dosing Flashcards
(18 cards)
pharyngitis adult first line
penicillin 600 mg bid (or 300mg tid) x 10 days
pharyngitis alternatives
cephalexin 500 mg po bid 10 days
clindamycin 300 mg tid 10 days
azithromycin 500 mg po daily 3 days
clarithromycin 250 mg po bid 10 days
pharyngitis children 1st line
penicillin 40mg/kg/day po divided dose bid 10 days
amoxicillin 50mg/kg/day po divided bid 10 days
pharyngitis children alternatives
cephalexin 40 mg/kg/day po bid 10 days
clindamycin 20 mg/kg/da tid 10 days
azithromycin 20mg/kg/day po daily 3 days (avoid) `
clarithromycin 15mg/kg/day po divided bid 10 days
pharyngitis failure
worsening of syms after 72 hour atx
early relapse (2-7 days) post therapy
late relapse or recurrent confirm by culture
adult:
amoxicillin/clavulanante 875 mg po bid 10 days
clindamycin 300 mg po tid 10 days
azithromycin or clarithromycin
children:
clindamycin, azithromycin, clarithromycin
what to avoid pharyngitis
fluoroquinolones
tmp/smx
macrolides and clindamycin
adjunctive trx with cc not indicated: doesnt improve pain, may delay recovery
sinusitis adult first line
amoxicillin 500-1000mg po tid 5-7 days
sinusitis alternative
severe/ immuno
beta-lactam allergy
amoxi/clav 875mg po bid 5-7 days
doxycycline 200mg po 1 dose, then `00 mg po bid 5-7 days
levofloxacin 750 mg daily 5 days
sinusitis children
amoxicillin 40mg/kg/day po divided tid 10 days
amoxicillin 90mg/kg/day po divided bid-tid 10 days
- under 2, under 3months since last or attends daycare
sinusitis children alternatives
amoxi-clav 45mg/kg/day po divided bid-tid 10 days (+/- amoxi 45mg/kg/day po divided bid-tid 10 days)
doxycycline 4mg/kg/day po divided bid 10 dyas
levofloxacin 10-20 mg/kg/day po divided once or twice 10 days
clindaycin 20-30 mg/kg/day po divide tid and cefixime 8mg/kg/day divided bid 10 days
AOM ATX therapy should be initiated for
6 months or older with severe sym (toxic-appearing, persistent ear pain for longer than 48 hours or temp over 39
6 months or older with AOM with otorrhea
6-23 months with bilateral AOM
AOM first line over 6 months
amoxicillin 40mg/kg/day div tid (standard dose)
amoxicillin 90mg/kg/day div bid-tid (over 2yrs, recent atx exposure, daycare)
AOM concurrent purulent conjunctivitis
amoxi/clav 45mg/kg/day po div bid 5 days
nonsevere penicillin allergy AOM
cefuroxime axetil 30mg/kg/day div bid 5 days
severe penicillin allergy aom
doxycycline 4mg/kg/day div bid (>8yrs) 5 dyas or
tmp/smx 8-12 mg tmp /kg/day div BID 5 days
severe penicilling and local s. pneumonia tetracycline or tmp/smx resistence >20%
levofloxacin 10-20mg/kg/day div q12-24h
high risk aom
amoxi/clav 45mg/kg/day po div bid-tid and
amoxicillin 45mg/kg/day div bid-tid
10 days
failure of first line aom
failure of high dose amoxicillin
amoxi/clav 45mg/kg/day po div bid-tid and
amoxicillin 45mg/kg/day div bid-tid
10 days
amoxi/clav 45mg/kg/day po div bid-tid 10 days
