin x 5 days 
Or
Fosfomycin x 1 dose
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18
Q

Uncomplicated pyelonephritis

A

TMP/SMX x 14 days
Or
Fluroquinolone x 5-7 days

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19
Q

Complicated UTI

A

Fluoroquinolone (2nd, 3rd, or 4th gen)

Aminoglycosides

Extended spectrum b-lactam

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20
Q

UTI in pregnancy

A 
7 days of: 
Amoxicillin
Or 
Nitrofurantoin 
Or
Cephalexin
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21
Q

Never use in pregnancy

A

Fluroquinolones
TMP/SMX
Aminoglycosides
Tetracyclines

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22
Q

CAP w no comorbitdities

A

Macrolides:

  • clarithromycin
  • azithromycin

Or doxycycline

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23
Q

CAP w comorbidities or abx in last 3 months

A

Resp fluoroquinolone

  • moxifloxacin
  • levofloxacin

Macrolide or doxy plus:

  • amoxicillin
  • amoxicillin/cauvulanate
  • ceftriaxone (IV/IM)
  • cefpodoxime
  • cefuroxime
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24
Q

Inpatient CAP

A

Anti-pneumococcal B-lactam + azithromycin

Anti-pneumococcal B-lactam + moxifloxacin or levofloxacin

PCN allergy: aztreonam + moxifloxicin or levofloxacin

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25
Pneumona w P. Aeruginosa
``` Antipseudomonal B-lactam + Ciprofloxacin or levofloxacin Or aminoglycoside + azithromycin Or Aminoglycoside + ciprofloxacin or levofloxacin ```
26
Hospital/ventilator acquired pneumonia
MRSA coverage: vancomycin or linezolid ``` P. aeruginosa: Antipseudomonal B-lactam + Ciprofloxacin or levofloxacin Or aminoglycoside + azithromycin Or Aminoglycoside + ciprofloxacin or levofloxacin ```
27
MRSA
- Trimethoprim/sulfamethoxazole (PO/IV) - Clindamycin (PO/IV) - Doxycycline (PO/IV) - Vancomycin, dalbavancin, oritavancin, or telavancin (IV) - ceftaroline (IV) - linezolid or tedizolid (PO/IV) - daptomycin(IV)
28
Relapse or resistant C. Difficile
Intracolonic vancomycin Fidaxomicin x 10 days Fecal microbiota transplant Subtotal colectomy
29
Anti-fungal
You made it 2 sections
30
Fungal pneumonia that doesnt respond to antifungals
Sulfamethozazole/trimethoprim (septra)
31
Vaginal candidiasis
Fluconazole
32
Candida prophylaxid in hematopoietic cell transplant recipients
Micafungin (mycamine)
33
Invasive candidiasis including candidemia
Caspofungin (cancidas)
34
Oral tx of onychomycosis
Terbinafine or itraconazole
35
Tinea versicolor
Ketaconazole 2% cream x 2 weeks
36
Fungal infections including invasive and noninvasive candidiasis and cryptococcal disease
Fluconazole (diflucan)
37
Prophylaxis against invasive fungal infections in AIDs
Fluconazole (diflucan)
38
Invasive pulmonary or extra pulmonary infections caused by candida spp
Voriconazole (Vfend)
39
Prophylaxis against asperigullosis and candida infections in AIDS
Posaconazole
40
Aspergillus infections
Voriconazole (Vfend)
41
Oncychomycosis
Terbinafine (lamisil) or itraconazole PO Toenails x 12 wk Fingernails x 6 wk
42
Serious invasive fungal infection
Amphotericin B
43
Candida infections in AIDS
Fluconazole | Posaconazole
