Down's Syndtome Flashcards
1
Q
90% of DS cases
A
Trisomy 21 Occurs during meiosis Nondisjunction during cell division Extra copy of chromosome 21 Less chance of survival
2
Q
6% of DS cases
A
Mosaic DS
Occurs after conception
Some calls have extra copy of Chrm 21
Later mistake is made= less copies
3
Q
4% of cases
A
Translocation
Occurs during meiosis
2 copies of chrm 21 and extra material trans located to chrm 14
50% inherited
Robertsonian translocation (centric fusion)
Breaks extreme ends of haploidchroksomes
Creates a longer chromosome
4
Q
Developmental changes up to 6 months
A
More dendritic branching and greater length
5
Q
Arbors are substantially
A
Decreasing throughout life
6
Q
Info processing and plasticity is caused by
A
Reduced and abnormally connected networks
