Dosages

Question 1

Dopamine (therapeutic dosage range and responses)

Answer 1

• 2.0 to 5.0 mcg/kg/min: negligible beta-adrenergic responses
• 5.0 to 10 mcg/kg/min: beta-adrenergic responses (positive chronotropic and inotropic effects)
• 10 to 20 mcg/kg/min: alpha-adrenergic responses (vasoconstriction, increased blood pressure and increased preload)
• > 20 mcg/kg/min: may increase the heart rate and myocardial oxygen demand to undesirable limits.

Question 2

Acetaminophen (adult dose)

Answer 2

325 to 1,000 mg every 4 to 6 hours
Maximum 4.0 g daily

Question 3

Acetylsalicylic acid (ASA) adult dose

Answer 3

160 to 325mg

Question 4

Activated charcoal (adult dose)

Answer 4

30 to 60gm (1.0 to 2.0 gm/kg)

Question 5

Adenosine (adult dose)

Answer 5

6.0mg RAPID bolus over 1 to 3 seconds follow by 20 cc normal saline flush
If no response to the initial bolus after 1 to 2 minutes, administer 12 mg RAPID bolus over 1 to 3 seconds followed by 20 cc normal saline flush

Question 6

Albuterol sulfate (adult dose)

Answer 6

• 2.5mg in 3.0mL normal saline (unit dose) via SVN
• 2.5mg in 3.0mL normal saline (unit dose) via in-line SVN with a bag-valve mask
• May repeat the dosage

Question 7

Amiodarone (adult dose)

Answer 7

• Cardiac arrest: 300mg
• If no response, administer 150 mg over 3 to 5 minutes
• Tachydysrthymias: 150mg in 50mL D5W infused over 10 minutes
• Infusion: 1.0mg/min

Question 8

Atropine sulfate (adult dose)

Answer 8

• Hemodynamically significant bradycardia: 1.0mg
• May repeat the dosage every 3 to 5 minutes to maximum dosage 3.0mg
• Organophosphate poisoning/carbamate poisoning/nerve agent exposure: 1.0 to 4.0mg
• May double the dosage every 5 minutes
• ET: 2.0 to 2.5mg diluted in 10mL normal saline

Question 9

Bumetanide (adult dose)

Answer 9

0.5 to 1.0mg

Question 10

Calcium chloride (adult dose)

Answer 10

• 500 to 1,000mg (0.5 to 1.0gm)
• May repeat the dosage in 10 minutes

Question 11

Calcium gluconate 2.5% topical gel (adult dose)

Answer 11

If possible, patient should wash affected area & massage the gel into the skin

Question 12

Calcium gluconate (adult dose)

Answer 12

• Hyperkalemia: 1.0 gm
• May repeat the dosage

Question 13

Dexamethasone (adult dose)

Answer 13

8.0 to 24mg

Question 14

Dextrose 50% (adult dose)

Answer 14

12.5 to 25gm

Question 15

Diazepam (adult dose)

Answer 15

2.0mg increments over 2 minutes

Question 16

Diltiazem (adult dose)

Answer 16

• 0.25mg/kg (usually 20mg) over 2 minutes
• May repeat the dosage 0.35 mg/kg (usually 25mg) in 15 minutes
• Infusion: 5.0 to 15 mg/hour

Question 17

Diphenhydramine (adult dose)

Answer 17

• Allergic reaction/anaphylaxis: 25 to 50mg
• Phenothiazine reaction with extrapyramidal symptoms: 10 to 50mg

Question 18

Dopamine (adult dose)

Answer 18

Infusion: 2.0 to 20 mcg/kg/min (reference the Dopamine Dosage Chart)

Question 19

Epinephrine (adult dosages)

Answer 19

• Cardiac arrest: 1.0 mg (1:10,000) IV/IO
• May repeat the dosage every 3 to 5 minutes during resuscitation
• Cardiac arrest: 2.0 to 2.5 mg (1:1,000) ET diluted in 10mL normal saline
• May repeat the dosage every 3 to 5 minutes during resuscitation
• Hemodynamically significant bradycardia: 2.0 to 10.0 mcg/min infusion
• Hemodynamically significant hypotension: 2.0 to 10.0 mcg/min infusion
• Bronchospasm associated with chronic bronchitis and emphysema/allergic reaction/anaphylaxis : 0.3 to 0.5 mg (1:1,000) IM Adult EpiPen auto injector 0.3mg IM

