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Dosages NMBs, LAs, Pressors Flashcards

(53 cards)

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1
Q

What is the dose of Succinylcholine?
Onset:
Duration:
Metabolism:

A

Succinylcholine (Anectine)
Dose: 1 mg/kg IV
Onset: 30-60 seconds
Duration: 3-5 minutes
Metabolism: pseudocholinesterase

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2
Q

Dantrolene
Dose:
Metabolism:

A

Dantrolene (Ryanodex)
Dose: 2mg/kg IV
Repeat doses until symptoms subside or 10mg/kg IV
Metabolism: Hepatic

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3
Q

What is the dose of SCh for MG patients?

A

1.5-2.0 mg/kg
(increased d/t resistance)

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4
Q

For a patient with burns needing intubation, how can we offset the resistance to non-depolarizing blockers the burn causes?

A

1.2 mg/kg dose of Rocuronium

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5
Q

Pancuronium
Dose:
Onset:
Duration:
Metabolism:

A

Pancuronium (Pavulon)
- Dose: 0.1mg/kg;
- Onset: 3-5 minutes;
- Duration: 60-90 minutes
Metabolism: Hepatic
Excretion: 80% unchanged in Urine

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6
Q

Vecuronium
Dose:
Onset:
Duration:
Metabolism:

A

Vecuronium (Norcuron)
- Intubating Dose: 0.1 mg/kg
- Onset: 3-5 minutes
- Duration: 20-35 minutes
Metabolism: 70% Hepatic
Excretion: 30% unchanged in Urine

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7
Q

Rocuronium
Normal Dose:
Onset:
Duration:
Metabolism:
Excretion:

A

Rocuronium (Zemuron)
* Dose: 0.6 mg/kg
* Onset: 3-5 minutes
* Duration: 20-35 minutes
Metabolism: Hepatic
Excretion: Bile, 10-30% Renal

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8
Q

Rocuronium
RSI Dose:
Onset:
Duration:
Metabolism:
Excretion:

A

Rocuronium (Zemuron)
- Dose: 1.2 mg/kg
- Onset: 1-2 minutes
- Duration: 60-90 minutes
Metabolism: Hepatic
Excretion: Bile, 10-30% Renal

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9
Q

Cisatracurium
Dose:
Onset:
Duration:
Metabolism:

A

Cisatracurium (Nimbex)
* Intubating Dose: 0.1 mg/kg;
* Onset: 3-5 minutes;
* Duration of action: 20-35 minutes
Metabolism: Hoffman elim & plasma cholinesterase

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10
Q

Mivacurium
Dose:
Onset:
Duration:
Metabolism:

A

Mivacurium (Mivacron)
* Intubating Dose: 0.15 mg/kg;
* Onset: 2-3 minutes (Conditions less desirable);
* Duration: 12-20 minutes
Metabolism: plasma cholinesterase

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11
Q

Neostigmine
Dose:
Max:
Onset:
Duration:

A

Neostigmine (prostigmine)
Dose: 40 - 70 mcg/kg
Max: 5mg
Onset: 5-10 min
Duration: 60 min

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12
Q

Edrophonium
Dose:
Onset:
Duration:

A

Edrophonium (Tensilon)
Dose: 0.5 - 1 mg/kg
Onset: 1-2 min
Duration: 5-15min

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13
Q

What is the dose of Atropine?

A

7 - 10 mcg/kg

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14
Q

What is the Sugammadex dose for a moderate block?
Onset:
Duration:
Elimination:

A

Sugammadex (Bridion)
2 mg/kg
Onset: 1-4 min
Duration: 1.5 - 3 hours
Elimination: Urine

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15
Q

What is the Sugammadex dose for a deep block?

A

4 mg/kg

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16
Q

What is the sugammadex dose for an extreme block?

A

8 - 16 mg/kg

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17
Q

What drug and dose would be a good choice for a recurarizing patient in the PACU?
Why might this be a good choice?

A
  • Neostigmine 0.05 mg/kg IV (40-70mcg/kg)
  • Longer duration of action (60min)
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18
Q

What is the dose and max for glycopyrrolate?

A

7 - 15 mcg/kg

1mg maximum

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19
Q

MAGA: What is the intra-op infusion dose of lidocaine?