44
Uncomplicated vulvovaginal candidiasis (VVC)
Flucanazole
45
Antimycobacteral
You made it another lecture
46
Active TB in pregnant
INH Rifampin Ethambutol X 9 months No streptomycin
47
LTBI in kids 2-11 and comorbid adults (preggo/AIDS)
INH + pyridoxine(B6) X 9 months
48
LTBI over 12
INH and rifampin x 3 months
49
Mycobacterium avium complex (MAC)
Rifabutin
50
TB infection
Rifampin
51
Latent TB
INH + B6
52
Combination for: M. TB M. LEprae M. Kansasii
Rifampin
53
Prophylactically or tx of | Meningitis caused meningococci or H. influenzae
Rifampin
54
LTBI tx for preggo
INH 1 x daily x 9 months | Pyridoxine supplements
55
Multi drug therapy for M. TB
INH: isoniazid RIF: rifampin PZA: pyrazinamide EMB: ethambutol
56
Second line for TB
Rifabutin Rifapentine Streptomycin
57
Active TB in preggo
INH, RIF, EMP x 9 months
58
M. Leprae aka hansen’s disease
Less severe: -dapsone + rifampin x 6-12 mo More severe: Dapsone + rifampin + cofazimine x 12-24 mo
59
Viral lecture
You survived TB
60
Cytomegalovirus, tx and prevention
Ganciclovir (cytovene-IV) | Valganciclovir (prodrug)
61
2nd line for CMV
Foscarnet (foscavir) IV | Cidofovir (vistide) IV
62
Prevent CMV post transplant
Valganciclovir (valcyte) PO
63
Influenza in preggo
Oseltamivir
64
HBV
Pegasys - a= preferred for HBV - b= FDA approved for HBV
65
HBeAG pos
1st line: (4-12 mo) - INFa - PEG-INFa ``` 2nd line (>12 mo) - entecavir or tenofovir PO ```
66
HBeAG neg
1st line (at least 12 mo) - INFa - PEG-INFa ``` 2nd line (>12 mo) - entecavir or tenofovir PO ```
67
Oral agents for HBeAg pos and HBeAG neg?
Entecavir and tenofovir
68
Resistant HBV
Lamivudine or telbivudine resistance: - add adefovir or tenofovir or - change to entecavir Adefovir resistance: - add lamivudine Entecavir resistance: - change to tenofovir
69
Shingles (herpes zoster)
Vanacyclovir Famciclovir Acyclovir
70
Genital herpes simplex
Vanciclovir
71
HIV+ preggo Antepartum stage
Emtricitabine/tenofovir (truvada) | Raltegravir (isentress)
72
HIV + preggo Intrapartum
Antepartum + Zidovudine
73
HIV+ mom | Infant prophylaxis
Low risk: zidovudine 4-6 weeks High risk: combo regimen
74
Occupational (<72hrs) post exposure prohyplaxis (PEP)
Emtricitabine/tenofovir (truvada) | Raltegravir (isentress)
75
Herpes encephalitis
Acyclovir IV q 8 hrs’ Followed by Oral antiviral q 10 days
76
Difficult to treat HSV infection
Acyclovir IV
77
HIV pre-exposure prophylaxis (PrEP)
Emtricitabine (FTC) + Tenofovir disoproxil fumarate (TDF) (truvada)
78
Treatment experienced pts that blocks HIV fusion w CD4 pt to block entry into human cell?
Enfuviritide (fusion inhibitor)
79
Parasite
Thank god, another one down
80
Hydrocele from lymphatic filariasis (roundworm, elephantiasis)
Surgery
81
Lymphatic filariasis
Diethycarbamazine (DEC)
82
Sensitive p. falciparum
Chloroquine (aralen)
83
Chemoprophylaxis in areas w chloroquine resistant P. Falciparum
Doxycycine (vibramycine)
84
Mild to moderate C. Diff
Metronidazole
85
Trichomas vaginalis
Metronidazole or tindazole
86
Pneumpcystis jiroveci pneumonia (PCP)
Sulfamethozazole/trimethoprim (septra)

Junior - Pharm II - 3 (1 decks)

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