Dosages

Question 1

Epi Grade II treatment

Answer 1

10-20 mcg SC/IM

Question 2

Vasopressin anaphylaxis treatment

Answer 2

2 - 10 units for epinephrine unresponsiveness

Question 3

Epi grade III treatment

Answer 3

100-200 mcg SC/IM/IV q1-2 mins;
1-4 mcg/min (infusions)

Question 4

Epi grade IV Treatment

Answer 4

1 mg IV repeat as needed
4-10 mcg/min infusion

Question 5

IV fluid treatment for volume expansion in anaphylaxis

Answer 5

crystalloid 10-30 ml/kg
or
colloid 10 ml/kg

Question 6

Anaphylactic treatment:
pre-op beta blockade w/ Glucagon

Answer 6

1-5 mg IV q 5 min;
5-15 mcg/min

Question 7

Anaphylactic treatment:
H1 - benadryl treatment

Answer 7

0.5-1 mg/kg (max 50 mg)

Question 8

Anaphylactic treatment:
H2 – famotidine (Pepcid)

Answer 8

20 mg

Question 9

Anaphylactic treatment:
Terbutaline

Answer 9

0.25 mg SC
may repeat in 15-30 mins

Question 10

Anaphylactic treatment:
hydrocortisone

Answer 10

250 mg IV

Question 11

Anaphylactic treatment:
adjunct epi infusion

Answer 11

0.05 – 0.1 mcg/kg/min

Question 12

Anaphylactic treatment:
adjunct NorEpi infusion

Answer 12

0.05 – 0.1 mcg/kg/min

Question 13

Anaphylactic treatment:
adjunct NaBicarb

Answer 13

0.5 – 1 mEq/kg initially, then titrate to ABGs

Question 14

daily corticosteroid release (normal)

Answer 14

20 mg daily with more secreted during the day and less at night

Question 15

The Stress response – output increases secretion to how much?

Answer 15

200 mg daily
50 mg/day – minor surgery
75-150 mg/day – major surgery

Question 16

Elimination ½ life of corticosteroid release

Answer 16

70 minutes
NO STORAGE

Question 17

minor surgery steroid coverage dosing
(hernia repair, colonoscopy)

Answer 17

Preoperative corticosteroid dose + hydrocortisone 25 mg or equivalent

Question 18

moderate surgery steroid coverage dosing
(colon resection, hysterectomy, joint replacement)

Answer 18

Preoperative corticosteroid dose + hydrocortisone 50-75 mg or equivalent; taper by 50% per day over 1-2 days

Question 19

major surgery steroid coverage dosing
(cardiac, thoracic, liver surgeries)

Answer 19

Preoperative corticosteroid dose + hydrocortisone 100-150 mg, taper by 50% per day over 1-2 days

Question 20

antiemetic of dexamethasone dose

Answer 20

0.15 mg/kg
best if given before induction

Question 21

Prochlorperazine (Compazine) dosing:

Answer 21

2.5 - 10 mg IV

Question 22

promethazine (Phenergan)

Answer 22

25 mg IV

Question 23

scopolamine antiemetic dosing

Answer 23

apply patch 60 mins prior to induction
5 mcg/hr for 72 hours
total dose absorbed less than 0.5 mg

Question 24

Butyrophenones (droperidol, Inapsine)

Answer 24

0.625 - 1.25 mg IV
(watch for prolonged QT interval)

Question 25

Metoclopramide (Reglan)

Answer 25

10 - 20 mg IV

Question 26

Ondansetron (Zofran)

Answer 26

4-8 mg (0.15mg/kg) IV

Question 27

Dolasetron (Anzemet)

Answer 27

12.5 mg IV

Question 28

Granisetron (Kytril)

Answer 28

1 mg (0.01 mg/kg) IV

Question 29

Palonosetron (Aloxi)

Answer 29

0.075 mg IV

Question 30

Aprepitant (Emend)

Answer 30

40 mg PO one hour pre-op

Question 31

Amisulpride (Barhemsys)

Answer 31

10 mg single IV dose administered over 1 to 2 minutes

Question 32

propofol antiemetic dose

Answer 32

0.5 mg/kg or 10-15 mg (sub-induction dose)

Question 33

Ephedrine antiemetic dose

Answer 33

0.5 mg/kg IM IM ephedrine equal to droperidol IV

Question 34

premedication fentanyl dose to blunt laryngoscopy response

Answer 34

5 - 8 mcg/kg

Question 35

premedication: Normal fentanyl dose

Answer 35

1 -2 mcg/kg IV

Question 36

diphenhydramine pre-med dose

Answer 36

0.5 - 1mg/kg PO

Question 37

clonidine pre-med dose

Answer 37

5 mcg/kg PO 90 mins

Question 38

dexmedetomidine pre-med dose

Answer 38

-PEDS 1-2 mcg/kg intranasally 0.5 mcg/kg IV (decrease analgesia requirment)

Question 39

aspiration prophylaxis goal

Answer 39

gastric pH > 2.5 gastric volume < 25 ml (0.4 ml/kg)

Question 40

cimetidine (Tagamet) pre-med dose

Answer 40

150-300 mg PO or IV (60-90 mins) lasts 4-6 hrs

Question 41

ranitidine (Zantac)

Answer 41

150-300 mg PO 50 mg IV (60-90 mins) lasts up to 9 hours

Question 42

famotidine (Pepcid) pre-med dose

Answer 42

20-40 mg PO 20 mg IV (60-90 mins) - lasts 10-12 hrs

Question 43

metoclopramide (Reglan) pre-med dose

Answer 43

10-15 mg PO (30-60 mins) 10 mg IV (15-30 mins) PEDS 0.25 mg/kg

Question 44

sodium citrate (Bicitra) pre-med dose

Answer 44

15-30 ml (15-30 mins)

Question 45

omeprazole (Prilosec) pre-med dose *she said dont need to know, but I have trust issues

Answer 45

20 mg single dose > 3 hours to increase pH

Question 46

steroid equivalent doses: cortisol and methylprednisolone

Answer 46

cortisol: 20 mg methylprednisolone: 4 mg

Question 47

steroid equivalent doses: dexamethasone and prednisone

Answer 47

dexamethasone: 0.75 mg prednisone: 5 mg

Question 48

steroid equivalent doses: dexamethasone and cortisol

Answer 48

dexamethasone: 0.75 mg cortisol: 20 mg

Question 49

steroid equivalent doses: prednisone and methylprednisolone

Answer 49

prednisone: 5 mg methylprednisolone: 4 mg