Dopamine Pathways Flashcards by Katie Clark

Mesolimbic

Connects VTA to nucleus accumbens
Overactive= high dopamine

⬇️dopamine to treat positive symptoms

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Mesocortical

Connects VTA to cortex
Underactive= low dopamine = negative symptoms

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Nigrostriatal

Connect substantia Nigra (responsible for coordinating movement) to dorsal striatum
⬇️dopamine leads to ⬆️ acetylcholine = Parkinson’s
⬆️dopamine leads to ⬇️acetylcholine= Alzheimer’s

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Tuberoinfundibular

Connects hypothalamus to pituitary gland(release prolactin)

⬆️ dopamine= ⬇️prolactin

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