Question 20

Etomidate (adult dose)

Answer 20

0.2 to 0.6 mg/kg (usually 20mg) over 30 to 60 seconds

Question 21

Fentanyl (adult dose)

Answer 21

• 25 to 50 mcg
• Max dosage 200 mcg

Question 22

Furosemide (adult dose)

Answer 22

• If the patient is prescribed furosemide: the initial dosage is 2 times the patient’s total daily prescribed dosage of the drug (usually 40 to 80 mg)
• If the patient is not prescribed furosemide: 0.5 to 1.0 mg/kg (usually 30 to 40 mg)

Question 23

Glucagon (adult dose)

Answer 23

• 1.0 mg
• May repeat the dosage in 7 to 10 minutes

Question 24

Hydroxocobalamin (adult dose)

Answer 24

• 5.0 gm over 15 minutes

Question 25

Ibuprofen (adult dose)

Answer 25

400 to 800 mg every 6 to 8 hours

Question 26

Ipratropium bromide (adult dose)

Answer 26

• 500 mcg (0.5 mg) in 2.5 mL normal saline (unit dose) via small volume nebulizer • In-line with a bag-valve mask: 500 mcg (0.5 mg) in 2.5 mL normal saline (unit dose) via SVN • May repeat the dosage

Question 27

Ketamine (adult dose)

Answer 27

• IV/IO: 1.0 to 2.0 mg/kg over 1 minute • IM: 2.0 to 4.0 mg/kg

Question 28

Lidocaine (adult dose)

Answer 28

• VF and pulseless VT: 1.0 to 1.5 mg/kg • May repeat the dosage 0.5 to 0.75 mg/kg every 3 to 5 minutes during resuscitation • Maximum dosage 3.0 mg/kg • Ventricular dysrhythmias with a pulse: 1.0 to 1.5 mg/kg • May repeat the dosage 0.5 to 0.75 mg/kg in 5 to 10 minutes • Maximum dosage 3.0 mg/kg • Maintenance infusion: 2.0 to 4.0 mg/minute • ET: 2.0 to 2.5 times the bolus dosage diluted in 10mL normal saline

Question 29

Lorazepam (adult dose)

Answer 29

• Seizure IV/IO: 2.0 to 5.0 mg over 2 minutes • Seizure IM: 2.0 to 5.0 mg • Procedural sedation IV/IO: 2.0 mg over 2 minutes • Procedural sedation IM: 4.0 mg • Maximum dosage: 10 mg

Question 30

Magnesium sulfate (adult dose)

Answer 30

• Torsades de pointes infusion: 1.0 to 2.0 gm in 50 to 100 mL over 5 minutes • May repeat the dosage 1.0 to 2.0 gm over 1 hour • Pre-term labor/pre-eclampsia/eclampsia infusion: 3.0 to 6.0 gm in 100 mL over 10 to 20 minutes • May repeat the initial dosage • Maintenance infusion: 1.0 to 4.0 gm/hour • Reactive airway conditions: 2.0 gm in 50 mL over 5 to 10 minutes • Cardiac arrest IV/IO: 1.0 to 2.0 gm over 1 to 2 minutes

Question 31

Methylprednisolone (adult dose)

Answer 31

125 mg

Question 32

Midazolam (adult dose)

Answer 32

• Seizure IV/IO: 0.1mg/kg • Maximum dosage: 4.0 mg • Seizure IM: 0.2 mg/kg • Maximum dosage: 10mg • Procedural sedation IV/IO: 0.5 to 2.5 mg • Maximum dosage: 0.1 mg/kg • Chemical restraint IV/IO: 0.05 to 0.1 mg/kg • Chemical restraint IM: 0.1 to 0.15 mg/kg

Question 33

Morphine sulfate (adult dose)

Answer 33

1.0 to 4.0 mg increments over 1 to 5 minutes

Question 34

Morphine sulfate (adult dose)

Answer 34

1.0 to 4.0 mg increments over 1 to 5 minutes

Question 35

Naloxone (adult dose)

Answer 35

• 2.0 mg • May repeat the dosage every 2 minutes • ET: 4.0 mg diluted in 10 mL normal saline • Intra-nasal (IN): 1.0 mg sprayed in each nostril • May repeat the dosage every 2 minutes