A

1 mg/kg over an hour

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20
Q

What is the IV dose of Lidocaine? (bolus and drip)

A
  • 1 to 2 mg/kg IV (initial bolus) over 2 - 4 min.
  • 1 to 2 mg/kg/hour (drip)
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21
Q

What is Lidocaine’s max infiltration dose? (with and without Epi)

A
  • 300 mg plain
  • 500 mg with Epi
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22
Q

What is the max dose of prilocaine?

23
Q

What is the treatment and dose for methemoglobinemia secondary to prilocaine overdose?

Study These Flashcards
A

Methylene Blue

  • 1 to 2 mg/kg IV over 5 mins (initial dose)
  • Total dose not to exceed 8 mg/kg
24
Q

Benzocaine
Onset:
Duration:
Dose:

Study These Flashcards
A

onset: rapid

duration: 30-60 min

Dose: 200-300 mg = 20% spray

25
**Lidocaine max single dose** Infiltration: Topical: Epidural: Spinal: PNB:
* Infiltration: 300mg or 500mg with Epi * Topical: 300 mg * Epidural: 300mg or 500mg with Epi * Spinal: 100mg * PNB: 300mg or 500mg with Epi
26
Prilocaine Recommended Max Single Dose for infiltration/IVRA/PNB/Epidural?
600 mg
27
Bupivacaine Recommended Max Single Dose Bupivacaine Recommended Max Single Dose with/Epi Bupivacaine Recommended Max Single Dose for Spinal
175 mg 225 mg w/ Epi Spinal max: 20 mg
28
Eutectic Mixture of LA (EMLA) contains what two local anesthetics? Dose: Onset:
Lidocaine 2.5% + Prilocaine 2.5% = 5% LA Dose: 1 to 2 g/ 10 cm² area Onset: 45 mins
29
What is the dose of bupivacaine for the scenario below? 5 ft tall patient = _____mL of ____% Bupivacaine + ______ mL for every inch above…. 2 cc total ( 1½ hours to 2 hours)
1 mL of 0.75% Bupivacaine 0.1 mL *For someone who is 5'5", you will give 1.5 mL of 0.75% bupivacaine for a SAB.*
30
What makes up the tumescent solution?
* Diluted Lidocaine (0.05% to 0.1%) * Epinephrine 1:100,000
31
What is the dose for Regional Anesthesia Lidocaine with Epi?
7 mg/kg
32
Highly diluted Lidocaine with Epi Tumescent dose.
35 to 55 mg/kg
33
What is the bolus dose of Lipid Emulsion?
1.5 mL/kg of 20% lipid emulsion
34
What is the **infusion dose** of lipid emulsion? How long should it be given?
0.25 mL/kg/minute for at least 10 minutes
35
What is the max total dose for lipid emulsion that should be given?
8 mL/kg
36
If cardiac arrest occurs with LAST syndrome, how should our epinephrine dosing change?
Small doses (**10mcg - 100mcg boluses**) are preferred with LAST ACLS.
37
What is the treatment for methemoglobinemia? What is the max dosage?
Methylene blue 1mg/kg over 5min max: 8 mg/kg
38
What is the dose for Atenolol?
5mg q10min IV
39
What is the dose of metoprolol?
1mg q5min (Given in 5mg "blocks")
40
What is the initial dose for esmolol?
20-30mg IV
41
What is the normal dosing of phenylephrine?
50-100mcg IV push
42
What is the dose for labetalol? How long would it take to see max effect from IV dose?
2.5 - 5mg IV; 10mg max IV max effect 5-10 min
43
What is the IV push dose of epinephrine? How long does it last?
- 2-8mcg IVpush - 1-5 min
44
What is the infusion dose of epinephrine for β2 effects?
1-2 mcg/min
45
What is the infusion dose of epinephrine for β1 effects?
4 mcg/min
46
What is the infusion dose of epinephrine for predominantly α effects?
10-20 mcg/min
47
Which SNS agonist can be given IM? What dose? Why would this be done?
- Ephedrine IM 50mg - Long lasting increase in BP for OB patients.
48
What is the dose of Nitroprusside?
Initial: 0.3 mcg/kg/min Tritrate slowly to 2 mcg/kg/min
49
What is the nitroglycerin dose?
Initial: 5 - 10 mcg/min
50
What is the initial dose of hydralazine?
2.5mg IV
51
What is the dose of nicardipine?
5mg/hr (↑2.5mg x4hr) max 15mg/hr
52
What is the single IV push dose for ephedrine?
5-10mg IV
53
What is the single IV dose for vasopressin?
1-2 units IV

.Drug Doses/Info (23 decks)

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